A5007325276- COVID-19 Impact on Reproduction
- Antioxidant Activity and Oxidative Stress
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Hepatitis B Virus Studies
- Vaccine Coverage and Hesitancy
- Heme Oxygenase-1 and Carbon Monoxide
- Chemotherapy-induced organ toxicity mitigation
- Retinoids in leukemia and cellular processes
- Inflammasome and immune disorders
- Botanical Research and Applications
- Drug-Induced Hepatotoxicity and Protection
- Long-Term Effects of COVID-19
- Ovarian function and disorders
- Coenzyme Q10 studies and effects
- Ferroptosis and cancer prognosis
- Natural Antidiabetic Agents Studies
- Anesthesia and Neurotoxicity Research
- Liver physiology and pathology
- Phytochemicals and Antioxidant Activities
- Drug Transport and Resistance Mechanisms
Atatürk University
2020-2023
Gülhane Askerî Tıp Akademisi
2004
Paracetamol is one of the drugs that cause hepatic damage. Fisetin has wide pharmacological effects such as anticancer, antiinflammatory and antioxidant. We aimed to evaluate possible protective effect fisetin on paracetamol-induced hepatotoxicity. was administered at 25 50 mg/kg doses. orally a dose 2 g/kg for induce hepatotoxicity 1 h after NAC treatments. The rats were sacrificed 24h administration. Tumor necrosis factor-alpha (TNF-α), NFκB CYP2E1 mRNA levels Superoxide dismutase (SOD)...
The aim of this study was to investigate the effects red dragon fruit (Hylocereus polyrhizus) extract (DFE) on stomach in ulcer model induced by indomethacin rats. Effects DFE were evaluated indomethacin-induced gastric damage Sprague–Dawley Experimental model: all rats fasted for 24 h. At end period, administered ulcer-induced groups. One hour after application, a dose 25 mg/kg applied oral gavage groups except HEALTHY and DFE1000 Six hours administration, euthanized with high-dose...
We thought that astaxanthin (ASX) might be a protective agent in oxidative stress damage develops against ischemia and reperfusion injury the rat ovary.The experimental groups consisted of healthy, I (Ischemia), I+ASX50, I+ASX100, I/R (Ischemia/Reperfusion), I/R+ ASX50, ASX100. Vascular clamps were applied to ovaries for 3 hr induce ischemia. For groups, opened blood flow was restored hr. At end experiment, biochemical, histopathological, immunohistochemical analyses made from tissue samples...
The aim of this study was to investigate the effect Astaxanthin (ASX) on ovaries in letrozole-induced polycystic ovary syndrome (PCOS) model female rats by histopathological, immunohistochemical and biochemical techniques.Seventy two Sprague-Dawley with an average weight 200-250 gr 10-12 weeks old were randomly divided into 9 groups. PCOS applied all groups except healthy group. In study, low (10 mg / kg) moderate (20 high (40 doses ASX given experimental animals PCOS-induced for 7 days. At...
Introduction and aim: Vaccine hesitancy vaccine refusal are two of the most important health threats, frequency which has increased in recent years. The confusion caused by both imbalances access to information pollution Covid-19 pandemic reinforced this hesitation. In study, level university students factors affecting it were investigated. Methods: descriptive cross-sectional between December 2021 March 2022 included. sociodemographic characteristics participants recorded Hesitancy...
Abstract Background: This prospective cross-sectional study, aimed to evaluate lymphocyte DNA damage in COVID-19 patients. In this cohort 50 COVID-19- positive patients attending Erzurum City Hospital Internal Medicine Outpatient Clinic and 42 control group were included. Methods: damages detected living cells by isolation using the comet assay method. tail/head (olive) moments evaluated compared. White blood cell (WBC), red (RBC), hemoglobin (HGB), neutrophil (NEU), (LYM), eosinophil (EO),...
This prospective cross-sectional study, aimed to evaluate lymphocyte DNA damage in Coronavirus disease (COVID-19) patients. In this 50 COVID-19 positive patients attending Erzurum City Hospital Internal Medicine Outpatient Clinic and 42 control group were included. damages detected living cells by isolation COVID-19- using the comet assay method. tail/head (olive) moments evaluated compared. White blood cell (WBC), red (RBC), hemoglobin (HGB), neutrophil (NEU), (LYM), eosinophil (EO),...