Mara Simopoulou

ORCID: 0000-0002-1000-9100
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Reproductive Health and Technologies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Sperm and Testicular Function
  • Reproductive System and Pregnancy
  • Endometriosis Research and Treatment
  • Prenatal Screening and Diagnostics
  • Gynecological conditions and treatments
  • Sexual function and dysfunction studies
  • COVID-19 Impact on Reproduction
  • Pregnancy and preeclampsia studies
  • MicroRNA in disease regulation
  • Olfactory and Sensory Function Studies
  • Pregnancy and Medication Impact
  • Global Maternal and Child Health
  • Animal Genetics and Reproduction
  • Sexual Differentiation and Disorders
  • Ectopic Pregnancy Diagnosis and Management
  • Meta-analysis and systematic reviews
  • Pluripotent Stem Cells Research
  • Testicular diseases and treatments
  • Demographic Trends and Gender Preferences
  • Academic Publishing and Open Access
  • Carcinogens and Genotoxicity Assessment

National and Kapodistrian University of Athens
2016-2025

Center for Human Reproduction
2020

Aretaeio Hospital
2017-2020

University of Thessaly
2020

Democritus University of Thrace
2004-2013

National Centre of Scientific Research "Demokritos"
2013

University College London
2000-2003

Since the introduction of autologous platelet-rich plasma (PRP) in medical practice, various studies have documented that implementing PRP can enhance healing and anti-aging process, employing angiogenesis regeneration due to multiple growth factors cytokines involved. Numerous reports shown promising results with use ovarian treatment, regarding reactivation folliculogenesis. This case series on two women premature failure (POF) aged 40 27 years, respectively, one menopausal woman 46 years....

10.1177/0963689719859539 article EN cc-by-nc Cell Transplantation 2019-07-04

Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting clinical routine practice is imperative. This study aims provide pilot data regarding PRP application for rejuvenation. Four studies were conducted poor response (POR), premature insufficiency (POI), perimenopause, and menopause, respectively. Each reports thirty patients, 120 participants recruited total. All provided...

10.3390/jcm9061809 article EN Journal of Clinical Medicine 2020-06-10

This report presents the case of a woman aged 40 who has experienced premature menopause from age 35. Having rejected oocyte donation, she opted for intraovarian injection autologous platelet-rich plasma with aim to rejuvenate ovarian tissue and enable employment her own gametes through in-vitro fertilization. Six weeks following treatment, significant reduction in patient's follicle-stimulating hormone (FSH) levels were noted. A natural fertilization cycle led biochemical pregnancy,...

10.3390/jcm8010001 article EN Journal of Clinical Medicine 2018-12-20

Poor responders are described as those In Vitro Fertilization (IVF) patients who failing to respond controlled ovarian stimulation protocols. Extensive research has focused on crafting the optimal treatment. However, it appears that each approach fails be established effective or guaranteed towards successful management. Platelet-Rich Plasma (PRP) is a novel, highly promising been successfully applied for an array of medical issues. this case series, we present 3 poor responder with common...

10.1159/000491697 article EN Gynecologic and Obstetric Investigation 2018-08-22

Glyphosate is the active ingredient of Roundup®, which one most popular herbicides worldwide. Although many studies have focused on reproductive toxicity glyphosate or glyphosate-based herbicides, majority them concluded that effect specific herbicide negligible, while only a few indicate male alone. The aim present study was to investigate 0.36 mg/L sperm motility and DNA fragmentation (SDF). Thirty healthy men volunteered undergo semen analysis for purpose study. Sperm calculated according...

10.3390/ijerph15061117 article EN International Journal of Environmental Research and Public Health 2018-05-30

Background/Aim: Patients diagnosed with chronic endometritis (CE) may fail to respond standard antibiotic treatment. The driver behind the approach reported here was imperative need for alternative therapeutic solutions. Case Report: This case report presents a woman CE and premature ovarian insufficiency having experienced repeated implantation failures following donated embryo transfers. patient through hysteroscopy, microbiological analysis scanning electron microscopy. Following...

10.21873/invivo.11504 article EN In Vivo 2019-01-01

Preimplantation genetic diagnosis (PGD) is usually performed on cleavage stage embryos day 3 post-insemination. Fluorescent in situ hybridization (FISH) has revealed four groups of chromosome patterns at this stage: uniformly normal, abnormal, mosaic and chaotic. Recently, some vitro fertilization (IVF) clinics have started to perform blastocyst transfer. In blastocysts, conventional karyotyping shown that all are observed. the present study, were cultured 5 subject a two-round multicolour...

10.1002/1097-0223(200007)20:7<552::aid-pd871>3.0.co;2-f article EN Prenatal Diagnosis 2000-07-01

Abstract Background Peri‐implantitis treatments are mainly based on protocols for teeth but have not shown favorable outcomes implants. The potential role of titanium dissolution products in peri‐implantitis necessitate the consideration material properties devising treatment protocols. We assessed implant cleaning interventions (1) bacterial removal from Ti‐bound biofilms, (2) Ti surface alterations and related particle dissolution, (3) cytocompatibility. Methods Acid‐etched discs were...

10.1002/jper.20-0186 article EN Journal of Periodontology 2020-09-02
Ala’a Farkouh Ashok Agarwal Taha Abo-Almagd Abdel-Meguid Hamoda Parviz K. Kavoussi Ramadan Saleh and 95 more Armand Zini Mohamed Arafa ‬Ahmed M. Harraz Murat Gül Vilvapathy Senguttuvan Karthikeyan Damayanthi Durairajanayagam Amarnath Rambhatla Florence Boitrelle Eric Chung Ponco Birowo Tuncay Toprak Ramy Abou Ghayda Rossella Cannarella Nguyen Ho Vinh Phuoc Fotios Dimitriadis Giorgio Ivan Russo Ioannis Sokolakis Taymour Mostafa Konstantinos Makarounis Imad Ziouziou Shinnosuke Kuroda Marion Bendayan Raneen Sawaid Kaiyal Andrian Japari Mara Simopoulou Lucia Rocco Nicolás Garrido Nazim Gherabi Kadir Böcü Oğuzhan Kahraman Tan V. Le Christine Wyns Kelton Tremellen Selçuk Sarıkaya Sheena E. M. Lewis Donald P. Evenson Edmund Ko Aldo E. Calogero Fahmi Bahar Marlon Martínez Andrea Crafa Quang Nguyen Rafael F. Ambar Giovanni M. Colpi Emre Bakırcıoğlu Ralf Henkel Hussein Kandil Ege Can Şerefoğlu Abdullah Alarbid Akira Tsujimura Alireza Kheradmand Christina Anagnostopoulou Angelo Marino Aram Adamyan Birutė Žilaitienė Cevahir Özer Edoardo Pescatori Paraskevi Vogiatzi Gian Maria Busetto Giancarlo Balercia Haitham Elbardisi Hamed Akhavizadegan Hesamoddin Sajadi Hisanori Taniguchi Hyun Jun Park Israel Maldonado Rosas Mohamed S. Al‐Marhoon Mohammad Ali Sadighi Gilani Naif Alhathal Germar‐Michael Pinggera Priyank Kothari Nasser Mogharabian S. Mičić Sheryl T. Homa Sara Darbandi Tran Quang Tien Long Wael Zohdy Widi Atmoko Marjan Sabbaghian Wael Ibrahim Ryan P. Smith Christopher C.K. Ho Jean de la Rosette Ahmed I. El‐Sakka Mirko Preto Cătălina Zenoaga-Barbăroșie Saad Abumelha Aykut Başer Kaan Aydos Liliana Berenice Ramirez Dominguez Vijay Kumar Teng Aik Ong Tiago César Mierzwa Ricky Adriansjah Saleem Ali Banihani

Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose this study was to investigate global practices related the management elevated SDF in infertile men, summarize relevant professional society recommendations, provide expert recommendations for managing condition.An online survey on clinical disseminated clinicians, according CHERRIES checklist criteria. Management protocols various conditions were...

10.5534/wjmh.230008 article EN cc-by-nc The World Journal of Men s Health 2023-01-01

This study investigated the serum levels of resistin, adiponectin and leptin during physiological menstrual cycle. Sixteen women (age: 19-30 years; body mass index: 19.46-24.9) with regular cycles participated. Fasting blood samples were collected on alternate days throughout a full Mean resistin concentrations slightly higher luteal phase (5.30+/-0.23 ng/ml) compared to follicular (4.68+/-0.07 midcycle (4.86+/-0.09 phases (p=0.032). (18.14+/-0.28 significantly lower (21.79+/-0.29 ng/ml,...

10.1507/endocrj.k08e-222 article EN Endocrine Journal 2009-01-01
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