- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Bacterial biofilms and quorum sensing
- Pharmacological Effects of Natural Compounds
- Nanoparticles: synthesis and applications
- Moringa oleifera research and applications
- Silk-based biomaterials and applications
- Dental Anxiety and Anesthesia Techniques
- Dental Trauma and Treatments
- Pelvic and Acetabular Injuries
- Wound Healing and Treatments
- Electrochemical sensors and biosensors
- Inflammatory Bowel Disease
- Alkaloids: synthesis and pharmacology
- Orthopedic Infections and Treatments
- Dental Radiography and Imaging
- Pain Mechanisms and Treatments
- Metal Extraction and Bioleaching
- Advanced Nanomaterials in Catalysis
- Otolaryngology and Infectious Diseases
- Nanoplatforms for cancer theranostics
Wuhan University
2016-2024
State Council of the People's Republic of China
2020
Nanjing Drum Tower Hospital
2016
Wuxi No.2 People's Hospital
2015
Dehydrocorydaline (DHC) is an alkaloidal component isolated from Rhizoma corydalis. Previous studies have shown that DHC has anti-inflammatory and anti-tumor effects it can protect the cardiovascular system. However, there are few of antinociceptive in vivo. This study explored possible mechanisms mice using two inflammatory pain models: acetic acid-induced writhing test formalin paw test. The intraperitoneal administration (3.6, 6 or 10 mg/kg) showed a dose-dependent effect significantly...
Ag+ and Zn2+ have already been used in combinations to obtain both enhanced antibacterial effect low cytotoxicity. Despite this, it is still unclear how the co-works with synergistic activity. The main purposes of this study were investigate co-work pattern optimum ratio between their activity against E. faecalis, possible mechanisms behind synergy primary application Ag+-Zn2+ faecalis biofilm on dentin. A serial atomic combination ratios tested planktonic biofilm-resident dentin, efficiency...
In infected periapical tissues, Enterococcus faecalis is one of the most common dominant bacteria. Chlorhexidine has been proved to show strong antibacterial ability against E. but ineffective in promoting mineralization for tissues around root apex. Mesoporous calcium-silicate nanoparticles are newly synthesized biomaterials with excellent promote and carry-release bioactive molecules a controlled manner. this study, mesoporous were functionalized chlorhexidine their releasing profile,...
The infection in burn wounds covered by biologic dressings leads to wound deepening and chronic wounds. introduction of silver nanoparticles (AgNPs) into is a beneficial method prevent simultaneously prom
Maqui berry (Aristotelia chilensis) is an edible berry. The study aimed to explore the therapeutic effect of maqui on inflammatory bowel disease. water extract was separated by multiple solvents extraction. chemical bases, antioxidant and anti-inflammatory properties different fractions were then compared. Dextran sodium sulfate (DSS)-induced ulcerative colitis mice used for pharmacological activity test in vivo. Experimental results showed that ethyl acetate fraction (MWE) rich phenols...
Ca–Si mesoporous nanoparticles with the optimal Ag–Zn ratio showed better color, excellent antibacterial activity, good biocompatibility, and could infiltrate into dentinal tubules.
Enterococcus faecalis (E. faecalis) is one of the dominant bacteria for refractory infections teeth. Silver ions (Ag+) have been proved to be a strong bactericide but with high cytotoxicity and discoloration property. Simvastatin an agent used dyslipidemia treatment has anti-inflammatory In this study, Ag+ simvastatin were first time in combination, poly (lactide-co-glycolide) (PLGA) submicron particles carrying both (AgS-PLGA) fabricated further investigations. Results confirmed enhanced...
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