A5042504396- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Pelvic and Acetabular Injuries
- Diverticular Disease and Complications
- Pressure Ulcer Prevention and Management
- Hernia repair and management
- Enhanced Recovery After Surgery
- Bladder and Urothelial Cancer Treatments
- Pregnancy-related medical research
- Frailty in Older Adults
- Patient-Provider Communication in Healthcare
- Stoma care and complications
- Maternal and Perinatal Health Interventions
- Surgical Simulation and Training
- Ureteral procedures and complications
- Sexual function and dysfunction studies
- Patient Satisfaction in Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Thermoregulation and physiological responses
- Endometriosis Research and Treatment
- Cancer survivorship and care
- Urological Disorders and Treatments
- Anatomy and Medical Technology
University of Pennsylvania
2016-2025
Philadelphia University
2010-2024
Hospital of the University of Pennsylvania
2014-2024
University of Pennsylvania Health System
2024
Island Institute
2023
Institute for Female Pelvic Medicine and Reconstructive Surgery
2005-2021
Kaiser Permanente
2021
California Pacific Medical Center
2018
University of Alabama at Birmingham
2014-2018
Brown University
1999-2018
<h3>Importance</h3> Women with refractory urgency urinary incontinence are treated sacral neuromodulation and onabotulinumtoxinA limited comparative information. <h3>Objective</h3> To assess whether is superior to in controlling episodes of incontinence. <h3>Design, Setting, Participants</h3> Multicenter open-label randomized trial (February 2012-January 2015) at 9 US medical centers involving 381 women <h3>Interventions</h3> Cystoscopic intradetrusor injection 200 U (n = 192) or 189)....
Importance Transvaginal surgery is commonly performed to treat pelvic organ prolapse. Little research focuses on how sexual function relates clitoral anatomy after vaginal despite the clitoris’ role in response. Objective To determine postoperative associated with features (size, position, shape). Design, Setting, and Participants This was a cross-sectional ancillary study of magnetic resonance imaging (MRI) data from Defining Mechanisms Anterior Vaginal Wall Descent (DEMAND) study. The...
Objective: To determine whether there is an association in women between caffeine intake and risk for detrusor instability. Methods: Women were included if they had symptoms of urinary incontinence, completed a 48-hour voiding diary detailing fluid intake, undergone standardized multichannel urodynamics. The study group 131 with instability on provocative cystometry maximum urethral closure pressure greater than 20 cm water. control 128 without For statistical comparison, divided into the...
In Brief OBJECTIVE: To construct and validate a prediction model for estimating the risk of de novo stress urinary incontinence (SUI) after vaginal pelvic organ prolapse (POP) surgery compare it with predictions using preoperative testing expert surgeons' predictions. MATERIALS AND METHODS: Using data set (n=457) from Outcomes Following Vaginal Prolapse Repair Midurethral Sling trial, 12 clinical predictors SUI was constructed. De determined by Pelvic Floor Distress Inventory responses...
We compared sexual function in women with pelvic organ prolapse to that without prolapse.We collected data using a standardized, validated, condition specific questionnaire. The study group consisted of 30 and it was unmatched controls evidence prolapse.The 2 groups were similar age, race, parity postmenopausal hormone use. Subjects the more likely have undergone previous surgery. Mean total Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire scores +/- SD lower (81.4...
We identify genetic variants associated with urgency urinary incontinence in postmenopausal women. A 2-stage genome-wide association analysis was conducted to incontinence. The WHI GARNET substudy 4,894 genotyped post-reproductive white women randomly split into independent discovery and replication cohorts. Genome-wide imputation performed using IMPUTE2 the 1000 Genomes ALL Phase I integrated variant set as a reference. Controls reported no at enrollment or followup. Cases monthly greater...
To determine whether percutaneous tibial nerve stimulation (PTNS) is superior to sham for the treatment of fecal incontinence (FI) in women refractory first-line treatments. Women aged 18 years or older with ≥3 months moderate-to-severe FI that persisted after a 4-week run-in phase were randomized 2:1 (PTNS:sham stimulation) 12 weekly 30-minute sessions this multicenter, single-masked, controlled superiority trial. The primary outcome was change from baseline severity measured by St. Mark...
We determined the relationship of preoperative functional status to postoperative morbidity after pelvic organ prolapse surgery in women older than 60 years.We performed a retrospective cohort study 223 years who underwent for stage II or greater prolapse. Our exposure was status, defined as American Society Anesthesiologists (ASA) physical class. compared outcomes (length stay medical facility, and number severity complications) with low (ASA class III) those high classes I II). association...
To investigate the relationship between pontine lesion characteristics on MRI and lower urinary tract symptoms (LUTS) in patients with multiple sclerosis (MS).We performed a prospective cohort study of MS LUTS who were undergoing brain/spine MRI. Patients administered American Urological Association Symptom Score (AUA-SS), Medical, Epidemiologic, Social Aspects Aging questionnaire (MESA), Urogenital Distress Inventory (UDI-6), underwent Kurtzke Expanded Disability Status Scale (EDSS) scoring...