A5101830854- Luminescence and Fluorescent Materials
- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Supercapacitor Materials and Fabrication
- Advancements in Battery Materials
- Advanced Polymer Synthesis and Characterization
- Supramolecular Chemistry and Complexes
- Covalent Organic Framework Applications
- Supramolecular Self-Assembly in Materials
- Advanced battery technologies research
- Protein Interaction Studies and Fluorescence Analysis
- Fluorine in Organic Chemistry
- Ocular Surface and Contact Lens
- Lipid Membrane Structure and Behavior
- Biopolymer Synthesis and Applications
- Molecular Biology Techniques and Applications
- Click Chemistry and Applications
- Membrane Separation and Gas Transport
- Amino Acid Enzymes and Metabolism
- Electrospun Nanofibers in Biomedical Applications
- Liquid Crystal Research Advancements
- Block Copolymer Self-Assembly
- Bee Products Chemical Analysis
- Chemical Synthesis and Analysis
- Advanced Battery Materials and Technologies
Zhejiang Sci-Tech University
2017-2021
Hangzhou Xixi hospital
2017
Herein, a dual-responsive insulin delivery device by integrating glucose- and H2O2-responsive polymeric vesicles (PVs) with transcutaneous microneedles (MNs) has been designed. This novel microneedle achieves goal of fast response, excellent biocompatibility, painless administration. The PVs are self-assembled from triblock copolymer including poly(ethylene glycol), poly(phenylboronic acid) (glucose-sensitive block), acid pinacol ester) (H2O2-sensitive block). After loading glucose oxidase...
A glucose-mediated insulin delivery system would be highly satisfactory for diabetes diagnosis dependent on the concentration of blood glucose in body. Herein, a novel microneedle (MN) device integrated with insulin-loaded and H2O2-responsive mesoporous silica nanoparticles (MSNs) was designed to achieve fast painless administration. The MSNs were obtained by modification 4-(imidazoyl carbamate)phenylboronic acid pinacol ester (ICBE) following host-guest complexation between ICBE...
Near-infrared light triggered and separable microneedles (MNs) were fabricated by a unique molding method. The photothermal conversion agent (Prussian blue nanoparticles, PB NPs) hypoglycemic drug (metformin) embedded into the polycaprolactone (PCL) MNs arrowheads. These arrowheads capped on dissolving polyvinyl alcohol/polyvinyl pyrrolidone (PVA/PVP) solid supporting substrate. as-fabricated exhibited excellent properties under near-infrared (NIR) irradiation, causing to melt due of NPs....
Dual photo- and pH-responsive polymeric vesicles are constructed from a host–guest complex between water-soluble pillar[6]arene an azobenzene ended functionalized poly(ε-caprolactone). Reversible morphological transitions solid aggregates achieved upon repeated UV stimulus pH stimulus. Moreover, the present excellent cytocompatibility toward HepG2 cells can be further applied for controlled release of hydrophilic model drug, DOX•HCl. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A:...
Abstract Two ionic block copolymers with different lengths of hydrophilic segments, polystyrene‐ b ‐poly(quaternized 4‐vinylpyridine)/ethyl bromide, are prepared by sequential reactions. They originally self‐assembled into so‐called “large compound micelles” in aqueous solution. After ion exchange Iˉ, SCN,ˉ and PF 6 ˉ for Brˉ, morphological transitions controlled a competition solvation size effects the newly introduced counterions. The effect is dominated relatively short corona‐forming...
Herein, for rate-tunable controlled release, pH and redox dual responsive polymeric vesicles were constructed based on host-guest interaction between a water soluble pillar[5]arene (WP5) paraquat-containing block copolymer (BCP) in water. The yielding can be further applied the release of hydrophilic model drug, doxorubicin hydrochloride (DOX). drug rate is regulated depending type single stimulus or combination two stimuli. Meanwhile, DOX-loaded present anticancer activity vitro comparable...
The identification of ancient wool is great significance in archaeology; however, conventional methods are unwieldy or even ineffective when testing contaminated severely degraded samples. Therefore, it highly desirable to develop an ultrasensitive detection method for wool. In this study, electrochemical immunosensor proposed and developed detect wool, where graphene oxide (GO), aldehyde-functionalized ionic liquid (AFIL) composites gold nanoparticles (AuNPs) synthesized as efficient signal...
During the development of high-capacity, ultra-stable battery electrode materials, performance, and safety issues are proved to be related properties electrolyte used. The employment additives is improve properties. Representative commercial two-electrode LiCoO 2 //graphite pouch cells used study represented by fluoroethylene carbonate (FEC) electrochemical stability full cell. reveals that 1.5% FEC additive has best in voltage range 3.0-4.2 V.
Ad ynamic library including an Fe II 4 L 6 irregular structure and three 2 3 stereoisomers was formed by subcomponent self-assembly.Glucose amplifies the formation of (P)-Fe helicate, which in turn b-D-glucose at expense a-D-anomer.Both host guest libraries are thus geared together into as ingle system during equilibration.Wacker-type reaction cyclic alkenes, propargylic acetates nucleophilic heteroarenes arenes, indoles, pyrroles, activated thiophenes, furans anilines, proceeds to give...