A5016444107- Research on Leishmaniasis Studies
- Organometallic Compounds Synthesis and Characterization
- COVID-19 Clinical Research Studies
- Metal complexes synthesis and properties
- Bone Tissue Engineering Materials
- Malaria Research and Control
- Metal and Thin Film Mechanics
- Titanium Alloys Microstructure and Properties
- Science and Education Research
- Long-Term Effects of COVID-19
- Dermatological and COVID-19 studies
- Congenital Anomalies and Fetal Surgery
- Antimicrobial Peptides and Activities
- Orthopaedic implants and arthroplasty
- Trypanosoma species research and implications
- Parasitic infections in humans and animals
- Cancer therapeutics and mechanisms
- Insect Pest Control Strategies
- Quinazolinone synthesis and applications
- Inflammasome and immune disorders
- Morinda citrifolia extract uses
- Biochemical and Molecular Research
- Food Allergy and Anaphylaxis Research
- Ferrocene Chemistry and Applications
- Healthcare Regulation
Universidade Federal do Triângulo Mineiro
2019-2024
Universidade de Uberaba
2019-2024
Villares Metals (Brasil)
2009
The constant evolution of bacteria makes the search for new and effective bactericidal agents essential. In this context, developing antibacterial compounds with luminescent properties offers a promising strategy to investigate intracellular biochemical processes while simultaneously assessing drug's effects. present work, coordination polymers composition [{M(L1)2}{M(L1)(H2O)2}]n (M = Sm3+, Gd3+, Yb3+) were obtained from reactions their respective lanthanide salts 1.5 equivalent...
This study aimed to characterize the immobilization of novel JIChis-2 peptide on Ti-6Al-4V alloy, widely used in biomedical sector. The antimicrobial activity was evaluated Gram-negative bacterium E. coli. Its occurred by inducing formation covalent bonds between N-terminus peptides and surface previously submitted acrylic acid polymerization via PECVD technique. Coated uncoated surfaces were characterized FTIR, AFM, SEM EDX. Studies global localized corrosion carried out, seeking explore...
Leishmaniasis is a group of parasitic diseases with the potential to infect more than 1 billion people; however, its treatment still old and inadequate. In order contribute changing this view, work consisted development complexes derived from MI metal ions thioureas, aiming obtain leishmanicidal agents. The thiourea ligands (HLR) were obtained by reactions p-toluenesulfohydrazide R-isothiocyanates used in complexation AgI AuI, leading formation composition [M(HLR)2]X (M = Ag or Au; X NO3-...
Tegumentary leishmaniasis (TL) is caused by parasites of the genus Leishmania. Leishmania braziliensis (L.b) one most clinically relevant pathogens that affects skin and mucosa, causing single or multiple disfiguring life-threatening injuries. Even so, few treatment options for patients have significant toxicity, high dropout rates, cost, emergence resistant strains, which implies need studies to promote new better treatments combat disease. Zinc oxide nanocrystals are microbicidal...
Biomedical engineering has been constantly looking for the development of new materials that have bioactive surfaces and are responsible bone formation, induce osteoblast differentiation present antibacterial properties. Here we innovative applied research to evaluate influence niobium pentoxide thin films (Nb2O5) deposited on surface a Ti-6Al-4V alloy via reactive sputtering technique activity, cellular proliferation MC3T3 cells biomineralization capacity. The results obtained in showed...
COVID-19, also known as coronavirus disease 2019, is an infectious viral caused by SARS-CoV-2, a novel coronavirus. Since its emergence, epidemiology has been explored; however, for some regions of the world, COVID-19’s behavior, incidence, and impact remain unclear. In continental nations like Brazil, this lack knowledge results in nonuniform control, prevention, treatment measures, which can be controversial locations. This study aimed to describe epidemiological profile patients with...
Chagas disease is a neglected tropical caused by the parasite Trypanosoma cruzi. Despite efforts and distinct methodologies, search of antigens for diagnosis, vaccine, drug targets still needed. The present study aimed at identifying possible that could be used drugs against T. cruzi using reverse vaccinology molecular docking. genomes 28 strains available in GenBank (NCBI) were to obtain genomic core. Then, subtractive genomics was carried out identify nonhomologous genes host A total 2630...
Biomedical engineering has been constantly looking for the development of new materials that have bioactive surfaces and are responsible bone formation, induce osteoblast differentiation present antibacterial properties. Here, we innovative applied research to evaluate influence niobium pentoxide thin films (Nb2O5) deposited on surface a Ti-6Al-4V alloy via reactive sputtering technique activity, cellular proliferation MC3T3 cells biomineralization capacity. Results demonstrated improved...
Abstract Human neurocysticercosis (NCC) is a worldwide neglected disease caused by Taenia solium metacestode and responsible for various complications neurological disorders. This study aimed to evaluate the use of specific immunoglobulin Y (IgY) produced laying hens immunized with hydrophobic fraction crassiceps metacestodes (hF Tc ) in NCC diagnosis. Egg yolk IgY antibodies were fractionated, purified characterized. Enzyme-linked immunosorbent assay (ELISA) was carried out production...
Neurocysticercosis (NCC) is a neglected tropical disease and its diagnosis still challenge due to non-specific manifestations. Neuroimaging techniques are used in the of NCC, however, high cost these methods advantages presented use immunological tests, such as ease performance satisfactory results, immunoassays commonly detect antibodies against Taenia sp. antigens. The aim present study was produce, characterize apply specific polyclonal immunoglobulin Y (IgY) anti-Taenia crassiceps...
Dendritic cells (DCs) are a type of antigen-presenting that play an important role in the immune response against Trypanosoma cruzi, causative agent Chagas disease. In vitro and vivo studies have shown modulation these by this parasite can directly affect innate acquired host order to facilitate its biological cycle spreading species. Many show mechanisms which T. cruzi modulates DCs, but interaction with Mexican strains such as Ninoa INC5 has not yet been properly investigated. Here, we...
<title>Abstract</title> The aim of this case report is to record the finding leishmaniasis-causing parasites in mesenchymal stem cells from dogs a non-endemic area, which were negative when submitted RIFI and ELISA tests, fact that had not been documented until now. This demonstrates widely distributed lethal zoonosis can escape traditional means diagnosis cell therapy has potential be source transmission disease. Although relative safety presumed, possible risks associated with its use,...
Background/Objectives: Cytokine storm in severe COVID-19 is responsible for irreversible tissue damage and death. Soluble mediators from the TNF superfamily, their correlation with clinical outcome, use of receptors as a potent predictor outcome were evaluated. Methods: Severe patients had levels soluble superfamily quantified categorized according to (death versus survival). Statistical modeling was performed predict outcomes. Results: have elevated serum superfamily. Regardless sex age,...
Noni, also known as Morinda citrifolia, is a plant that has been widely used for treating various pathologies due to its allegedly anti-inflammatory and immunomodulating properties. Macrophages monocytes are critical immune cells initiate inflammation generate an response against aggressors, regardless of their causative agent. However, it not well investigated how noni fruit components affect the behavior or phenotype these cells. Hence, studies in this direction could potentially...