A5028215032- Zebrafish Biomedical Research Applications
- Autophagy in Disease and Therapy
- Sirtuins and Resveratrol in Medicine
- Calcium signaling and nucleotide metabolism
- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Physiological and biochemical adaptations
- Stress Responses and Cortisol
- Pharmacological Effects and Assays
- Sphingolipid Metabolism and Signaling
- Neonatal and fetal brain pathology
- Environmental Toxicology and Ecotoxicology
- Tryptophan and brain disorders
- Neuroendocrine regulation and behavior
Community University of Chapecó Region - Unochapecó
2019-2023
The increase in proinflammatory cytokine expression causes behavioral changes consistent with sickness behavior, and this led to the suggestion that depression might be a psychoneuroimmunological phenomenon. Here, we evaluated effects of pretreatment fluoxetine (10 mg/kg, i.p.) curcumin (0.5 on immune response elicited by inoculation an Aeromonas hydrophila bacterin zebrafish. Non-pretreated but A. hydrophila-inoculated sham-inoculated groups fish served as controls. social preference,...
Abstract Seizure is one of the most frequent neurological emergencies among neonates. Seizures during neurodevelopment could promote epileptogenesis by triggering inflammatory cascades and potentiating mTOR signaling. Epileptogenesis contemplates disrupted neurogenesis neurodegeneration; culminates in epilepsy. Epileptic patients suffer from unpredictable recurrent seizures, which lead to social, psychological, cognitive impairment. In this context, developing efficient treatments manage...