A5086488099- COVID-19 Clinical Research Studies
- Pregnancy and preeclampsia studies
- Dermatological and COVID-19 studies
- Long-Term Effects of COVID-19
- Inflammasome and immune disorders
- Pregnancy and Medication Impact
- Folate and B Vitamins Research
- Bone health and osteoporosis research
- Birth, Development, and Health
- Inflammatory Biomarkers in Disease Prognosis
- Whipple's Disease and Interleukins
- Healthcare Regulation
- Reproductive System and Pregnancy
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer Cells and Metastasis
- Endometriosis Research and Treatment
- Cancer Research and Treatments
- Inflammation biomarkers and pathways
Universidade Federal do Triângulo Mineiro
2016-2024
COVID-19, also known as coronavirus disease 2019, is an infectious viral caused by SARS-CoV-2, a novel coronavirus. Since its emergence, epidemiology has been explored; however, for some regions of the world, COVID-19’s behavior, incidence, and impact remain unclear. In continental nations like Brazil, this lack knowledge results in nonuniform control, prevention, treatment measures, which can be controversial locations. This study aimed to describe epidemiological profile patients with...
Introduction: Preeclampsia is defined by the development of hypertension associated with proteinuria after 20 th week gestation in previously normotensive women.IL17A a potent inducer tissue inflammation and polymorphisms IL17A gene can modulate expression affect functioning Th17 cells, strengthening susceptibility to preeclampsia.Objective: To investigate rs4711998 A> G, rs8193036 C> T rs2275913 G women preeclampsia.Methods: This control case study, composed 263 women, 89 preeclampsia 174...
Objective The present study aims to investigate the association between caspase-8 (CASP8) (rs13416436 and rs2037815) Fas cell surface death receptor (FAS) (rs3740286 rs4064) polymorphisms with endometriosis in Brazilian women. Methods In case-control study, 45 women a diagnosis of 78 normal healthy as control group were included. genotyping was determined by real-time polymerase chain reaction (PCR) Taqman hydrolysis probes (Thermo Fisher Scientific, Darmstadt, Germany). Genotypic allelic...
Background/Objectives: Cytokine storm in severe COVID-19 is responsible for irreversible tissue damage and death. Soluble mediators from the TNF superfamily, their correlation with clinical outcome, use of receptors as a potent predictor outcome were evaluated. Methods: Severe patients had levels soluble superfamily quantified categorized according to (death versus survival). Statistical modeling was performed predict outcomes. Results: have elevated serum superfamily. Regardless sex age,...
Abstract Objectives: to verify the contribution of polymorphisms rs1800469 and rs1800468 TGF-β1 gene risk factors for pre-eclampsia development. Methods: this is a case-control study with 257 women from Uberaba region Minas Gerais were selected, 88 them in group 169 control group. Genotyping was performed by allelic discrimination using real-time PCR technique. The odds ratio 95% confidence interval used evaluate probability studied contributing logistic regression analysis relation among...
Beside the acute respiratory syndrome caused by COVID-19, exacerbated inflammatory process leads to systemic coagulation disorders, cardiovascular renal failure, metabolic changes and other clinical manifestations, increasing mortality of patients with severe forms disease. The development effective vaccines drugs for adequate treatment disease has become a priority scientific medical community. Likewise, discovery possible predictors early identification cases high risk death are constantly...
Pre-eclampsia results in real risk and significant impact on indicators related to maternal child health. The only known treatment is delivery of the fetus placenta. Despite intensive research, causes PE remain be elucidated. It suggested that pre-eclampsia caused by a global inflammatory response damaged Besides inflammation, cytotoxic apoptotic mechanisms are also implicated pathogenesis pre-eclampsia. Considering importance apoptosis genesis, aim this study was determine frequencies...
This study aimed to investigate the role of TGF-β1 gene in SARS-CoV-2 infection. A total 178 individuals diagnosed with Covid-19 participated and, they were divided two groups related outcome (discharge or death). Genotyping rs1800468 and rs1800469 polymorphisms was performed samples, using allelic discrimination technique expression analysis 93 samples by Real Time PCR. There no association between genotypic frequencies analyzed prognosis patients Covid-19. significant difference clinical...