A5033803896- Metabolism and Genetic Disorders
- Animal Nutrition and Physiology
- Adipose Tissue and Metabolism
- Phase-change materials and chalcogenides
- Muscle metabolism and nutrition
- Clinical Nutrition and Gastroenterology
- Reproductive Physiology in Livestock
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Fatty Acid Research and Health
- Meat and Animal Product Quality
- Pharmacological Effects and Assays
- Glass properties and applications
- Infant Nutrition and Health
- Folate and B Vitamins Research
- Amino Acid Enzymes and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Biochemical and Molecular Research
- Nonlinear Optical Materials Studies
- Ruminant Nutrition and Digestive Physiology
- Diet and metabolism studies
- Animal Behavior and Welfare Studies
- Veterinary Medicine and Surgery
- RNA and protein synthesis mechanisms
- Essential Oils and Antimicrobial Activity
HUN-REN Institute for Nuclear Research
2021-2024
University of Debrecen
2008-2020
University of Sopron
2012
Teva Pharmaceuticals (Israel)
2002
Rappaport Family Institute for Research in the Medical Sciences
2002
University of Göttingen
1982-1998
University of Veterinary Medicine Hannover, Foundation
1991-1993
Hochschule Hannover
1991-1993
Washington University in St. Louis
1981-1989
Ontario Institute for Cancer Research
1975-1979
Carbamate derivatives of N-propargylaminoindans (Series I) and N-propargylphenethylamines II) were synthesized via multistep procedures from the corresponding hydroxy precursors. The respective rasagiline- selegiline-related series designed to combine inhibitory activities both acetylcholine esterase (AChE) monoamine oxidase (MAO) by virtue their carbamoyl propargylamine pharmacophores. Each compound was tested for these in vitro order find molecules with similar potencies against each...
Cholesterol uptake and efflux are key metabolic processes associated with macrophage physiology atherosclerosis. Peroxisome proliferator-activated receptor gamma (PPARγ) liver X alpha (LXRα) have been linked to the regulation of these processes. It remains be identified how activation receptors is connected regulated by endogenous lipid molecules. We CYP27, a p450 enzyme, as link between retinoid, PPARγ, LXR signaling. show that human CYP27 gene under coupled retinoids ligands PPARs via...
Most reports of Aboriginal tooth wear have been descriptive, and few dealt with the question rate. This study records cusp heights dental casts taken from individuals during a growth children ages six to 18. Their rates were greater than those Europeans, most rapid rate was recorded among males. These differences are due quantity dietary abrasives.
Five healthy males volunteered to exercise for 20 min on a motor-driven treadmill at five submaximal intensities (30, 45, 60, 75, and 90% of VO2 max). Peripheral venous blood samples were drawn from an indwelling catheter prior 9, 14, 19 each bout. Blood assayed whole-blood hemoglobin, total plasma protein concentrations, hematocrit, with water concentration calculated these values. The the electrolytes sodium (Na+), potassium (K+), calcium (Catot), ionized (Ca2+), chloride (Cl-), inorganic...
<i>Background/Aims:</i> In our previous study, impaired visually evoked flow velocity response was demonstrated in young chronic smokers. Our aim to study whether cerebrovascular reactivity is reversible 6–18 months after smoking cessation. <i>Methods:</i> Flow changes, by visual stimulus, were recorded the posterior cerebral arteries 15 smokers, former smokers and nonsmokers. The stimulation protocol consisted of 10 cycles with a resting phase 20 s (baseline)...
The annual plant anise (Pimpinella anisum L.), grown in Alberta over five consecutive seasons, was rated as medium for its herb vigor and growth, the yield quality of essential oil determined. average steam-distilled oil, calculated on a dry weight basis, 1.05–1.1% seed 1.2–1.35% whole crushed plant. number identified constituents, determined by using TL-GL-chromatography method, 16 plant, 12 with corresponding percentages 74.7 84.6, respectively. only major constituent trans-anethole which...
Zusammenfassung Zwei 4jährigen veredelten Landschwein‐Sauen wurde während der Gravidität und Laktation eine konstante Tagesration gefüttert, welche 21,94 g P/Tag enthielt. In Mitte am Ende Gravidität, Anfang wurden nach parenteraler Verabreichung von P 32 aus dem Verhältnis spezifischen Aktivitäten Kot Harn endogener Kot‐P, exogener absorbierter Futter‐P wahre Verdaulichkeit des beredinet. Daneben die P‐Ausscheidungen in Milch bestimmt P‐Bilanz errechnet. Es ein Ansteigen wahren bis zum 31%...
Smoking has been known to cause endothelial dysfunction and is an important risk factor for ischemic stroke. In our study we investigated whether chronic cigarette smoking affects the cerebral blood flow velocity response a physiological, visual stimulus. By using cortex stimulation paradigm, in posterior arteries (PCA) was measured bilaterally, 32 young healthy adults (16 smokers, 16 nonsmokers). The protocol consisted of 10 cycles with resting phase 20s stimulating 40s each cycle. Besides...
The metabolization of DL-methionine and a hydroxy analogue form, DL-MHA-Ca, was studied by means 14C-labelled substances. For this purpose 60 male day-old chicks were administered 1-14C-labelled substances DL-MHA-Ca into the birds' crop. In 20 birds 14CO2 activity excretion with expired air measured for period 24 hours post administration radiorespirometry. killed 24, 48 72 14C-activity determined in following fractions: excrements, gastrointestinal contents, digestive tract, blood, kidney,...
The concentration of leucine in the growth medium has been found to influence expression temperature sensitive phenotype a mutant Chinese hamster ovary cells with an altered leucyl-tRNA synthetase. Plating efficiency and studies showed that increasing allows survive at normally non-permissive high temperatures conversely decreasing enhances adverse effectsof temperature. A similar but smaller effect was noted isoleucine. It is suggested this observation may form basis rapid test, useful...
Bei zwei Sauen wurde der Ca-, P- und N-Umsatz bei konstanter Fütterung in Mitte am Ende Graviditat Anfang Laktation täglich untersucht. Die Tagesration enthielt 21,94 g P, 23,18 Ca 102,6 N. Außerdem wurden mit dem Tränkwasser 1,1 bis 2,7 zugeführt. In Kot, Harn Milch Ca, P N bestimmt die Bilanzen für jeden einzelnen Tag errechnet. Auch intestinale P-Absorption -Exkretion bestimmt. Untersuchungen sollten zur Klärung Frage beitragen, zu welchem Zeitpunkt einem Graviditäts-Laktationszyklus...
In this paper, the plasmon field enhanced light-induced changes are investigated in amorphous Ge24Se76 layer incorporating Au nanoparticles. The presence of gold nanoobjects chalcogenide/gold heterostructure influences optical and structural properties, as well volume material. It also enhances Raman signal structure through surface enhancement, which allows clearer better investigation glass understanding mechanisms stimulated transformations. addition, it recording grating pattern into layer.
A double-blind, prospective, randomized, placebo-controlled clinical trial was carried out to test the acute and long-term hemodynamical beneficial cognitive effects of vasoactive agent vinpocetine on patients suffering from multiple cerebral infarcts by means functional transcranial Doppler examinations neuropsychological tests. Twenty-six (17 men, 9 women) with infarctions, aged between 50 83 years (mean age+/-SD=63.4+/-9.39 years) were examined, 14 whom received 12 placebo. The included...
Zusammenfassung Die (8 ‐14 C) markierten Purinbasen Adenin und Guanin sowie die (2 Pyrimidinbasen Cytosin, Uracil Thymin wurden entweder intravenös oder oral an Ratten verabreicht. Applikation von (U Nukleinsäuren erfolgte ausschließlich oral. Nach einem Versuchszeitraum 24 Stunden wurde Verteilung der 14 C‐Aktivität auf möglichen Ausscheidungswege Atemluft, Harn Kot analysiert. Der Verlauf CO 2 ‐Aktivitätsausscheidung mit Hilfe eines Methandurchflußzählers gemessen. i. v. Injektion renale...
Different methods are used to assess the vasodilator ability of cerebral blood vessels; however, exact mechanism vasodilation, induced by different stimuli, is not entirely known. Our aim was investigate whether potent agent, acetazolamide (AZ), inhibits neurovascular coupling, which also requires vasodilation. Therefore, visually evoked flow parameters were examined transcranial Doppler in ten healthy subjects before and after AZ administration. Pulsatility index peak systolic velocity...
The temperature sensitive leucyl-tRNA synthetase mutant tsHl and two revertants have been compared to the parental Chinese hamster ovary cells with respect effects of amino acid concentrations in medium on growth. Elevating leucine concentration 30- or 100-fold allowed grow exponentially at 38.5 degrees C, normally nonpermissive temperature. Partial that had recovered some enzyme activity required smaller supplements for Measurements pools indicated they respond directly extracellular may...
Annual sweet fennel (Foeniculum vulgare var. dulce Mill.), raised by direct field seeding, was evaluated for its horticultural performance and oil quality over three consecutive growing seasons. Plant vigor growth under irrigation fertilizer treatments were rated only as medium. At harvest the majority of umbels green, first killing frost at least 50% plants still in bloom. Oil yields herb fruit 1.22 1.50%, respectively. quality, reflected major minor constituents, determined combined TL-...