A5062835039- Natural Compound Pharmacology Studies
- Bioactive Compounds and Antitumor Agents
- Carbohydrate Chemistry and Synthesis
- HIV Research and Treatment
- Glycosylation and Glycoproteins Research
- Chronic Lymphocytic Leukemia Research
- Molecular spectroscopy and chirality
Institut Agro Rennes-Angers
2017-2020
Université d'Angers
2017-2018
Center for Research in Transplantation and Translational Immunology
2017
Inserm
2017
Centre d'Investigation Clinique de Nantes
2017
Modulation of major histocompatibility complex (MHC) expression using drugs has been proposed to control immunity. Phytochemical investigations on Garcinia species have allowed the isolation bioactive compounds such as polycyclic polyprenylated acylphloroglucinols (PPAPs). PPAPs guttiferone J (1), display anti-inflammatory and immunoregulatory activities while garcinol (4) is a histone acetyltransferases (HAT) p300 inhibitor. This study reports isolation, identification biological...