Toshiyasu Amano

ORCID: 0000-0002-9640-8718
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Research Areas
  • Hormonal and reproductive studies
  • Sexual function and dysfunction studies
  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Urinary Bladder and Prostate Research
  • Urological Disorders and Treatments
  • Photodynamic Therapy Research Studies
  • Nanoplatforms for cancer theranostics
  • Sperm and Testicular Function
  • Urologic and reproductive health conditions
  • Renal cell carcinoma treatment
  • Sexual Differentiation and Disorders
  • Adrenal and Paraganglionic Tumors
  • Cancer, Hypoxia, and Metabolism
  • Reproductive Biology and Fertility
  • Testicular diseases and treatments
  • Sarcoma Diagnosis and Treatment
  • Sexuality, Behavior, and Technology
  • Genital Health and Disease
  • Porphyrin and Phthalocyanine Chemistry
  • Infectious Disease Case Reports and Treatments
  • Ureteral procedures and complications
  • Pediatric Urology and Nephrology Studies
  • Reproductive Health and Technologies
  • Urinary Tract Infections Management

Nagano Red Cross Hospital
2015-2025

Creative Commons
2023

Weatherford College
2010-2013

Red Cross Hospital
2002

Kanazawa University
1986-1997

University of Occupational and Environmental Health Japan
1993

Harvard University
1988-1989

Massachusetts General Hospital
1988

Rossella Cannarella Rupin Shah Taha Abo-Almagd Abdel-Meguid Hamoda Florence Boitrelle Ramadan Saleh and 95 more Murat Gül Amarnath Rambhatla Parviz K. Kavoussi Tuncay Toprak ‬Ahmed M. Harraz Edmund Ko Gökhan Çeker Damayanthi Durairajanayagam Noora Alkhalidi Shinnosuke Kuroda Andrea Crafa Ralf Henkel Gianmaria Salvio Berk Hazır Mahsa Darbandi Marion Bendayan Sara Darbandi Marco Falcone Nicolás Garrido Raghavender Kosgi Raneen Sawaid Kaiyal Keshab Kumar Karna Nguyen Ho Vinh Phuoc Ponco Birowo Giovanni M. Colpi Jean de la Rosette Germar‐Michael Pinggera Quang Nguyen Armand Zini Wael Zohdy Singh Rajender Pallavi Saini Sidney Glina Haocheng Lin Taymour Mostafa César Rojas-Cruz Mohamed Arafa Aldo E. Calogero Fotios Dimitriadis Priyank Kothari Vilvapathy Senguttuvan Karthikeyan Keisuke Okada Koji Chiba Ateş Kadıoğlu Barış Altay Tahsin Turunç Birutė Žilaitienė Fatih Gökalp Aram Adamyan Darren Katz Eric Chung Tiago César Mierzwa Daniel Suslik Zylbersztejn Gustavo Marquesine Paul Nikolaos Sofikitis Ioannis Sokolakis Vineet Malhotra Sakti Ronggowardhana Brodjonegoro Ricky Adriansjah Akira Tsujimura Toshiyasu Amano Giancarlo Balercia Imad Ziouziou Isaac Ardianson Deswanto Marlon Martínez Hyun Jun Park Emre Bakırcıoğlu Erman Ceyhan Kaan Aydos Jonathan Ramsay Suks Minhas Manaf Al Hashimi Ramy Abou Ghayda Nicholas N. Tadros Puneet Sindhwani Christopher C.K. Ho Rinaldo Indra Rachman Marcelo Rodríguez Peña Ahmad Motawi A. Ponnusamy Satish Dipankar Azwar Amir Saleh Binsaleh Ege Can Şerefoğlu Ravi Banthia Kareim Khalafalla Ari Basukarno Bac Nguyen Hoai Karun Singla Rafael F. Ambar Konstantinos Makarounis Shivam Priyadarshi Gede Wirya Kusuma Duarsa Widi Atmoko Sunil Jindal

The purpose of this meta-analysis is to study the impact varicocele repair in largest cohort infertile males with clinical by including all available studies, no language restrictions, comparing intra-person conventional semen parameters before and after varicoceles.

10.5534/wjmh.230034 article EN cc-by-nc The World Journal of Men s Health 2023-06-27

Both glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth 2 (FGF2) are bona fide self-renewal factors for spermatogonial stem cells, whereas retinoic acid (RA) induces differentiation. In this study, we investigated the functional differences between FGF2 GDNF in germline niche by providing these using a drug delivery system vivo. Although both expanded GFRA1+ subset of undifferentiated spermatogonia, FGF2-expanded expressed RARG, which is indispensable proper...

10.1016/j.stemcr.2018.03.016 article EN cc-by-nc-nd Stem Cell Reports 2018-04-19

Testosterone affects several organs in the body and is very important for male well-being. Aging men with late-onset hypogonadism (LOH) experience physiologic, psychiatric, sexual symptoms related to a decline serum concentration of testosterone age. However, it well-known that extent does not correlate severity LOH-related symptoms. Therefore, difficult diagnose treat patients LOH. In addition, symptoms, response replacement therapy (TRT), medical insurance coverage differ among ethnicities...

10.4103/aja2024111 article EN cc-by-nc-sa Asian Journal of Andrology 2025-01-28

Introduction. Patients with late onset hypogonadism (LOH) also suffered from lower urinary tract symptoms (LUTS) and LOH symptoms. The objects of this study are to evaluate the efficacy testosterone replace therapy (TRT) by ointment (Glowmin: GL) for LUTS in patients.Methods. Aging Male Symptom (AMS) scale, Medical Outcomes Study (MOS) 36-Item Short-Form Health Survey (SF-36), International Index Erectile Function (IIEF-5) Prostate Score (IPSS) were obtained patients LOH. A total 41 have...

10.3109/13685538.2010.487552 article EN The Aging Male 2010-08-26

Tadalafil is a promising phosphodiesterase (PDE) 5 inhibitor prescribed for erectile dysfunction (ED). Daily low dose (5 mg) of tadalafil has also been used the treatment male lower urinary tract symptoms (LUTS) associated with benign prostate hyperplasia (BPH). PDE5 inhibitors induce relaxation smooth muscle cells in urethra, prostate, bladder neck, and blood vessels. The aim this study was to investigate efficacy on vessels endothelial function, patients LUTS BPH.The Institutional Review...

10.1080/13685538.2017.1367922 article EN The Aging Male 2017-08-22

No AccessJournal of Urology1 Feb 1988Intratumor Injection as a More Effective Means Porphyrin Administration for Photodynamic Therapy Toshiyasu Amano, George R. Prout, and Chi-Wei Lin AmanoToshiyasu Amano articles by this author , ProutGeorge Prout LinChi-Wei View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)42441-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail therapy (PDT) with hematoporphyrin derivative...

10.1016/s0022-5347(17)42441-4 article EN The Journal of Urology 1988-02-01

10.1007/s10147-010-0115-0 article EN International Journal of Clinical Oncology 2010-08-05

Objectives To determine the efficacy of two α1‐adrenoceptor antagonists with different affinities for subtypes, silodosin and naftopidil, in treatment premature ejaculation. Methods This was a prospective, open‐label, multicenter trial. A total 26 patients untreated acquired ejaculation were enrolled. Premature defined based on International Society Sexual Medicine recommendation. Patients self‐administered demand 4 mg or naftopidil 25 1 h before intercourse, alternating drugs at least three...

10.1111/iju.13392 article EN International Journal of Urology 2017-06-18

Background : A very rare case of retroperitoneal bleeding due to spontaneous rupture a large adrenal myelolipoma in 62‐year‐old woman is reported. Methods/Results She consulted the emergency room Nagano Red Cross Hospital with complaint sudden left flank pain. computerized tomography (CT) scan revealed tumor areas fat density and hematoma space. After her general condition improved, an operation was performed. The strongly adhered kidney nephrectomy curative. Histologic diagnosis...

10.1046/j.1442-2042.1999.611109.x article EN International Journal of Urology 1999-11-01

Transrectal ultrasonography was performed in 46 patients with hemospermia. Abnormal findings the prostate and seminal vesicles, including prostatic stones, benign hyperplasia, prostatitis, dilatation calculi of were observed 34 (73.9%). However, no malignant lesions found or vesicles. a useful noninvasive procedure to investigate causes Furthermore, transrectal could demonstrate latent diseases exclude malignancy vesicle

10.1159/000282655 article EN Urologia Internationalis 1994-01-01

Abstract Testosterone plays an important role in maintaining both physical and mental function. Age‐related testosterone depletion contributes to the development of angina, arteriosclerosis, obesity, metabolic syndrome, dementia, frailty, a range other conditions. A condition involving age‐related associated clinical symptoms is defined as late‐onset hypogonadism (LOH). LOH treated by replacement therapy. Indications for therapy are determined evaluating signs.

10.1111/iju.15160 article EN International Journal of Urology 2023-02-09

No AccessJournal of Urology1 Dec 1991Integral Laser Photodynamic Treatment Refractory Multifocal Bladder Tumors Katsusuke Naito, Haruo Hisazumi, Tadao Uchibayashi, Toshiyasu Amano, Akio Hirata, Kazuto Komatsu, Takeyuki Ishida, and Norio Miyoshi NaitoKatsusuke Naito More articles by this author , HisazumiHaruo Hisazumi UchibayashiTadao Uchibayashi AmanoToshiyasu Amano HirataAkio Hirata KomatsuKazuto Komatsu IshidaTakeyuki Ishida MiyoshiNorio View All Author...

10.1016/s0022-5347(17)38160-0 article EN The Journal of Urology 1991-12-01

In addition to hormone replacement therapy, non-hormonal particularly Japanese traditional herbal medicine (Kampo), has been used alleviate the various symptoms of female menopause. The efficacy and safety for male late-onset hypogonadism (LOH) are investigated.One hundred fifty-one patients with LOH were treated via administration medicine. most appropriate was administered according their pathogenic alteration. After 4 weeks, clinical evaluated based on improvement score simplified...

10.3109/13685530903536684 article EN The Aging Male 2010-02-09

Several studies have indicated that erectile dysfunction (ED) patients also suffer from lower urinary tract symptoms (LUTS). We investigated a group of men with LUTS and assessed their sexual function the aim being able to predict ED risk factors introduce treatments earlier for this patient group.International Prostate Symptom Score (IPSS), Overactive Bladder Symptoms (OABSS) Sexual Health Inventory Men (SHIM) score were obtained 236 at first out-patients visit. Clinical parameters such as...

10.3109/13685538.2015.1103219 article EN The Aging Male 2015-11-09
Ashok Agarwal Sajal Gupta Rakesh Sharma Renata Finelli Shinnosuke Kuroda and 89 more Sarah C. Vij Florence Boitrelle Parviz K. Kavoussi Amarnath Rambhatla Ramadan Saleh Eric Chung Taymour Mostafa Armand Zini Edmund Ko Neel Parekh Marlon Martínez Mohamed Arafa Nicholas N. Tadros Jean de la Rosette Tan V. Le Osvaldo Rajmil Hussein Kandil Gideon Blecher Giovanni Liguori Ettore Caroppo Christopher C.K. Ho Andrew Altman Petar Bajic David A. Goldfarb Bradley Gill Daniel Suslik Zylbersztejn Juan Manuel Corral Molina Marcello Gava João Paulo Cardoso Raghavender Kosgi Gökhan Çeker Birutė Žilaitienė Edoardo Pescatori Edson Borges Gede Wirya Kusuma Duarsa Germar‐Michael Pinggera Gian Maria Busetto Giancarlo Balercia Giorgio Franco Gökhan Çalık Hassan Sallam Hyun Jun Park Jonathan Ramsay Juan G. Álvarez Kareim Khalafalla Kasonde Bowa Lukman Hakim Mara Simopoulou Marcelo Gabriel Rodriguez Marjan Sabbaghian Haitham Elbardisi M. Timpano Mesut Altan Mohamed Elkhouly Mohamed S. Al‐Marhoon Mohammad Ali Sadighi Gilani Mohammad Ayodhia Soebadi Mohammad Hossein Nasr‐Esfahani Nicolás Garrido Paraskevi Vogiatzi Ponco Birowo Premal Patel Qaisar Javed Rafael F. Ambar Ricky Adriansjah Sami Alsaid S. Mičić Sheena E. M. Lewis Shingai Mutambirwa Shinichiro Fukuhara Sijo Parekattil Sun Tae Ahn Sunil Jindal Teppei Takeshima A Puigvert Toshiyasu Amano Trenton Barrett Tuncay Toprak Vineet Malhotra Widi Atmoko Yasushi Yumura Yoshiharu Morimoto Thiago Fernandes Negris Lima Yannic Kunz Yuki Kato Yukihiro Umemoto Giovanni M. Colpi Damayanthi Durairajanayagam Rupin Shah

The success of vasectomy is determined by the outcome a post-vasectomy semen analysis (PVSA). This article describes step-by-step procedure to perform PVSA accurately, report data from patients who underwent post between 2015 and 2021 experience, along with results an international online survey on clinical practice. We present detailed protocol for performing interpretating testing, recommendations proficiency competency assessment PVSA, laboratory scenarios. Moreover, we conducted 1,114...

10.5534/wjmh.210191 article EN cc-by-nc The World Journal of Men s Health 2022-01-01

The aim of this study is to clarify the relationship erectile dysfunction (ED) and diabetes mellitus (DM) parameters (referred with '1'), including peripheral neuropathy '2').(1) DM age, serum levels blood sugar, hemoglobin A1c, duration number complications were obtained from 145 patients at a general clinic. (2) examinations by vibration perception threshold (VPT) Achilles tendon reflex performed in 97 patients. Erectile functions evaluated International Index Function (IIEF 5). patients'...

10.1159/000327991 article EN Urologia Internationalis 2011-01-01

No AccessJournal of Urology1 Aug 1990A Combined Therapy Hyperthermia and Tumor Necrosis Factor for Nude Mice Bearing KK-47 Bladder Cancer Toshiyasu Amano, Kazuto Kumini, Kazuyoshi Nakashima, Tadao Uchibayashi, Haruo Hisazumi AmanoToshiyasu Amano More articles by this author , KuminiKazuto Kumini NakashimaKazuyoshi Nakashima UchibayashiTadao Uchibayashi HisazumiHaruo View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)39463-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack...

10.1016/s0022-5347(17)39463-6 article EN The Journal of Urology 1990-08-01

The purpose of this study was to investigate andrological aspects, including male infertility and androgen deficiency, after treatments bilateral testicular tumors.Five subjects with cancer were clinically analyzed between April 1996 March 2013.The mean age at initial treatment 29.4 ± 3.3 years old. In the 4 metachronous cases, a contralateral tumor occurred 79.0 50.0 months. Histologically, seminoma in 3 cases nonseminoma combined 2 cases. All underwent orchiectomy, additional chemotherapy,...

10.1007/s12522-013-0171-z article EN cc-by-nc-nd Reproductive Medicine and Biology 2013-11-04

Introduction: It is well known that there a reduction of circadian rhythm in blood testosterone levels with aging. Our previous report revealed 3 mg short-acting ointment (Glowmin: GL) elevated serum to within the physiological range for 4–6 h. The aim this study was clarify clinical efficacy and safety GL used topically once every morning, enhance testosterone, late-onset hypogonadism (LOH).Methods: A total 61 LOH patients received day morning on scrotal skin 24 weeks. evaluated by aging...

10.1080/13685538.2018.1471129 article EN The Aging Male 2018-05-08
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