A5001307762- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Heart Rate Variability and Autonomic Control
- Neuroscience and Music Perception
- Traumatic Brain Injury and Neurovascular Disturbances
- Neural Networks and Applications
- Blind Source Separation Techniques
- Advanced Neuroimaging Techniques and Applications
- Spatial Neglect and Hemispheric Dysfunction
- Multisensory perception and integration
- Hearing Loss and Rehabilitation
- Advanced MRI Techniques and Applications
- Action Observation and Synchronization
- Non-Invasive Vital Sign Monitoring
- Psychosomatic Disorders and Their Treatments
- Microbial Metabolic Engineering and Bioproduction
- Neonatal and fetal brain pathology
- Intensive Care Unit Cognitive Disorders
- Visual perception and processing mechanisms
- Medical Image Segmentation Techniques
- Enzyme Catalysis and Immobilization
Centre d'Imagerie BioMedicale
2007-2025
University of Lausanne
2016-2025
University Hospital of Lausanne
2009-2025
Sapienza University of Rome
2004-2015
University of Modena and Reggio Emilia
2008-2013
University College London
2006-2007
Enrico Fermi Center for Study and Research
2005
Istituto Nazionale per la Fisica della Materia
2002
Abstract Background The production of microbial lipids has attracted considerable interest during the past decade since they can be successfully used to produce biodiesel by catalyzed transesterification with short chain alcohols. Certain yeast species, including several psychrophilic isolates, are oleaginous and accumulate from 20 70% biomass under appropriate cultivation conditions. Among them, Rhodotorula glacialis is a basidiomycetous species capable intracellular lipids. Results DBVPG...
Auditory evoked potentials are informative of intact cortical functions comatose patients. The integrity auditory evaluated using mismatch negativity paradigms has been associated with their chances survival. However, because discrimination is assessed at various delays after coma onset, it still unclear whether this impairment depends on the time recording. We hypothesized that in capabilities indicative progression, rather than state itself and rudimentary remains during acute stages coma....
Abstract Assessing the integrity of neural functions in coma after cardiac arrest remains an open challenge. Prognostication outcome relies mainly on visual expert scoring physiological signals, which is prone to subjectivity and leaves a considerable number patients ‘grey zone’, with uncertain prognosis. Quantitative analysis EEG responses auditory stimuli can provide window into information about patients’ chances awakening. However, standardized stimulation are far from being used...
The ability to discriminate conspecific vocalizations is observed across species and early during development. However, its neurophysiologic mechanism remains controversial, particularly regarding whether it involves specialized processes with dedicated neural machinery. We identified spatiotemporal brain mechanisms for vocalization discrimination in humans by applying electrical neuroimaging analyses auditory evoked potentials (AEPs) response acoustically psychophysically controlled...
The neural response to a violation of sequences identical sounds is typical example the brain's sensitivity auditory regularities. Previous literature interprets this effect as pre-attentive and unconscious processing sensory stimuli. By contrast, global regularities, i.e. based on repeating groups sounds, typically detectable when subjects can consciously perceive them. Here, we challenge notion that detection implies consciousness by testing violations in group 24 patients with post-anoxic...
Most of the available clinical tests for prognosis postanoxic coma are informative poor outcome. Previous work has shown that an improvement in auditory discrimination over first days is predictive awakening. Here, we aimed at evaluating this test on a large cohort patients undergoing therapeutic hypothermia and investigating its added value existing measures.We recorded electroencephalographic responses to stimuli 94 comatose patients, under after rewarming normal temperature. Auditory was...
Abstract We assessed outcome prediction of comatose patients using a deep learning analysis applied to resting EEG on the first and second day after cardiac arrest (CA), its added value clinical prognosis. recorded 62-channel resting-state in CA across three Swiss hospitals during (N=165) (N=100) coma day. Patient was classified as favorable if best Cerebral Performance Category 1-2. A convolutional neural network provided predicted probability for each patient’s recording day’s 19-channel...
An open challenge in consciousness research is understanding how neural functions are altered by pathological loss of consciousness. To maintain consciousness, the brain needs synchronized communication information across regions, and sufficient complexity activity. Coordination activity, typically indexed through measures synchrony, has been shown to decrease when lost reflect clinical state patients with disorders Moreover, lost, activity loses complexity, while levels noise, slope...
Studies with event-related potentials have highlighted deficits in the early phases of orienting to left visual targets right-brain-damaged patients spatial neglect (N+). However, brain responses associated preparatory attention, target novelty and detection a match/mismatch between expected actual (contextual updating), not been explored N+. Here study healthy humans brain-damaged both sexes we demonstrate that frontal activity reflects supramodal mechanisms attentional (Anterior Directing...
Behavioral and brain responses to identical stimuli can vary with experimental task parameters, including the context of stimulus presentation or attention. More surprisingly, computational models suggest that noise-related random fluctuations in would alone be sufficient engender perceptual differences between physically stimuli. In two experiments combining psychophysics EEG healthy humans, we investigated mechanisms whereby are (erroneously) perceived as different (higher vs lower pitch...
Behavioral assessments of consciousness based on overt command following cannot differentiate patients with disorders (DOC) from those who demonstrate a dissociation between intent/awareness and motor capacity: cognitive (CMD). We argue that delineation peri-personal space (PPS) – the multisensory-motor immediately surrounding body may these due to its central role in mediating human-environment interactions, putatively scaffolding minimal form selfhood. In Experiment 1, we determined...
Repetition of environmental sounds, like their visual counterparts, can facilitate behavior and modulate neural responses, exemplifying plasticity in how auditory objects are represented or accessed. It remains controversial whether such repetition priming/suppression involves solely based on acoustic features and/or also access to semantic features. To evaluate contributions physical eliciting repetition-induced plasticity, the present functional magnetic resonance imaging (fMRI) study...