A5026734992- Cancer-related molecular mechanisms research
- Microtubule and mitosis dynamics
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Kruppel-like factors research
- RNA Research and Splicing
- Vascular Tumors and Angiosarcomas
- Cancer-related Molecular Pathways
- Mycobacterium research and diagnosis
- Craniofacial Disorders and Treatments
- Genomics and Chromatin Dynamics
- Ubiquitin and proteasome pathways
- Cancer, Lipids, and Metabolism
- Cholesterol and Lipid Metabolism
- Computational Drug Discovery Methods
- Head and Neck Surgical Oncology
- Melanoma and MAPK Pathways
- Ferroptosis and cancer prognosis
- Angiogenesis and VEGF in Cancer
- Liver Disease Diagnosis and Treatment
- Molecular Biology Techniques and Applications
- Cleft Lip and Palate Research
- Enzyme function and inhibition
- Esophageal Cancer Research and Treatment
- Cancer, Hypoxia, and Metabolism
Guangzhou University of Chinese Medicine
2022-2023
Affiliated Hospital of Nantong University
2021
Nantong University
2021
The Fourth People's Hospital
2019
Jiangsu University
2017-2018
Affiliated Hospital of Jiangsu University
2017-2018
Jangan University
2014
Southern Illinois University School of Medicine
2006
Zhejiang University
2003
Background: Hepatocellular carcinoma (HCC) is associated with chronic inflammation caused by different factors; especially, the interaction of inflammatory pathways and bile acids (BAs) can affect hepatocyte proliferation, death, regeneration, but whether BAs promote HCC progression through mechanisms still unclear. Methods results: By examining cancer tumor-adjacent tissue BA levels genes homeostasis in 37 patients, we found that total (TBAs) were decreased 36% varying degrees changes...
A novel breast cancer cell line (RAO-3) was established by transduction of the Q61L mutant RAS into human mammary epithelial cells that were immortalized with catalytic subunit telomerase (hTERT). The displayed anchorage-independent growth and proliferation, formed spindle carcinoma when injected nude mice. Chromosome locus 1q22-23 partially duplicated inverted on one 3 chromosomes present in line. We report here mutations chromosome have resulted loss RAB25 expression Transduction arrests...
Acidification is recognized as the predominant characteristic of tumor microenvironment (TME) and contributes to progression. However, mechanism extracellular acidic TME directly influences intercellular pathologic responses remains unclear. Meanwhile, mainly ascribed aberrant metabolism lipids glucose, but whether how acidity affects metabolic reprogramming, especially for lipid metabolism, still unknown. We found that was significantly accumulated in liver cancer cells when exposed TME....
To elucidate the function of lncRNA RMRP in hypoxia-induced acute myocardial infarction (AMI) vitro and explore its underlying mechanism.Hypoxic injury was confirmed by measurement cell viability, LDH release, migration, invasion, apoptosis H9c2 cells. The interactions between miR-214-5p as well p53 were also investigated.Hypoxia treatment significantly induced damage cells, accompanied with up-regulation expressions. Transfection siRNA remarkably attenuated enhancing migration reducing...
Abstract The critical roles of E3 ubiquitin ligase RNF168 have been widely revealed in various tumors, however, its lung cancer progression are still confusing. Here, we found that expression is positively correlated with the overall survival, first‐progression and postprogression survival adenocarcinoma, but not these survivals squamous cell carcinoma lung. Furthermore, it was shown mRNA lowly expressed adenocarcinoma tissues, highly Functional experiments indicated overexpression...