- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neural Engineering
- Epigenetics and DNA Methylation
- Neuroscience of respiration and sleep
- Functional Brain Connectivity Studies
- Neuroendocrine regulation and behavior
- Genetics and Neurodevelopmental Disorders
- Neurogenesis and neuroplasticity mechanisms
- Liver Disease Diagnosis and Treatment
- Ultrasonics and Acoustic Wave Propagation
- Sperm and Testicular Function
- Protein Kinase Regulation and GTPase Signaling
- Spinal Cord Injury Research
- Mechanics and Biomechanics Studies
- Ion channel regulation and function
- Retinal Development and Disorders
- Cytokine Signaling Pathways and Interactions
- Diabetes and associated disorders
- Pituitary Gland Disorders and Treatments
- Circadian rhythm and melatonin
- Climate Change and Health Impacts
- Prosthetics and Rehabilitation Robotics
- Systemic Lupus Erythematosus Research
Kyushu University
1989-2021
Nara Institute of Science and Technology
2013
Tokushima University
2011
Kurume Institute of Technology
1994-2009
Kyoto University
1993
Osaka University
1989
Osaka University Hospital
1988
In this study, we demonstrated that IL-6 was a possible autocrine growth factor for rat mesangial cells (MC). rIL-6 induced in vitro of MC at concentration 2 to 200 ng/ml and activity found the supernatant cultured MC. Northern blot analysis as well situ hybridization revealed mRNA expressed Of urine samples from patients with proliferative glomerulonephritis (PGN) 50% were contain significant (ranging 30 126 pg/ml). Urine other type primary glomerular diseases such minimal change nephrotic...
Functional mapping of the human motor cortex related to hand and foot area was carried out using focal magnetic stimulation brain. The basic idea localized brain is concentrate induced eddy currents locally in vicinity a target by pair opposing pulsed fields. A figure-eight coil positioned outside head so that time-varying fields could pass through opposite directions around target. It observed an optimum direction stimulating for neural excitation exists each functional cortex. maps were...
1. The effects of local applications prostaglandin E2 (PGE2) on the unit activity fifty‐one neurones in organum vasculosum lamina terminalis (OVLT) region and fifty‐eight preoptic area (POA) were investigated small tissue slices from rat hypothalamus containing OVLT POA isolated each other. 2. Of these, thirty twenty‐eight warm sensitive increased their discharge rate response to a rise temperature. One neurone one cold showed opposite type responses changes thermosensitivity these was still...
A method of localized stimulation the human brain and spinal cord is proposed. The basic idea to concentrate induced eddy currents locally in vicinity a target by pair opposing pulsed magnetic fields. coils are positioned outside head opposite directions around target. at expected flow together, which results an increased current figure-eight coil designed, carried out using ourselves as volunteers. show that selective realized with 5-mm resolution. functional mapping motor cortex related...
A method of focal and vectorial magnetic stimulation has been developed. The basic idea is to concentrate induced eddy currents in a target by pair opposing pulsed fields which can be produced figure-of-eight coil. Since the concentrated at beneath intersection coil flow direction parallel tangent two circular coils, achieved. neutral fibers excited easily when are stimulated neural fibers. Based on this principle, functional maps human motor cortex related hand foot areas have obtained. It...
Nuclear protein 95 KDa (Np95, also known as UHRF1 or ICBP90) plays an important role in maintaining DNA methylation of newly synthesized strands by recruiting methyltransferase 1 (DNMT1) during cell division. In addition, Np95 participates chromatin remodeling interacting with histone modification enzymes such deacetylases. However, its expression pattern and function the brain have not been analyzed extensively. We here investigated mouse brain, from developmental to adult stages. fetal is...
Although many reports concerning the effects of shock waves on human body have been published, their male reproductive system are not well known. This report examines spermatozoa and rat testes. Semen samples were placed in water at 37 °C 100, 200, 500, 1,000 applied. In proportion to an increasing number waves, sperm motility percentage viable decreased, while short-tailed increased. a second study 500 or applied testes infant adult Wistar rats. Hematomas observed macroscopically...
We have developed a method of focal and vectorial magnetic stimulation the brain to utilize us stimulate localized area cortex within 5 mm resolution. observed that an optimal direction stimulating currents for neural excitation exists in each functional cortex. also maps vary with Orientation current. To explain mechanism which is responsible producing this anisompic response stimulation, we model elicited by stimulation. The explains our observation induced current vectors reflect both...
The technique of magnetic stimulation has been applied to studies on the human brain and neurological research. This paper discusses changes peripheral blood flow after exposure stimulation. A 300% increase in mass rate occurred single pulsed (SMS) both directions: from periphery center, center periphery. Similarly, repetitive same directions increased by about 300 % over rest, but waveform responses was different that SMS. Hence, very significant increases were obtained using
Long latency responses (LLR) to magnetic stimulation of the spinal roots in human neck were obtained using single pulsed nerve stimulation. The effects repetitive median nerves on LLR also investigated. When was added nerve, motor evoked potentials (MEPs) changed 50-100 ms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The functional mapping of the human cortex related to hand and foot area was obtained by focal magnetic stimulation brain. figure-eight coil designed, carried out using authors as volunteers. localization target confirmed MRI. brain were sensitive change in direction stimulating currents. current for neural excitation reflects both anatomical organization fibers A
Long latency (95-110 ms) motor evoked responses (LRR) to magnetic stimulation of the human cortex were obtained by using single pulsed stimulation. The time duration between a nerve signal's initiation and activity varies with "functional path" chosen signals.