A5109104541- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Phytochemistry and biological activities of Ficus species
- Bladder and Urothelial Cancer Treatments
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Artificial Intelligence in Healthcare and Education
- Advanced MRI Techniques and Applications
- Heart Failure Treatment and Management
- Porphyrin and Phthalocyanine Chemistry
- Artificial Intelligence in Healthcare
- Colorectal Cancer Surgical Treatments
- Invertebrate Immune Response Mechanisms
- Lipoproteins and Cardiovascular Health
- Sperm and Testicular Function
- Hemodynamic Monitoring and Therapy
- T-cell and Retrovirus Studies
- Infective Endocarditis Diagnosis and Management
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Machine Learning in Healthcare
- School Health and Nursing Education
Universidade Nova de Lisboa
2025
Osaka Police Hospital
2013-2022
Nara Institute of Science and Technology
2000
Kanazawa University
1991-1996
Background Heart failure (HF) is a significant global health problem, affecting approximately 64.34 million people worldwide. The worsening of HF, also known as HF decompensation, major factor behind hospitalizations, contributing to substantial care costs related this condition. Objective This study aimed explore the perspectives professionals and data scientists regarding relevance, challenges, potential benefits using machine learning (ML) models predict decompensation from patients with...
To determine whether cardiac iodine-123 metaiodobenzylguanidine ((123)I MIBG) imaging is useful in predicting the prognosis of patients with chronic heart failure.Cardiac (123)I MIBG was done on entry to study. The washout rate calculated from anterior chest view images obtained 20 and 200 minutes after injection isotope. Study were divided into two groups rates above below 27% (the mean value + 2 SD normal subjects), then followed up.Tertiary referral centre.79 failure whom left ventricular...
To investigate the mechanisms of eosinophil activation in airways patients with asthma, we attempted to detect eosinophil-activating cytokines sputum extracts obtained from asthmatic during acute attacks or remission by survival assay. Purified guinea pig eosinophils were cultured presence absence extracts, and viability was measured on Day 4. Eosinophil derived moderate severe significantly higher than that for mild those other respiratory diseases, including bronchiectasis diffuse...
Hochu-ekki-to is a Chinese herbal medicine that has been used for unexplained male infertility with some favorable clinical results. However, the detailed mechanisms of effect this on have not disclosed. This study investigated effects sperm motility human semen. Sixteen semen samples were obtained from 14 normal volunteers. Semen incubated 1, 10, and 100 ug/mL solution in 5% CO2 37°C 1–6 h, was compared control groups (the untreated phosphate-buffered saline). The 10 μg/ mL h significantly...
Research Articles| March 27 2000 Assignment of the neuropsin gene (Prss19) to mouse chromosome band 7B4 by in situ hybridization Subject Area: Genetics S. Yoshida; Yoshida Division Structural Cell Biology, Nara Institute Science and Technology, Ikoma (Japan) Search for other works this author on: This Site PubMed Google Scholar A. Hirata; Hirata N. Inoue; Inoue Shiosaka Cytogenetics (2000) 88 (1-2): 97–98. https://doi.org/10.1159/000015497 Article history Published Online: Content Tools...
Abstract Background Subclinical inflammation is an important pathogenesis of developing and sustaining atrial fibrillation (AF). Because AF itself contribute to the inflammatory response, role baseline subclinical on recurrence after catheter ablation (CA) remains controversial in patients with persistent AF. Purpose To evaluate whether plasma C-reactive protein (CRP) levels, a sensitive marker inflammation, are associated following CA. Methods The analysis was performed from EARNEST-PVI...
Whole bladder wall photodynamic therapy using hematoporphyrin derivative and argon-dye laser light 630 nm was performed on 40 patients with mainly carcinoma in situ of the bladder. Two types scattering diffuser developed at our department were used: motor-driven endoscope-modified diffusers. The total energy density used 10 to 30 Joules/cm2. Of patients, 27 (67.5%) achieved complete response 5 (12.5%) partial 3-months follow-up. In 11 there no recurrence an average tumor-free time...
Sulfated schizophyllans and sulfated oligosaccharides were prepared their inhibitory effects on coagulation fibrinolysis examined. Some schizophyllans, which had a sulfur content of more than 10%, prolonged prothrombin time (PT) thrombin (TT). Interestingly, some related able to inhibit plasmin toward amidolysis.
Background: Infection associated with Cardiovascular Implantable Electronic Devices (CIED) is a serious complication high morbidity and mortality. Martin et al revealed in 2010 that all bacteria do not cause clinical infection some can colonize CIED without sign of infection. Since there were limited data on the etiology characteristics bacterial colonization, we investigated frequency, species, risk factors colonization its prognostic impact for Method: We started to enroll prospectively...
<sec> <title>BACKGROUND</title> Heart failure (HF) is a significant global health problem, affecting approximately 64.34 million people worldwide. The worsening of HF, also known as HF decompensation, major factor behind hospitalizations, contributing to substantial care costs related this condition. </sec> <title>OBJECTIVE</title> This study aimed explore the perspectives professionals and data scientists regarding relevance, challenges, potential benefits using machine learning (ML) models...
Acute heart failure: time to relax?/ Transcatheter mitral interventions 21 tus, reflecting iron stores and intracellular status, respectively.All patients were prospectively divided into 4 age groups: <50 (n=148), 50-59 (n=301), 60-69 (n=174), ≥70 years (n=113), respectively.Results: There was a trend towards the higher prevalence of ID in elderly with HFrEF (36%, 30%, 40% 41% -in aforementioned respective groups, p=0.07).There no differences TSAT, sTfR, MCV, MCH, MCHC, hsCRP NT-proBNP...
1264 Platelets / Oral anticoagulants: news from large trials and registries ies were performed on citrated PRP with thrombin as an agonist.I/R (30 min/48 h) brain injury was induced by transient middle cerebral artery occlusion.Stroke size assessed triphenyltetrazolium chloride (TTC) staining while neurological function determined RotaRod Bederson tests.Results: Platelet mass (number size) significantly increased in the oldC (Fig. 1A).Reticulated platelet counts higher yoC, suggesting...
In order to detect immunoreactive schizophyllan (SPG), one of the beta-1,3-glucans in solution, a murine anti-schizophyllan monoclonal antibody, SPG1-HS, was used as primary antibody for solid-phase enzyme-linked immunosorbent assay (ELISA). Polysaccharide-bovine serum albumin (BSA), and polysaccharide-bovine hemoglobin (Hb) conjugate were prepared an antigen. The absorbance at 490 nm ELISA directly proportional SPG concentration SPG-BSA or SPG-Hb conjugates, allowing accurate measurement...
Abstract Background Several previous studies reported anti-inflammatory effect of direct oral anticoagulant (DOAC). However, it was limited to basic pathological data with small sample size. Real-world large clinical is still scarce. Methods We conducted a single-center prospective observational registry NVAF patients treated DOACs: the DIRECT (UMINehz745.034333283). All nonvalvular atrial fibrillation (NVAF) (N=2216) who were users dabigatran (N=648), rivaroxaban (N=538), apixaban (N=599),...
Abstract Background Renal dysfunction is one of the high bleeding risk factors in patients with atrial fibrillation as presented HAS-BLED score. The impact renal function on is, however, still to be investigated era direct oral anticoagulants (DOAC). Methods We conducted a single-center prospective observational registry NVAF DOACs: DIRECT (UMINehz745.112933283). All (N=2216) who were users dabigatran (N=648), rivaroxaban (N=538), apixaban (N=599), or edoxaban (N=431) from 2011 2017 enrolled...
Abstract Funding Acknowledgements Type of funding sources: Private company. Main source(s): Johnson & KK OnBehalf OCVC Arrhythmia Investigators Background Predicting heart rate (HR) after restoration sinus rhythm (SR) remains one the challenges when performing catheter ablation (CA) persistent atrial fibrillation (AF). Purpose To evaluate association between pre-ablation HR during AF and post-ablation SR, whether reduction is associated with recurrence. Methods The analysis was performed...
Abstract Background Atrial fibrillation (AF) reduces the renal function. Renal dysfunction and AF often coexist. Catheter ablation (CA) of persistent can maintain a sinus rhythm may improve Purpose We sought to elucidate whether estimated glomerular filtration rate (eGFR) in patients with was increased after CA, especially presence an recurrence. Methods enrolled 487 whose eGFR data were available both before 1-year CA out 512 EARNEST-PVI trial. Results The mean age 65±9 year 113 (24.8%) had...