A5090253800- COVID-19 Clinical Research Studies
- Gut microbiota and health
- Bacteriophages and microbial interactions
- SARS-CoV-2 and COVID-19 Research
- Calcium signaling and nucleotide metabolism
- Clostridium difficile and Clostridium perfringens research
- Dysphagia Assessment and Management
- Erythrocyte Function and Pathophysiology
- Dermatological and COVID-19 studies
- Diabetes and associated disorders
- Birth, Development, and Health
- Respiratory Support and Mechanisms
- Thermal Regulation in Medicine
- Health and Lifestyle Studies
- COVID-19 and healthcare impacts
- Parkinson's Disease Mechanisms and Treatments
- Child Nutrition and Feeding Issues
- Obesity, Physical Activity, Diet
- Chronic Lymphocytic Leukemia Research
- Dietary Effects on Health
- Gastrointestinal motility and disorders
Royal Free London NHS Foundation Trust
2023
Royal Brompton Hospital
2023
The Royal Free Hospital
2023
University College London
2023
University of Florida
2019-2022
Florida College
2019
Teaching Hospital Kandy
2017
We performed a study to (i) investigate efficacy of an Escherichia coli/Salmonella spp./Listeria monocytogenes-targeting bacteriophage cocktail (tentatively named F.O.P.) reduce human pathogenic E. coli strain O157:H7 in experimentally infected mice, and (ii) determine how bacteriophages impact the normal gut microbiota when compared with antibiotic therapy. A total 85 mice were inoculated Ec231 [nalidixic acid resistant (NalAcR)] via oral gavage, randomized into six groups separated three...
Polyphenol-rich cranberry extracts decrease intestinal inflammation, alter gut microbiota, and permeability in obese mice, but the effect has not been investigated adults who are obese. The purpose of this randomized double-blind, cross-over feeding study (BMI = 37.4 ± 1.2 kg/m2) otherwise healthy (n 36) 35.4 1.3 years was to determine effects consuming 480 mL a high polyphenolic or control beverage daily for 2 weeks on gastrointestinal permeability, markers inflammation immune function,...
Acute lung injury in COVID-19 results diffuse alveolar damage with disruption of the alveolar-capillary barrier, coagulation activation, fibrin deposition and pulmonary capillary thrombi. Nebulized recombinant tissue plasminogen activator (rt-PA) has potential to facilitate localized thrombolysis compartment improve oxygenation. In this proof-of-concept safety study, adults COVID-19-induced respiratory failure a <300 mmHg PaO
Nebulized thrombolysis offers locally targeted therapy with potentially lower bleeding risk than systemic administration for coronavirus disease 2019 (COVID-19) respiratory failure. In a proof-of-concept safety study, adult patients COVID-19-induced failure and &lt;300mmHg PaO2/FiO2 (P/F) ratio, requiring invasive mechanical ventilation (IMV) or non-invasive support (NIRS) received nebulized rt-PA in two cohorts (C1 C2), alongside standard of care during the first UK COVID-19 waves....
The Journal of the Postgraduate Institute Medicine (JPGIM) is an open access, peer-reviewed, biannual journal published by (PGIM) University Colombo (UOC), Sri Lanka. JPGIM aims to publish articles relevant clinicians, policymakers, and researchers on topics relating practice medicine, medical education, professionalism, integrity, ethics research enterprise. has been in publication since 2014 publishes accepted manuscripts online immediately after copy-editing, enabling rapid dissemination...