Alayne D. Markland

ORCID: 0000-0002-6567-6744
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About
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Research Areas
  • Pelvic floor disorders treatments
  • Urinary Bladder and Prostate Research
  • Urinary Tract Infections Management
  • Anorectal Disease Treatments and Outcomes
  • Diverticular Disease and Complications
  • Healthcare Systems and Public Health
  • Frailty in Older Adults
  • Sleep and related disorders
  • Pressure Ulcer Prevention and Management
  • Gastrointestinal motility and disorders
  • Pharmaceutical Practices and Patient Outcomes
  • Emergency and Acute Care Studies
  • Prostate Cancer Diagnosis and Treatment
  • Geriatric Care and Nursing Homes
  • Climate Change and Health Impacts
  • Health disparities and outcomes
  • Hernia repair and management
  • Stoma care and complications
  • Health and Wellbeing Research
  • Bladder and Urothelial Cancer Treatments
  • Patient Satisfaction in Healthcare
  • Enhanced Recovery After Surgery
  • Migraine and Headache Studies
  • Clinical practice guidelines implementation
  • Maternal and Perinatal Health Interventions

University of Alabama at Birmingham
2016-2025

Birmingham VA Medical Center
2016-2025

Geriatric Research Education and Clinical Center
2015-2024

University of Minnesota
2024

Sage Therapeutics (United States)
2024

Atlanta VA Health Care System
2024

St. Vincent's Birmingham
2010-2024

John Wiley & Sons (United States)
2019-2023

GTx (United States)
2022

Park University
2018-2020

To estimate the prevalence and trends of these pelvic floor disorders in U.S. women from 2005 to 2010.We used National Health Nutritional Examination Survey 2005-2006, 2007-2008, 2009-2010. A total 7,924 nonpregnant (aged 20 years or older) were categorized as having: urinary incontinence (UI)-moderate severe (3 higher on a validated UI severity index, range 0-12); fecal incontinence-at least monthly (solid, liquid, mucus stool); organ prolapse-seeing feeling bulge. Potential risk factors...

10.1097/aog.0000000000000057 article EN Obstetrics and Gynecology 2013-12-09

No AccessJournal of UrologyAdult Urology1 Aug 2011Prevalence and Trends Urinary Incontinence in Adults the United States, 2001 to 2008 Alayne D. Markland, Holly E. Richter, Chyng-Wen Fwu, Paul Eggers, John W. Kusek MarklandAlayne Markland Birmingham/Atlanta Geriatric Research, Education Clinical Center, Department Veterans Affairs Medical University Alabama at Birmingham, Division Gerontology, Geriatrics Palliative Care, Medicine, , RichterHolly Richter Woman's Pelvic Medicine Reconstructive...

10.1016/j.juro.2011.03.114 article EN The Journal of Urology 2011-06-25

In August 2013, the National Institutes of Health sponsored a conference to address major gaps in our understanding epidemiology, pathophysiology, and management fecal incontinence (FI) identify topics for future clinical research. This article is first two-part summary those proceedings. FI common symptom, with prevalence that ranges from 7 15% community-dwelling men women, but it often underreported, as providers seldom screen patients do not volunteer even though symptoms can have...

10.1038/ajg.2014.396 article EN The American Journal of Gastroenterology 2014-12-23

Epidemiological studies support an association of self-defined constipation with fiber and physical activity, but not liquid intake. The aims this study were to assess the prevalence associations dietary intake constipation.Analyses based on data from 10,914 adults (≥20 years) 2005-2008 cycles National Health Nutrition Examination Surveys. Constipation was defined as hard or lumpy stools (Bristol Stool Scale type 1 2) "usual most common stool type." Dietary total moisture content obtained...

10.1038/ajg.2013.73 article EN The American Journal of Gastroenterology 2013-04-09

OBJECTIVE: To evaluate the prevalence and effect of overactive bladder (OAB) on healthcare‐seeking behavior, mental health, generic condition‐specific health‐related quality life (HRQL) in older adults. DESIGN: Secondary analysis U.S. sample Epidemiology Lower Urinary Tract Symptoms (EpiLUTS) study—a population‐based, cross‐sectional, Internet‐based survey. SETTING: Community. PARTICIPANTS: Two thousand four hundred eighty‐five men 2,877 women aged 65 older. MEASUREMENTS: Prevalence HRQL...

10.1111/j.1532-5415.2011.03492.x article EN Journal of the American Geriatrics Society 2011-06-30

Abstract Aims To evaluate validity and responsiveness of PFDI PFIQ short forms across four multi‐center studies develop conversion formulas between long versions. Methods 1,006 participants in prospective pelvic floor disorders completed versions the PFDI, PFIQ, SF‐36 (or SF‐12) at baseline 3 12 months after treatment. Responses were used to calculate scores for We calculated correlations scale using Pearson's correlation coefficient compared their relative standardized response mean....

10.1002/nau.20934 article EN Neurourology and Urodynamics 2011-02-22

To determine the incidence of fecal incontinence (FI) in community-dwelling older adults and identify risk factors associated with incident FI.Planned secondary analysis a longitudinal, population-based cohort study.Three rural two urban Alabama counties (in-home assessments 2000-2005).Stratified random sample 1,000 Medicare beneficiaries: 25% African-American men, white women, aged 65 older. Eligible participants for this were continent at baseline 4 years later (n=557).FI was defined as...

10.1111/j.1532-5415.2010.02908.x article EN Journal of the American Geriatrics Society 2010-06-02

We estimated the prevalence of urinary incontinence in United States adult male population and identified associated factors.Data were analyzed for 5,297 men 20 years old or older who participated 2005 to 2006 2007 2008 cycles National Health Nutrition Examination Survey, a cross-sectional, nationally representative survey noninstitutionalized population. Urinary (score 3 greater on validated severity index, indicating moderate severe leakage) was assessed. Potential factors included age,...

10.1016/j.juro.2010.05.025 article EN The Journal of Urology 2010-07-21

Urinary incontinence is a common geriatric syndrome that affects at least 1 in 3 older women and can greatly diminish quality of life. Incontinence has been associated with increased social isolation, falls, fractures, admission to long-term care facilities. Often unreported thus untreated, it important include as part the review systems for all women. Using case Mrs F, we highlight chronicity discuss evidence base evaluation women, proper initial diagnosis type incontinence-stress, urgency,...

10.1001/jama.2010.749 article EN JAMA 2010-06-01

Objectives To compare the effectiveness of behavioral treatment with that antimuscarinic therapy in men without bladder outlet obstruction who continue to have overactive ( OAB ) symptoms alpha‐blocker therapy. Design The Male Overactive Bladder Treatment Veterans (MOTIVE) Trial was a two‐site randomized, controlled, equivalence trial 4‐week run‐in. Setting Affairs Medical Center outpatient clinics. Participants Volunteer sample 143 aged 42 88 continued urgency and more than eight voids per...

10.1111/j.1532-5415.2011.03724.x article EN Journal of the American Geriatrics Society 2011-11-07

Objectives To estimate the prevalence of urinary ( UI ), fecal FI and dual incontinence DI ) to identify shared factors associated with each type in older U.S. women men. Design Population‐based cross‐sectional study. Setting National Health Nutrition Examination Survey NHANES , 2005–2010). Participants Women men aged 50 older. Measurements was defined as moderate severe (≥3 on a validated severity index, range 0–12); at least monthly loss solid, liquid, or mucus stool; presence . Results...

10.1111/jgs.13385 article EN Journal of the American Geriatrics Society 2015-05-01

Fecal incontinence is a devastating condition with few US Food and Drug Administration-approved pharmacologic treatment options. Loperamide psyllium, both first-line treatments, have different mechanisms of action without any comparative data.The purpose this study was to examine the effectiveness tolerability loperamide compared psyllium for reducing fecal incontinence. We hypothesized that fiber supplementation would be more effective than episodes fewer adverse effects.We conducted...

10.1097/dcr.0000000000000442 article EN Diseases of the Colon & Rectum 2015-09-05

First-line behavioral and drug therapies for overactive bladder (OAB) symptoms in men are effective but not usually curative.To determine whether combining improves outcomes compared with each therapy alone OAB to compare 3 sequences implementing combined therapy.In this 3-site, 2-stage, 3-arm randomized clinical trial, participants were 6 weeks of alone, or followed by step-up all groups. Participants recruited from outpatient clinics included community-dwelling 40 years older urinary...

10.1001/jamainternmed.2019.6398 article EN JAMA Internal Medicine 2020-01-13

We determined the incidence and predictors of incident urinary incontinence over 3 years in community dwelling older adults.

10.1016/j.juro.2007.11.069 article EN The Journal of Urology 2008-03-06

To determine the prevalence and correlates of nocturia in community-dwelling older adults.Planned secondary analysis cross-sectional data from University Alabama at Birmingham Study Aging population-based survey.Participants' homes.One thousand adults (aged 65-106) recruited Medicare beneficiary lists between 1999 2001. The sample was selected to include 25% each African-American women, men, white men.In-person interviews included sociodemographic information, medical history, Mini-Mental...

10.1111/j.1532-5415.2010.02822.x article EN Journal of the American Geriatrics Society 2010-04-14

Background Behavioral intervention outcomes for urinary incontinence (UI) depend on active patient participation. Objective The purpose of this study was to describe adherence behavioral interventions (pelvic-floor muscle [PFM] exercises, UI prevention strategies, and delayed voiding), patient-perceived exercise barriers, predictors in women with urge-predominant UI. Design This a prospectively planned secondary data analysis from 2-stage, multicenter, randomized clinical trial. Patients...

10.2522/ptj.20080387 article EN Physical Therapy 2010-07-29
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