A5088422856- Gut microbiota and health
- Gastrointestinal motility and disorders
- Parkinson's Disease Mechanisms and Treatments
- Dysphagia Assessment and Management
- Probiotics and Fermented Foods
- Pediatric health and respiratory diseases
- Immune Cell Function and Interaction
- Diet and metabolism studies
- Health, psychology, and well-being
- Child Nutrition and Feeding Issues
- Microbial Metabolites in Food Biotechnology
- Herbal Medicine Research Studies
- Respiratory Support and Mechanisms
- Helicobacter pylori-related gastroenterology studies
- Nutrition and Health in Aging
- Food composition and properties
- Allergic Rhinitis and Sensitization
- Antioxidant Activity and Oxidative Stress
- Infant Health and Development
- Asthma and respiratory diseases
- Infant Nutrition and Health
- Therapeutic Uses of Natural Elements
- Acupuncture Treatment Research Studies
- Pressure Ulcer Prevention and Management
- Consumer Attitudes and Food Labeling
University of Florida
2012-2024
Newell Brands (United States)
2016-2019
Unité de Nutrition Humaine
2012
Hospital de León
2006
Universitat de Barcelona
2006
Background: Mushrooms are widely cited for their medicinal qualities, yet very few human intervention studies have been done using contemporary guidelines.Objective: The aim of this study was to determine whether consumption whole, dried Lentinula edodes (shiitake) mushrooms could improve immune function. Primary objectives were ascertain L. would γδ-T cell proliferation and activation responses, quantify a dose response, elicit cytokine secretion patterns. Secondary included determining...
Objective: This study determined whether older adults who consumed a probiotic mixture would have greater proportion of circulating CD4+ lymphocytes, altered cytokine production, and shift in intestinal microbiota toward healthier microbial community.
Acute psychological stress is positively associated with a cold/flu. The present randomised, double-blind, placebo-controlled study examined the effect of three potentially probiotic bacteria on proportion healthy days over 6-week period in academically stressed undergraduate students ( n 581) who received Lactobacillus helveticus R0052, Bifidobacterium longum ssp. infantis R0033, bifidum R0071 or placebo. On each day, participants recorded intensity (scale: 0 = not experiencing to 3 very...
Introduction: Non-motor symptoms of Parkinson's disease (PD) such as gastrointestinal (GI) dysfunction are common, yet little is known about how modifying dietary intake impacts PD symptoms. The aim this study in individuals with was to determine whether a Mediterranean diet intervention feasible and affects GI function, intestinal permeability fecal microbial communities. Methods: A single-arm, 5-week conducted eight people PD. Daily weekly questionnaires were administered changes Urine...
Microbial metabolism in the gut may alter human bile acid a way that beneficially affects lipid homeostasis and therefore cardiovascular disease risk. Deconjugation of acids by microbes is thought to be key this mechanism but has yet characterised blood stool while observing markers. The aim study was determine effect 3 different probiotic strains on plasma context glucose metabolism. In 18-week, randomised, double-blind crossover study, healthy adults (53±8 years) with high waist...
Psychological stress is associated with gastrointestinal (GI) distress. This secondary analysis from a randomised, double-blind, placebo-controlled study examined whether three different probiotics could normalise self-reported stress-associated GI discomfort and reduce overall stress. Undergraduate students (n=581) received Lactobacillus helveticus R0052, Bifidobacterium longum ssp. infantis R0033 , bifidum R0071, or placebo. Participants 2 outcomes for 6-week period, which included final...
γδ T cells are important immune surveillance residing in epithelial layers lining the intestine, lung, and reproductive tract. The main objective of this study was to test hypothesis that consumption dietary compounds from grapes would modify T-cell function. Other factors related function after grape juice were also tested. A randomized, double-blind, placebo-controlled, parallel intervention conducted: 100% made Concord or a placebo beverage consumed by 85 individuals daily for 9 weeks....
Abstract Background Healthy individuals may experience increases in intestinal permeability after chronic or acute use of non-steroidal anti-inflammatory drugs, which be attenuated by probiotics. This study investigates the effects an aspirin challenge on gastroduodenal barrier function with without prophylactic probiotic consumption. Methods Twenty-nine generally healthy participants (26 ± 6 years) completed a 14-week randomized, double-blind, crossover trial. A containing 2 Lactobacilli...
Parkinson’s disease is associated with gastrointestinal (GI) dysfunction, including constipation symptoms and abnormal intestinal permeability inflammation. A Mediterranean diet (MediDiet) may aid in management. This parallel, randomized, controlled trial people (PwP) compared a MediDiet against standard of care on change symptoms, dietary intake, fecal zonulin calprotectin concentrations as markers inflammation, respectively. Participants were randomized to either for (control; n = 17, 65.1...
Background: Malnutrition is prevalent in elders with pressure ulcers and associated increased morbidity mortality. This study compared nutritional status, assessed by the Mini Nutrition Assessment (MNA), to immune function nursing home ulcers. Methods: Nutritional status was residents (>65 years) a stage II or more severe ulcer. Subjects were classified as well nourished, at risk of malnutrition, malnourished according MNA score. Blood drawn assess whole blood mitogen‐induced lymphocyte...
Few health-related quality of life (QOL) questionnaires are designed specifically for healthy populations and specific to gastrointestinal (GI) symptoms even though individuals may frequently experience gas, bloating, constipation, diarrhea, abdominal pain. The purpose this study was develop validate a tool that could assess the impact GI on digestion-associated QOL in otherwise individuals.After review current literature with input from experienced researchers, 24-item questionnaire...
Glutamic acid decarboxylase (GAD), the enzyme that catalyzes conversion of glutamate to γ-aminobutyric (GABA), is expressed in GABA-secreting neurons and pancreatic β cells.1 Anti-GAD antibodies (GAD Abs) have been described patients with type 1 diabetes mellitus two CNS disorders, stiff-person syndrome cerebellar ataxia associated polyendocrine autoimmunity.2 We report a patient paraneoplastic encephalomyelitis tumor GAD Abs. A 67-year-old man presented paresthesias numbness hands, feet,...
Constipation is a common and sometimes debilitating non-motor symptom of Parkinson's disease (PD) that can result in intestinal inflammation microbial dysbiosis. The Mediterranean diet, rich fermentable fibres anti-inflammatory phenolic compounds, associated with reduced risk developing PD slower progression parkinsonism. diet often recommended for people PD; however, no studies to date examine this as therapeutic intervention modulate gastrointestinal (GI) dysfunction.This randomised,...
Polyphenol-rich cranberry extracts decrease intestinal inflammation, alter gut microbiota, and permeability in obese mice, but the effect has not been investigated adults who are obese. The purpose of this randomized double-blind, cross-over feeding study (BMI = 37.4 ± 1.2 kg/m2) otherwise healthy (n 36) 35.4 1.3 years was to determine effects consuming 480 mL a high polyphenolic or control beverage daily for 2 weeks on gastrointestinal permeability, markers inflammation immune function,...
The aim of this work was to determine the bioavailability herbs and spices after human consumption by measuring ability protect lymphocytes from an oxidative injury examining impact on inflammatory biomarkers in activated THP-1 cells.
This randomized, placebo-controlled, double-blind, parallel trial investigated whether generally healthy adult, nonelite runners would have a greater time-to-exhaustion during submaximal treadmill running with probiotic versus placebo supplementation. It was hypothesized that the impact training progression by reducing gastrointestinal (GI) and cold/flu symptoms. Participants who typically ran ≥24 km/week, or cross-trained 3–5 days per week, had maximal oxygen intake (V̇O 2 max) in 60–85th...
Background: Therapeutic or pharmacologic doses of arginine are used to enhance blood flow and immune function despite the lack dose‐response studies potential for adverse effects. This study determined optimal level oral supplementation required elevate serum concentrations yet limit effects in healthy endotoxemic mice. Methods: Male CB6F1 mice were fed one following diets: The standard AIN93G (3 g arginine/100 protein) this diet modified provide 10 g, 20 30 protein. On day 14, injected with...