Kouhei Onishi

ORCID: 0000-0003-2870-5750
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About
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Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Vascular Malformations Diagnosis and Treatment
  • CNS Lymphoma Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Epilepsy research and treatment
  • Cerebral Venous Sinus Thrombosis
  • Moyamoya disease diagnosis and treatment
  • Bone Tumor Diagnosis and Treatments
  • Acute Ischemic Stroke Management
  • Neurological Complications and Syndromes
  • Pituitary Gland Disorders and Treatments
  • Immune Cell Function and Interaction
  • Spinal Dysraphism and Malformations
  • Older Adults Driving Studies
  • Lymphoma Diagnosis and Treatment
  • Bone and Joint Diseases
  • Glioma Diagnosis and Treatment
  • Nitric Oxide and Endothelin Effects
  • Neuroscience and Neuropharmacology Research
  • Meningioma and schwannoma management
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Spinal Fractures and Fixation Techniques
  • Pharmacological Effects and Toxicity Studies
  • Neurofibromatosis and Schwannoma Cases
  • Spinal Hematomas and Complications

Oita University
2013-2024

Abstract Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) is a new immune checkpoint molecule and its role of primary central nervous system lymphoma (PCNSL) tumor microenvironment has been unclear. We explored the Siglec-15 programed death-ligand 1 (PD-L1) expression in tissues analyzed association between these molecules overall survival newly diagnosed PCNSL. A total 60 patients with diffuse large B-cell PCNSL were included this study. The PD-L1 on cells, intratumoral...

10.1038/s41598-020-79742-9 article EN cc-by Scientific Reports 2021-01-13

Introduction: Although many surgical treatment strategies for Chiari malformation type I (CM-I) have been reported, the most appropriate technique remains controversial. It is wholly ascribable to complicacy of pathological condition in CM-I. Recently, intraoperative neurophysiologic monitoring (INM) becoming prevalent spinal surgery. Indeed, motor-evoked potentials (MEPs) and somatosensory-evoked (SSEPs) are standard tools minimize risk neurologic injury postoperative deficits. The recent...

10.1097/scs.0000000000003926 article EN Journal of Craniofacial Surgery 2017-09-01

Objectives The anticonvulsant and antioxidant effects of lamotrigine on status epilepticus (SE) are incompletely understood. We assessed these pilocarpine (Pilo)-induced SE in mice. Methods Male C57BL/J6 mice were assigned to three groups: the control group, Pilo (400 mg/kg, s.c.)-induced (Pilo group) (20 i.p.) treated (Pilo/lamotrigine group). latency Racine’s stage 3 or higher, mortality rate within 2 h administration, duration until sacrifice examined. Nitric oxide (NO), malondialdehyde...

10.1097/wnr.0000000000001859 article EN Neuroreport 2022-11-30

A 74-year-old male presented with an intracranial hemorrhage caused by multiple dural arteriovenous fistulas (DAVFs) in the left transverse sinus and right sigmoid sinus. Four months previously, patient underwent tongue cancer removal lymph node dissection ligation of internal jugular vein. Endovascular embolization (transvenous transarterial embolization) resulted complete disappearance fistulas. Follow-up angiography revealed new shunts at superior sagittal sinus, we treated staged...

10.2176/nmccrj.cr.2016-0258 article EN NMC Case Report Journal 2017-01-01

Although osseous involvement is occasionally observed in spinal epidural arteriovenous fistulas (AVFs) or seen as a part of diseases metameric syndrome, purely intraosseous AVFs are extremely rare. Their clinical and imaging characteristic features not well known. The authors present case associated with compression fracture.A 76-year-old man presented back pain progressive myelopathy. Computed tomography showed fracture the T12 vertebral body dilatation perimedullary veins. Spinal...

10.3171/case22184 article EN Journal of Neurosurgery Case Lessons 2022-07-25

Abstract PURPOSE R-MPV-A therapy has recently been reported to improve the outcomes of primary central nervous system lymphoma (PCNSL). Our patients have received since 2017 and elderly only treated with whole brain radiotherapy when they do not show a complete response after induction chemotherapy. We report therapeutic problems PCNSL R-PMV-A. MATERIALS & METHODS Eight newly diagnosed R-MPV from September June 2019. retrospectively reviewed cycles therapy, radiotherapy, consolidation...

10.1093/noajnl/vdz039.149 article EN cc-by-nc Neuro-Oncology Advances 2019-12-01

Posterior reversible encephalopathy syndrome (PRES) is identified on magnetic resonance imaging by posterior predominant white and gray matter lesions. PRES secondary to spinal disease very rare. We report a case of clinical findings about associated with epidural hematoma.

10.22541/au.161401046.66610178/v1 preprint EN Authorea (Authorea) 2021-02-22
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