A5067465067- Synthesis and biological activity
- Free Radicals and Antioxidants
- Metal complexes synthesis and properties
- COVID-19 Clinical Research Studies
- Vitamin D Research Studies
- Computational Drug Discovery Methods
- Photochemistry and Electron Transfer Studies
- Iron Metabolism and Disorders
- Bioactive Compounds and Antitumor Agents
- Synthesis and Characterization of Heterocyclic Compounds
- Tuberculosis Research and Epidemiology
- Thyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Renal function and acid-base balance
- Bone health and osteoporosis research
- Vitamin C and Antioxidants Research
- Pharmacological Effects and Toxicity Studies
- Human Health and Disease
- Reproductive System and Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Ferrocene Chemistry and Applications
- Thyroid Cancer Diagnosis and Treatment
- Hydrogen's biological and therapeutic effects
- Travel-related health issues
University of Kragujevac
2015-2024
Clinical Centre of Kragujevac
2011-2024
Institute for Cardiovascular Diseases of Vojvodina
2000
Disruption of homeostasis can increase the amount free radicals formed during metabolic processes. This phenomenon known as oxidative stress have numerous negative outcomes. The role dietary antioxidants is to help prevention stress. We investigated radical scavenging capacity six structurally similar anthraquinones (alizarin, purpurin, chrysophanol, emodin, aloe-emodin and 1,3,8-trihydroxyanthraquinone) for inactivating a set ten hydroxy peroxy radicals. antioxidant was estimated by...
Bearing in mind that coronavirus disease (COVID-19) is associated with a wide range of laboratory abnormalities, the aim this study was to examine importance determining parameters oxidative stress and antioxidant protection as well markers inflammation hemostasis hospitalized patients COVID-19. The population included 105 severe COVID-19 65 healthy control subjects. activity enzymes system were determined from obtained samples using spectrophotometric methods. Standard methods performed for...
Abstract Measurement of serum thyroglobulin (Tg) is a highly specific test in the management patients with differentiated thyroid cancer (DTC) after surgical treatment. The aim our study was to evaluate and compare Tg levels these found by radioimmunoassay (RIA) immunoradiometric assay (IRMA) assess influence antibodies (TgAbs) on values obtained for concentration. Both TgAb were determined postoperatively 71 DTC using RIA Tg‐PEG (INEP) IRMA (CIS) Tg, together circulating endogenous...
Calculations based on the density functional theory, with B3LYP and 6-311++G(d,p) basis set, were performed aim of confirming molecular structure spectroscopic characteristics kaempferol, a naturally occurring flavonoid molecule. The electronic kaempferol was examined using NBO analysis. assigning experimentally obtained IR Raman spectra after best-fit-based comparison theoretical spectra. 13C 1H NMR experimental related to theoretically values chemical shifts determined by GIAO method....
Cardiovascular diseases (CVDs) are a leading cause of death. If not treated in timely manner, cardiovascular can plethora major life complications that include disability and loss the ability to work. Globally, acute myocardial infarction (AMI) is responsible for about 3 million deaths year. The development strategies prevention, but also early detection risks, great importance. fractional flow reserve (FFR) measurement used an assessment severity coronary artery stenosis. goal this research...
As apoptosis and genome instability in children with autoimmune diseases (AIDs) are insufficiently investigated, we aimed to analyse them peripheral blood lymphocytes (PBLs) of adolescents Hashimoto's thyroiditis (HT), Graves' disease (GD) type 1 diabetes mellitus (T1DM), including possible factors that could affect their occurrence. The study population included 24 patients 19 healthy controls. Apoptotic cells were detected using an Annexin V-FITC/7-AAD kit. Genome was measured as...
This research aimed to investigate factors associated with vitamin D deficiency and provide data about its prevalence in patients suffering from different psychiatric illnesses. The study had a cross-sectional design it included 220 of both genders, aged 19-81 y, wide range mental disorders (F00-F89), treated routine ambulatory hospital practice. researchers collected three sources: medical records, questionnaire biochemical analysis patients' serum samples (concentration measured as...
There are a large number of commercial diagnostic assays for measuring thyroglobulin (Tg) concentration in human serum. The assay principle, as well the potential presence antithyroglobulin autoantibody (TgAb) patient's serum, could influence measured amount Tg. Our objective was to determine Tg by radioimmunoassay and immunoradiometric assay, compare values obtained investigate TgAbs on those results. Analysis serum specimens (n = 58) showed close correlation between investigated assays,...
The aim of this research is the synthesis and characterization coumarin-palladium complex investigation cytotoxicity both ligand complex.
Objective Serum parameters of calcium homeostasis were measured based on previously published evidence linking osteoporotic fractures and/or bone/mineral loss with antipsychotics. Methods Prospective, four-week, time-series trial was conducted and study population consisted patients both genders, aged 35-85 years, admitted within the routine practice, acute psychotic symptoms, to whom an antipsychotic drug either introduced or substituted. Serial measurements serum calcium, phosphorous,...
Background/Aim. The use of cisplatin as a chemotherapeutic opened the door to new metal-based drug research. New complexes containing metals such platinum, palladium, ruthenium and gold have recently been analyzed potential antitumor agents. aim study was investigate cytotoxicity Au(III) with pincer-type ligands against cervical carcinoma cells (HeLa), breast cancer (MDA-MB-231 4T1) colon (HCT116 CT26), well examine type mechanism cell death that these induced in cells. Methods. investigated...
Introduction. Pneumonia is the most frequent nosocomial infection in intensive care units. The reported frequency varies with definition, type of hospital or units and population patients. incidence ranges from 6.8-27%. Objective. objective this study was to determine frequency, risk factors mortality pneumonia Methods. We analyzed retrospectively prospectively collected data 180 patients central nervous system infections who needed stay unit for more than 48 hours. This conducted 2003 2009...
Background/Aim. The main cause for development of endometrial hyperplasia is unopposed effect estrogen on cells. aim our study was to investigate and compare cytotoxic apoptotic effects mifepristone human stromal cell line the first time. Both percentage cells were determined after 24 h treatment with different doses mifepristone. Methods. evaluated by viability assay while using flow cytometry. Determination confirmed immunofluorescence method determining expression localization active Bax...
Abstract Microinflammation is a non-traditional risk factor for the development of cardiovascular diseases in patients on hemodialysis. It occurs 30-50% these patients, and its main causes are: uremic toxins, oxidative stress, metabolic acidosis, vitamin D deficiency, overhydration, altered intestinal microbiome, impaired epithelial barrier integrity, increased translocation endotoxin from lumen into systemic circulation, occult infection vascular approach hemodialysis, periodontal disease,...