A5100443176- Prostate Cancer Treatment and Research
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Research Studies
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Cancer survivorship and care
- Brain Metastases and Treatment
- Cancer Genomics and Diagnostics
- Cancer Cells and Metastasis
- Cardiac, Anesthesia and Surgical Outcomes
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genomics and Chromatin Dynamics
- Microtubule and mitosis dynamics
- Cancer, Lipids, and Metabolism
- Clinical practice guidelines implementation
- Lung Cancer Treatments and Mutations
- Genetic factors in colorectal cancer
Tsinghua University
2025
Lishui Central Hospital
2023
Second People’s Hospital of Yibin
2023
Wenzhou Medical University
2023
Sun Yat-sen Memorial Hospital
2017
Sun Yat-sen University
2017
University of Southern California
2008
The androgen receptor (AR) is a steroid-activated transcription factor that binds at specific DNA locations and plays key role in the etiology of prostate cancer. While numerous studies have identified clear connection between AR binding expression target genes for limited number loci, high-throughput elucidation these sites allows deeper understanding complexities this process.We mapped 189 occupied regions (ARORs) 1,388 histone H3 acetylation (AcH3) loci to 3% continuous stretch human...
Tumor heterogeneity and clonal evolution are related to the treatment resistance disease progression in metastatic breast cancer (MBC). However, process of their relationship prognosis remain unclear. This study aimed elucidate MBC through circulating tumor DNA (ctDNA) analysis develop a novel indicator for predicting efficacy prognosis. multicenter retrospective enrolled patients who underwent next-generation sequencing between April 2016 October 2022. The tumors was inferred using PyClone...
DEP domain‑containing protein 1B (DEPDC1B) has been reported to serve important functions in breast cancer and non‑small cell lung cancer. However, its involvement the development of prostate (PCa) remains unclear. Therefore, present study aimed investigate expression clinical significance DEPDC1B tumor tissues from patients diagnosed with PCa. A total 80 tissue samples were collected following prostatectomy generate a microarray for immunohistochemical analysis expression. High throughput...
Background Lung cancer is the second most common form of malignant tumor and has highest mortality rate worldwide. Among its subtypes, lung adenocarcinoma prevalent. Leptomeningeal metastasis (LM) rare characterized by a dismal prognosis, with overall survival periods typically spanning 4 to 6 weeks without treatment. However, in specific cases, can be extended months appropriate therapy. The recent approval third-generation tyrosine kinase inhibitors (TKIs), such as osimertinib,...
Introduction Symptom monitoring and alerting based on patient-reported outcomes have proven valuable in a postoperative setting. However, the parameters of implemented patient-centred symptom management system for patients with prostate cancer (PC) remain unclear. This study aims to develop perioperative scale (PSS) monitor symptoms, determine appropriate timing assessment establish intervention criteria physicians. Methods analysis We will prospectively recruit 387 undergoing PC surgery 3...
Rationale: Very-high-risk prostate cancer (PCa) is associated with poor prognosis. Radical prostatectomy (RP) an option for selected high-risk PCa cases, especially in younger, healthier patients. However, a high Gleason score and T stage can increase the risk of RP. Neoadjuvant therapy has been reported high- or very-high-risk PCa, but its clinical use remains controversial. Diagnoses patient concerns: A 53-year-old male diagnosed was referred to our hospital. The patient’s 4 + 5, T4N0M0,...