A5067166009- Hepatitis B Virus Studies
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Brucella: diagnosis, epidemiology, treatment
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- Antibiotic Resistance in Bacteria
- Leptospirosis research and findings
- Antibiotic Use and Resistance
- Tuberculosis Research and Epidemiology
- Burkholderia infections and melioidosis
- HIV-related health complications and treatments
- Salmonella and Campylobacter epidemiology
- Hemoglobinopathies and Related Disorders
- Drug-Induced Hepatotoxicity and Protection
- Infectious Diseases and Tuberculosis
- Iron Metabolism and Disorders
- Orthopedic Infections and Treatments
- COVID-19 diagnosis using AI
- RNA Interference and Gene Delivery
- Pneumonia and Respiratory Infections
Kermanshah University of Medical Sciences
2016-2025
Imam Reza Hospital
2008-2025
Babol University of Medical Sciences
2022
Tehran University of Medical Sciences
2013
Abstract Background COVID‐19 patients, especially the patients requiring hospitalisation, have a high risk of several complications such as opportunistic bacterial and fungal infections. Mucormycosis is rare infection that mainly affects diabetic immunocompromised patients. An increase has been observed in number rhino‐orbital mucormycosis with admitted to Imam Khomeini Hospital, Kermanshah, Iran, since October 2020. This report frequency, factors, clinical manifestations, treatment...
Since the first official report of SARS-CoV-2 infection in Iran on 19 February 2020, our country has been one worst affected countries by COVID-19 epidemic Middle East. In addition to demographic and clinical characteristics, number hospitalized cases deaths is an important factor for evidence-based decision-making disease control preparing healthcare system face future challenges COVID-19. Therefore, this cohort study was conducted determine demographics, outcomes patients Kermanshah...
Abstract Objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. The majority of patients experience asymptomatic to mild self-limited disease, but some cases progress and multi-organ failure. However, so far, no approved antiviral therapy has been available treatment COVID-19. Sofosbuvir/velpatasvir (SOF/VEL) an anti-HCV drug that capable suppressing other families positive-sense RNA viruses with conserved polymerase may be effective...
The combination of sofosbuvir and daclatasvir is a potent, pangenotypic regimen suitable for mass-scale hepatitis C treatment, especially in resource-limited countries where newer, expensive combinations are not available. This has been widely tested on genotype 4. However, Phase III trials this other genotypes have cost prohibitive. With the introduction generic, low-cost daclatasvir, large-scale studies now possible.Sofosbuvir at 400 mg 60 were coformulated into fixed-dose (FDC) tablet...
Infection with coronavirus disease 2019 (COVID-19) could be complicated coagulopathy and high risk of thromboembolic events.The main aim the present study was to find coagulation profile intensive care unit (ICU) admitted patients COVID-19 from Kermanshah, Islamic Republic Iran.Coagulation parameters were analyzed using appropriate methods in 74 (24 aged <60 years 50 ≥60 years) compared 35 survivors (severe COVID-19) 39 non-survivors historically ICU.Forty-two percent had abnormal...
Introduction: Brucellosis is a common global zoonotic disease with wide range of complex and nonspecific clinical manifestations that may lead to misdiagnosis delayed treatment. Osteoarticular involvement the most complaint in brucellosis. Objective: This present study aims describe laboratory characteristics treatment brucellosis patients arthritis sacroiliitis. Methods: retrospective descriptive was performed on presenting teaching hospital Kermanshah, Iran diagnosis from 2011 2019. The...
Summary Mutations within the coding region of hepatitis B surface antigen ( HB s A g) have been found naturally in chronic carriers. To characterize mutations g from Iranian carriers who were vaccine and/or medication naive. The genes 360 patients amplified and directly sequenced. distribution amino acid substitutions was classified according to different immune epitopes protein. All isolates belonged genotype D . 222 (61.6%) contained at least one substitution. 404 (74.5%) 542 changes...
Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, development drug resistance is a major limitation to their long-term effectiveness.The aim this study was characterize reverse transcriptase (RT) protein variations among Iranian HBV carriers who did not receive any antiviral treatments.Hepatitis partial RT genes from 325 in active carrier patients were amplified directly sequenced. Nucleotide/amino acid...
Dear Editors The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for disease 2019 (COVID-19). clinical characteristics of COVID-19 pandemic announced by the World Health Organization (WHO) in March 20201 may be presented a form pneumonia some patients (10%-15%) which might progress toward distress syndrome, multi-organ failure and death.2 laboratory provides important information related to diagnosis, prognosis, response therapy.3 In severely affected with...
This research aimed to evaluate the specific microRNA (miRNA) including miR-17-5p, miRN-140-3p miR-191-5p, miR-200c-3p, and miR-N367 cellular factors (p21, SDF-1, XCL1, CCL-2, IL-2) in controlling replication of human immunodeficiency virus (HIV) ECs.The expression miRNAs was assessed between healthy control groups patient ART-naïve HIV, HIV ART, ECs, coinfection (HIV-HBV HIV-HCV) via real-time PCR technique. Besides, level nef gene were by ELISA method. The differences selected study...
Gastroenteritis refers to an infection in the stomach and small intestine that may be caused by bacteria, viruses, other pathogenic agents. Most strains of Escherichia coli (E. coli) gastrointestinal system have shared a symbiotic relationship with humans, but some serotypes are pathogenic. This study aimed identify E. pathotypes isolated from stool samples determine antibiotic resistance profiles these west Iran.