- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Nitric Oxide and Endothelin Effects
- Luminescence and Fluorescent Materials
- Lanthanide and Transition Metal Complexes
- Radioactive element chemistry and processing
- Electrochemical Analysis and Applications
- Folate and B Vitamins Research
- Trace Elements in Health
- Electrochemical sensors and biosensors
- Eicosanoids and Hypertension Pharmacology
- MicroRNA in disease regulation
- Nanoplatforms for cancer theranostics
- RNA modifications and cancer
- Analytical Chemistry and Sensors
- Supramolecular Chemistry and Complexes
- Advanced Nanomaterials in Catalysis
- Mast cells and histamine
- Drug Transport and Resistance Mechanisms
- Covalent Organic Framework Applications
- Arsenic contamination and mitigation
- Adenosine and Purinergic Signaling
- Amino Acid Enzymes and Metabolism
- Antibiotics Pharmacokinetics and Efficacy
- Ferroptosis and cancer prognosis
Collaborative Innovation Center of Advanced Microstructures
2022-2025
Nanjing University
2022-2025
Hubei University
2017-2020
Taizhou University
2018-2019
Hainan Medical University
2019
Small-molecule biothiols, including cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), participate in various pathological physiological processes. It is still a challenge to simultaneously distinguish Cys Hcy because of their similar structures reactivities, as well the interference from high intramolecular concentration GSH. Herein, novel fluorescent probe, CySI, based on cyanine thioester was developed differentiate through single-wavelength excitation two distinctly separated...
Adenosine triphosphate (ATP), as an important intracellular energy currency produced in mitochondria, is closely related to various diseases living organisms. Currently, the biological application of AIE fluorophore a fluorescent probe for ATP detection mitochondria rarely reported. Herein, D−π–A and D–A structure-based tetraphenylethylene (TPE) fluorophores were employed synthesize six different probes (P1–P6), phenylboronic acid groups dual positive charge sites could interact with vicinal...
Rheumatoid arthritis (RA), a common chronic inflammatory illness, is still incurable, reducing the sufferers' quality of life significantly. Adenosine 5′-triphosphate (ATP) and hypochlorous acid (HOCl) are key indicators in RA, but their precise mechanisms RA pathophysiology unknown. As result, order to detect ATP HOCl simultaneously, we created two new dual-channel/localization single-molecule fluorescence probes, RhTNMB RhFNMB. Furthermore, RhFNMB outperformed terms detection performance....
Mitochondria are important subcellular organelles involved in many cellular activities. Therefore, it is very to monitor the concentration of various substances mitochondria. In this work, we constructed a dual-response mitochondria-targeted fluorescent probe HBTN for detection viscosity and HOCl vitro vivo. not only has long emission wavelength with an peak 680 nm, but also large Stokes shift 278 nm. The fluorescence intensity at nm good linear relationship solution viscosity, which can be...
The limited availability of uranium (U) resources poses significant challenges to the advancement nuclear energy. Recycling from spent fuel is critical, but coexistence lanthanides (Ln) complicates extraction process significantly. Here, we present an N/O ligand, (E)-N′-(pyridin-2-ylmethylene) picolinohydrazide (PYPH), designed for selective recovery U(VI) over Ln(III/IV) in acidic environments. 3,6-Bis(2-pyridinyl)-1,2,4,5-tetrazine (BPTZ) and N,N-dimethylformamide (DMF), when subjected...