A5027021610- Prenatal Substance Exposure Effects
- Maternal Mental Health During Pregnancy and Postpartum
- Neuroscience of respiration and sleep
- Breastfeeding Practices and Influences
- Birth, Development, and Health
- Neonatal Health and Biochemistry
- Infant Development and Preterm Care
- Opioid Use Disorder Treatment
- Homelessness and Social Issues
- Substance Abuse Treatment and Outcomes
- Sleep and Wakefulness Research
- Bone health and osteoporosis research
- Sleep and related disorders
- Cannabis and Cannabinoid Research
- Gut microbiota and health
- Health and Medical Education
- Child Abuse and Trauma
- Pregnancy-related medical research
- Mindfulness and Compassion Interventions
- Intimate Partner and Family Violence
- Neonatal and fetal brain pathology
- Infant Nutrition and Health
- Diet and metabolism studies
- Cognitive Abilities and Testing
- Childhood Cancer Survivors' Quality of Life
Johns Hopkins Medicine
2014-2024
Johns Hopkins University
2014-2024
National Council on Aging
2020
Families USA
2020
Greater Lawrence Family Health Center
2019
Johns Hopkins Bayview Medical Center
1997-2015
Committee on Publication Ethics
2015
Parenting Research Centre
1999
National Institute on Drug Abuse
1994
Universidad de Antioquia
1990
The infant exposed to opioids in utero frequently presents a challenge the neonatal care provider assessment and treatment of symptoms Neonatal Abstinence Syndrome (NAS) after birth. This review is intended provide healthcare professional with brief current evidence practical guidelines for optimal evaluation pharmacologic management opioid-exposed newborn.
Opioid dependent pregnant and postpartum women their infants are a complex vulnerable population requiring individualized, comprehensive, multidisciplinary treatment. Though methadone maintenance in the setting of comprehensive service provision during pregnancy significantly improves outcomes for opioid women, its use has implications infant, most notably neonatal abstinence syndrome. Neonatal syndrome is comprised physiologic signs behaviors that indicate dysfunctional regulation central...
In a sample of methadone-maintained breastfeeding women and matched group formula-feeding women, this study evaluated concentrations methadone in breast milk among maternal infant plasma both groups.Eight (dose: 50-105 mg/day), lactating provided blood specimens on days 1, 2, 3, 4, 14, 30 after delivery, at the times trough peak levels. Paired foremilk hindmilk were obtained each sampling time. Eight subjects samples same days. Infant for groups day 14. Urine toxicological screening between...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning /...
Neonatal intensive care unit (NICU) and drug treatment costs were compared in two groups of pregnant abusing women: 100 admissions to a multidisciplinary program active at the time delivery 46 controls not entering treatment. Clinical measures included urine toxicology delivery, infant birthweight. Apgar scores need for duration NICU services. Cost costs. Treatment patients showed better clinical outcome with less use higher estimated gestational age, birthweight scores. Infants also likely...
Objective. Though methadone pharmacotherapy is the treatment of choice for opiate-dependence during pregnancy in USA, most methadone-exposed neonates develop neonatal abstinence syndrome (NAS). NAS expression widely variable among and only a subset requires pharmacotherapy. This study explores potential predictors severity, including aspects maternal substance use maintenance histories, concomitant exposure to other licit substances, individual differences intrinsic or infant factors that...
Abstract Background Caribbean Latino adults are at high risk for osteoporosis yet remain underrepresented in bone research. This increased is attributed to genetics, diet, and lifestyle known drive inflammation microbial dysbiosis. Objective The primary objective of this study was determine whether consuming 5 oz yogurt daily 8wks improves turnover markers (BTMs) among > 50 years; secondarily the impact on gut microbiota intestinal integrity inflammation. Methods Following a 4wk baseline...
This study evaluates concentrations of methadone in breast milk and plasma among a sample methadone-maintained women the immediate perinatal period. Twelve methadone-maintained, lactating provided blood specimens 1, 2, 3, 4 days after delivery. Specimens were collected at time trough (just before dose) peak (3 hours dosing) maternal levels. Paired foremilk (prefeed) hindmilk (postfeed) obtained each sampling time. Although there was significant increase concentration over for postfeed time,...
Objective. Daily methadone maintenance is the standard of care for opiate dependency during pregnancy. Previous research has indicated that single-dose maternal administration significantly suppresses fetal neurobehaviours. The purpose this study was to determine if split-dosing would have less impact on neurobehaviour than administration.Methods. Forty methadone-maintained women were evaluated at peak and trough levels single- schedules. Monitoring sessions occurred 36- 37-weeks gestation...
This study examined the neurobehavioral functioning of neonates prenatally exposed to methadone (n = 11) or buprenorphine 10), who underwent Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) examinations on days 3, 5, 7, 10, and 14 post-delivery. Linear mixed model analyses revealed that NNNS scores arousal excitability showed significant differences between medications over time. Compared did not require medication treat neonatal abstinence syndrome (NAS), receiving...
Background: In addition to the well-known benefits of human milk and breastfeeding for mother infant, may mitigate neonatal abstinence syndrome severity in prenatally opioid-exposed infants. However, lack conclusive data regarding extent presence buprenorphine active metabolites makes recommendation buprenorphine-maintained women difficult many providers. Objective: This study seeks determine concentrations its (norbuprenorphine, buprenorphine-glucuronide, norbuprenorphine-glucuronide) milk,...