A5026509529- Acute Myocardial Infarction Research
- Canadian Identity and History
- Erythropoietin and Anemia Treatment
- Cardiac Imaging and Diagnostics
- Blood transfusion and management
- Artificial Intelligence in Healthcare and Education
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Machine Learning in Healthcare
- Cardiac Health and Mental Health
- Pharmacology and Obesity Treatment
- Artificial Intelligence in Healthcare
- Pain Management and Opioid Use
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Health Systems, Economic Evaluations, Quality of Life
- Pharmacological Effects and Toxicity Studies
- Blood donation and transfusion practices
- Hemoglobinopathies and Related Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cancer survivorship and care
- Economic and Financial Impacts of Cancer
- Forensic Toxicology and Drug Analysis
- Social Sciences and Governance
Flinders Medical Centre
2025
Flinders University
2017-2025
The University of Adelaide
2006
High-sensitivity troponin assays promise earlier discrimination of myocardial infarction. Yet, the benefits and harms this improved discriminatory performance when incorporated within rapid testing protocols, with respect to subsequent clinical events, has not been evaluated in an in-practice patient-level randomized study. This multicenter study noninferiority a 0/1-hour high-sensitivity cardiac T (hs-cTnT) protocol comparison 0/3-hour masked hs-cTnT patients suspected acute coronary...
Menopause is a biological process experienced by all people assigned female at birth. A significant number of women experience mental ill health related to the major brain gonadal hormone shifts that occur in their midlife. There poor understanding and management complex issues, with changes receiving little formal attention. The current treatment advice manage this special type same way managed. This leads outcomes for families. Many leave workforce earlier than expected due...
<h3>Importance</h3> Although international guidelines recommend use of the Global Registries Acute Coronary Events (GRACE) risk score (GRS) to guide acute coronary syndrome (ACS) treatment decisions, prospective utility GRS in improving care and outcomes is unproven. <h3>Objective</h3> To assess effect routine implementation on guideline-indicated treatments clinical hospitalized patients with ACS. <h3>Design, Setting, Participants</h3> Prospective cluster (hospital-level) randomized...
High-sensitivity troponin assays are increasingly being adopted to expedite evaluation of patients with suspected acute coronary syndromes. Few direct comparisons have examined whether the enhanced performance these at low concentrations leads changes in care that improves longer-term outcomes. This study evaluated late outcomes participants managed under an unmasked 0/1-hour high-sensitivity cardiac T (hs-cTnT) protocol compared a 0/3-hour masked hs-cTnT protocol.We conducted multicenter...
Data sharing is essential for promoting scientific discoveries and informed decision-making in clinical practice. In 2013, PhRMA/EFPIA recognised the importance of data supported initiatives to enhance trial transparency promote advancements. However, despite these commitments, recent investigations indicate significant scope improvements by pharmaceutical industry. Drawing on a decade literature policy developments, this article presents perspectives from multidisciplinary team researchers,...
Background:Artificial intelligence (AI) has revolutionised healthcare by enhancing diagnostic accuracy and supporting clinical decision-making, particularly in emergency departments (EDs). RAPIDx_AI is designed to assist ED clinicians interpreting cardiac biomarkers for suspected myocardial infarction (MI). However, user-centred evaluations of its effectiveness real-world settings remain limited.Objective:To evaluate the using PROLIFERATE_AI framework, focusing on constructs such as...
High-sensitivity cardiac troponin strategies can provide risk stratification in patients with suspected acute coronary syndrome (ACS) the emergency department (ED). This study evaluated whether clinical scoring improves classification performance of a rule-out profile ACS. Patients presenting to ED ACS as part RAPID-TnT trial randomized intervention arm were included. Results ≥5 ng/L available for all participants this analysis. We Thrombolysis In Myocardial Infarction (TIMI) score, History...
There is evidence that the apparent oral clearance of rac-methadone induced during early phase methadone maintenance treatment. However, it not known if this due to changes in bioavailability or phenomenon stereoselective. This knowledge can be obtained by administering a dose stable-labeled at selected times ongoing Therefore, authors developed stereoselective high performance liquid chromatography-atmospheric pressure chemical ionization mass-spectrometry assay for quantification...
Background: Functional testing for acute chest pain assessment is a common practice that has not been re-examined in the era of high-sensitivity cardiac troponin. This population poses significant analytical dilemma physicians to achieve accurate diagnosis, balanced against inherent risks hospital admission and invasive downstream testing. single-centre study evaluated outcomes patients who underwent assessment, whose initial diagnosis was consistent with MI, comparing subsequent functional...
Co-editors’ Note Erin Morton and Peter L. Twohig THE SPRING 2023 ISSUE IS FIRST FULLY DIGITAL EDITION OF ACADIENSIS. We face a changing world when it comes to publishing moving towards more accessible, digital, open access formats. From political perspective, the goal of Acadiensis has always been publish finest scholarship on Atlantic region, while making space for new analytical paths. For than 50 years, continued reach audiences. this issue with research article that examines Acadian...
Co-editors' Note, and: Note des codirecteurs Peter L. Twohig and Erin Morton THE AUTUMN 2023 ISSUE ILLUSTRATES HOW Acadiensis continues to respond the challenges facing scholarly publication in Canada. There is no shortage of issues, including a changing funding landscape, uncertainty over open access, changes leadership team that guides Acadiensis. We said goodbye board members Greg Linda Kealey, who have steered Editorial Board as Chair Nominating Committee Chair, respectively, for many...
A Note from the Co-Editors Erin Morton and Peter L. Twohig THIS IS THE FINAL PRINT EDITION OF ACADIENSIS. After 51 years of publishing some finest scholarship focused on Atlantic region, Editorial Board consulted with subscribers librarians decided in June 2022 to transition a fully digital journal. This decision was guided by several intersecting factors values. One most important is that publication will save costs help ensure Acadiensis has bright future. Another factor collective effort...
Co-editors' Note Erin Morton and Suzanne HAPPY BIRTHDAY TO US! This autumn it is 50 years since the "new" Acadiensis began publication in 1971, with 95 pages that included an introduction by Acadiensis's founding editor Phil Buckner (two into his UNB career one year from PhD), three research articles, a report Provincial Archives of New Brunswick, document analysis, review essay on recent regional literature. The authors articles ranged stage emerging to near retiree: E.R. Forbes was still...
Note des codirecteurs Erin Morton and Suzanne JOYEUX ANNIVERSAIRE À NOUS! Il y a 50 ans cet automne que la « nouvelle » revue Acadiensis faisait paraître, en 1971, son tout premier numéro de 95 pages comprenant une introduction du directeur fondateur d'Acadiensis, Phil Buckner (deux après le début sa carrière à l'UNB et un an avant l'obtention doctorat), trois articles recherche, rapport Archives provinciales Nouveau-Brunswick, document d'analyse note critique sur littérature régionale...