A5066389055- Genomics and Phylogenetic Studies
- Biochemical and Structural Characterization
- Herpesvirus Infections and Treatments
- Research on Leishmaniasis Studies
- Sex work and related issues
- Reproductive tract infections research
- Bartonella species infections research
- RNA and protein synthesis mechanisms
- Bacterial Infections and Vaccines
- Biochemical and Molecular Research
- Microbial infections and disease research
- Trypanosoma species research and implications
- T-cell and B-cell Immunology
- Vector-borne infectious diseases
- Syphilis Diagnosis and Treatment
- Immune Cell Function and Interaction
Universidade Federal do Triângulo Mineiro
2020-2021
Universidade Federal de Minas Gerais
2020-2021
Genoa (Brazil)
2009
Biotech (Brazil)
2009
Genes encoding killer cell immunoglobulin-like receptors (KIRs) are variable among individuals. Sequence-specific primer-directed polymerase chain reaction (PCR) amplification (PCR-SSP) and sequence-specific oligonucleotide hybridization of the PCR-amplified products (PCR-SSO) methods currently used to characterize diversity KIR gene content. Both these include time-consuming post-PCR analyses. Here, we developed a real-time PCR method that identifies presence or absence 16 genes during...
Spirochetal organisms of the Treponema genus are responsible for causing Treponematoses. Pathogenic treponemes is a Gram-negative, motile, spirochete pathogen that causes syphilis in human. pallidum subsp. endemicum (TEN) endemic (bejel); T. (TPA) venereal syphilis; pertenue (TPE) yaws; and Ccarateum pinta. Out these four high morbidity diseases, mediated by sexual contact; other three diseases transmitted close personal contact. The global distribution alarming there an increasing need...
Chagas disease is a neglected tropical caused by the parasite Trypanosoma cruzi. Despite efforts and distinct methodologies, search of antigens for diagnosis, vaccine, drug targets still needed. The present study aimed at identifying possible that could be used drugs against T. cruzi using reverse vaccinology molecular docking. genomes 28 strains available in GenBank (NCBI) were to obtain genomic core. Then, subtractive genomics was carried out identify nonhomologous genes host A total 2630...
Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis, Gram-negative bacterium described over century ago. Despite broad vaccine coverage and treatment options, the remerging as public health problem especially in infants older children. Recent data indicate re-emergence of related to bacterial resistance immune defences decreased effectiveness, which obviously suggests need new effective vaccines drugs. In an attempt contribute with solutions this great...
The genus Rickettsia belongs to the Proteobacteria phylum and these bacteria infect animals humans causing a range of diseases worldwide. is divided into 4 groups despite public health threat knowledge accumulated so far, mandatory intracellular behaviour limitation for in vitro culture makes it difficult create new vaccines drug targets bacteria. In an attempt overcome limitations, pan-genomic approaches has used 47 genomes Rickettsia, order describe species similarities genomics islands....