Christopher Sexton

ORCID: 0000-0003-0928-214X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Pelvic floor disorders treatments
  • Urinary Bladder and Prostate Research
  • Urinary Tract Infections Management
  • Viral Infections and Vectors
  • Vector-borne infectious diseases
  • Yersinia bacterium, plague, ectoparasites research
  • Vector-Borne Animal Diseases
  • Mosquito-borne diseases and control
  • Zoonotic diseases and public health
  • Child Abuse and Trauma
  • Sexual function and dysfunction studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Vibrio bacteria research studies
  • Obesity, Physical Activity, Diet
  • Gastrointestinal motility and disorders
  • Intellectual Property and Patents
  • Copyright and Intellectual Property
  • Biotechnology and Related Fields
  • Family and Disability Support Research
  • Bacillus and Francisella bacterial research
  • Patient Satisfaction in Healthcare
  • Early Childhood Education and Development
  • Meta-analysis and systematic reviews
  • Intellectual Property Law

Centers for Disease Control and Prevention
2008-2024

University of Missouri–Kansas City
2022

Center for Anxiety and Depression
2019-2022

National Center for Emerging and Zoonotic Infectious Diseases
2015-2021

Children's Mercy Hospital
2017-2019

Access to Wholistic and Productive Living Institute
2018

Ithaka Harbors
2014-2018

Mercy Hospital
2018

Seton Medical Center Austin
2018

Baylor College of Medicine
2018

OBJECTIVES To examine the effect overactive bladder (OAB) and other lower urinary tract symptoms (LUTS) on health‐related quality of life (HRQoL) in a population sample, as OAB often occurs conjunction with many LUTS. SUBJECTS AND METHODS A nested case‐control analysis was performed men women (cases) without (controls) OAB, from EPIC study. assessed using 2002 International Continence Society definitions. Based their responses to questions about LUTS, cases were classified into five groups;...

10.1111/j.1464-410x.2008.07601.x article EN BJU International 2008-05-01

OBJECTIVE To estimate and compare the prevalence associated bother of lower urinary tract symptoms (LUTS) in general populations USA, UK Sweden using current International Continence Society (ICS) definitions, as no previous population‐based studies evaluating LUTS 2002 ICS have been conducted. SUBJECTS AND METHODS This cross‐sectional, population‐representative survey was conducted via Internet Sweden. Members Internet‐based panels were randomly selected to receive an e‐mailed invitation...

10.1111/j.1464-410x.2009.08427.x article EN BJU International 2009-03-05

OBJECTIVE To evaluate the impact of lower urinary tract symptoms (LUTS) on urinary‐specific health‐related quality life (HRQL), generic health indices, depression and anxiety in a population‐representative sample men women, as research has linked LUTS with reduced HRQL depression, but little is known about effects individual HRQL, anxiety. SUBJECTS AND METHODS A cross‐sectional survey was conducted via Internet USA, UK Sweden. Participants rated frequency symptom‐specific bother...

10.1111/j.1464-410x.2009.08371.x article EN BJU International 2009-03-19

Study Type – Symptom prevalence (prospective cohort) Level of Evidence 1b OBJECTIVE • To examine the and burden overactive bladder (OAB) with bother in UK Sweden compared to OAB without no/minimal OAB/lower urinary tract (LUTS) symptoms, respectively. PATIENTS AND METHODS A cross‐sectional population‐representative survey was conducted via Internet UK, USA. Participants rated frequency LUTS. Patient outcomes included Overactive Bladder Questionnaire Short Form, Perception Condition, Form‐12,...

10.1111/j.1464-410x.2010.10013.x article EN BJU International 2011-03-03

Abstract Aims To estimate the prevalence of LUTS and OAB in a large, ethnically diverse US study. Methods This cross‐sectional, population‐representative survey was conducted via Internet among 10,000 men women aged 18–70 (2,000 African‐Americans [AA], 2,000 Hispanics, 6,000 whites). The tool assessed how often participants experienced during past 4 weeks on five‐point Likert scale. defined by presence urinary urgency ≥ “sometimes” or “often,” and/or incontinence (UUI). Descriptive...

10.1002/nau.22295 article EN Neurourology and Urodynamics 2012-07-27

Abstract The aim of the current study was to identify and evaluate cutoffs for mild, moderate, severe ranges Hamilton Anxiety Rating Scale (HAM‐A) scores. Data were from a four‐week randomized trial treatment generalized anxiety disorder. Measures included HAM‐A, SF‐36, Hospital Depression (HADS), Clinical Global Impressions Severity (CGI‐S) scale. HAM‐A identified based on literature review, expert panel input, MANOVA models. optimal cutoff set evaluated association with clinician CGI‐S...

10.1002/mpr.323 article EN International Journal of Methods in Psychiatric Research 2010-08-18

OBJECTIVE To assess the (i) overlap between voiding, storage, and postmicturition symptoms; (ii) relative effect of bother implications for treatment seeking within these symptom groups, using data from EpiLUTS study. SUBJECTS AND METHODS This cross‐sectional population‐representative survey was conducted via Internet in USA, UK Sweden. Participants were asked to rate frequency symptom‐specific individual LUTS. Descriptive statistics used examine differences International Continence Society...

10.1111/j.1464-410x.2009.08369.x article EN BJU International 2009-03-19

OBJECTIVE To explore the risk factors and comorbid conditions associated with subgroups of lower urinary tract symptoms (LUTS) in men women aged ≥40 years three countries, using data from EpiLUTS study, as LUTS are common amongst increase prevalence age. SUBJECTS AND METHODS This cross‐sectional, population‐representative survey was conducted via Internet USA, UK Sweden. Participants were asked to rate how often they experienced individual during past 4 weeks on a 5‐point Likert scale. Eight...

10.1111/j.1464-410x.2009.08438.x article EN BJU International 2009-03-19

OBJECTIVE: To evaluate the prevalence and effect of overactive bladder (OAB) on healthcare‐seeking behavior, mental health, generic condition‐specific health‐related quality life (HRQL) in older adults. DESIGN: Secondary analysis U.S. sample Epidemiology Lower Urinary Tract Symptoms (EpiLUTS) study—a population‐based, cross‐sectional, Internet‐based survey. SETTING: Community. PARTICIPANTS: Two thousand four hundred eighty‐five men 2,877 women aged 65 older. MEASUREMENTS: Prevalence HRQL...

10.1111/j.1532-5415.2011.03492.x article EN Journal of the American Geriatrics Society 2011-06-30

The Overactive Bladder Questionnaire (OAB-q) has demonstrated robust psychometric properties in continent and incontinent OAB patients. However, there is a need for short-form of this instrument settings where completing the full OAB-q may be too burdensome. purpose manuscript to describe validation short-form.Three studies were used derive validate SF: 12-week, multicenter, open-label clinical trial tolterodine ER (N = 865 [I-OAB]; "Noble Nested Case-Control" [NCC] study; N 523 healthy...

10.1002/nau.22559 article EN Neurourology and Urodynamics 2014-01-13

Acute febrile illness (AFI) is associated with substantial morbidity and mortality worldwide, yet an etiologic agent often not identified. Convalescent-phase serology impractical, blood culture slow, many pathogens are fastidious or impossible to cultivate. We developed a real-time PCR-based TaqMan array card (TAC) that can test six eight samples within 2.5 h from sample results simultaneously detect 26 AFI-associated organisms, including 15 viruses (chikungunya, Crimean-Congo hemorrhagic...

10.1128/jcm.02257-15 article EN Journal of Clinical Microbiology 2015-10-22

The characteristics of patients who suffer from noncancer pain and opioid-induced constipation are not well understood.Cross-sectional patient survey chart review data the baseline assessment an ongoing longitudinal study in USA, Canada, Germany, UK were evaluated via descriptive statistics. Participants had confirmation daily opioid therapy ≥30 mg for ≥4 weeks self-reported constipation. Response to laxatives was defined by classifying participants into categories laxative use evaluating...

10.2147/ceor.s61602 article EN cc-by-nc ClinicoEconomics and Outcomes Research 2014-05-01

Adverse childhood experiences (ACEs), including trauma exposure, parent mental health problems, and family dysfunction, put children at risk for disrupted brain development increased later problems mortality. These negative effects may be prevented by resilience promoting environments that include protective caregiving relationships. We sought to understand (1) parents' of ACEs, (2) the perceived impact on parenting, (3) factors buffer ACEs potential impact, (4) supports services can reduce...

10.1177/1090198117752785 article EN Health Education & Behavior 2018-02-12

Abstract Aims To evaluate the relationship between body mass index (BMI) and urinary incontinence (UI) in adults ≥40 from United States, Kingdom, Sweden. Methods This was a secondary analysis of EpiLUTS—a population‐representative, cross‐sectional, Internet‐based survey conducted to assess prevalence HRQL impact symptoms. UI evaluated by LUTS Tool categorized subgroups: no UI, urgency (UUI), stress (SUI), mixed (MUI) (UUI + SUI), UUI other (OI), SUI OI, OI. Descriptive statistics were used....

10.1002/nau.22428 article EN Neurourology and Urodynamics 2013-06-18

Serological assays and a two-tiered test algorithm are recommended for laboratory confirmation of Lyme disease. In the United States, sensitivity testing using commercially available serology-based is dependent on stage infection ranges from 30% in early localized disease to near 100% late-stage Other variables, including subjectivity reading Western blots, compliance with recommendations, use different first- second-tier combinations, samples, all contribute variation performance. The...

10.1128/jcm.01409-14 article EN Journal of Clinical Microbiology 2014-08-14

<h3>Background</h3> Although respiratory symptoms are characteristic features of COPD, there is no standardised method for quantifying their severity in stable disease. <h3>Objective</h3> To evaluate the EXACT-Respiratory Symptom (E-RS) measure, a daily diary comprising 11 14 items Exacerbations Chronic Pulmonary Disease Tool (EXACT). <h3>Methods</h3> Qualitative: patient focus group and interviews to address content validity. Quantitative: secondary data analyses test reliability...

10.1136/thoraxjnl-2013-204428 article EN cc-by-nc Thorax 2014-03-04
Coming Soon ...