A5089522576- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Carbon dioxide utilization in catalysis
- Nanoparticle-Based Drug Delivery
- Advanced Drug Delivery Systems
- Additive Manufacturing and 3D Printing Technologies
- Polymer Nanocomposite Synthesis and Irradiation
- Hydrogels: synthesis, properties, applications
- Advanced Polymer Synthesis and Characterization
- Advanced Sensor and Energy Harvesting Materials
- Bone Tissue Engineering Materials
- Biopolymer Synthesis and Applications
- Folate and B Vitamins Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Cancer Treatment and Pharmacology
- Facial Rejuvenation and Surgery Techniques
- Ultrasound Imaging and Elastography
- Biochemical effects in animals
- nanoparticles nucleation surface interactions
- Photoacoustic and Ultrasonic Imaging
- Quantum Dots Synthesis And Properties
- Photochemistry and Electron Transfer Studies
- Nanoparticles: synthesis and applications
- Polymer crystallization and properties
- Porphyrin Metabolism and Disorders
Kurchatov Institute
2019-2025
Institute of Synthetic Polymeric Materials
2022-2024
Dermal fillers have gained significant attention in the field of aesthetic medicine due to their ability restore volume and correct facial wrinkles. Even though such formulations similar compositions, they can different microstructure molecular characteristics, which turn affect biodegradation profile. This study presents results an investigation physicochemical characteristics four dermal from manufacturers (Sculptra®, Gana V®, AestheFill®, Repart PLA®). The supramolecular polylactic acid...
В работе проводится исследование спектров комбинационного рассеяния (КР) света ряда материалов на основе полилактида: стереоизомеров полилактида, олигомеров L-лактида, сополимеров L-лактида и ε-капролактона, композитов поли(L-лактида) гидроксиапатита. Установлено, что по спектрам КР можно определять состав степень кристалличности широкого круга полилактида. Развитие такой методики очень важно для разработки инновационных используемых как разнообразных медицинских применений, так и, например,...
Abstract Aqueous dispersions of gold and silver nanoparticles (NPs) stabilized with sodium citrate, as well polymeric NPs based on poly(lactide- co -glycolide) (70 : 30 mol %) poly(vinyl alcohol) have been obtained. The sizes determined by transmission electron microscopy (TEM), dynamic light scattering (DLS), analytical ultracentrifugation (AUC). It has shown that the diameter both metallic particles measured TEM is significantly lower than their hydrodynamic D h DLS. Moreover, it found...
The kinetic of D,L-lactide polymerization in presence biocompatible zirconium acetylacetonate initiator was studied by differential scanning calorimetry isothermal mode at various temperatures and concentrations. enthalpy measured directly DSC cell found to be ΔH=-17.8±1.4 kJ mol-1. Kinetic curves propagation rate constants were determined for with concentrations 250-1000 ppm temperature 160-220 °C. Using model or reversible the following thermodynamic parameters calculated: activation...
Abstract Stereolithography and DLP printing attract a lot of attention in medical field as techniques for fabrication personalized implants various devices. However, there is lack photo‐curable resins biodegradable tissue engineering constructs implants. In this work UV‐curable d,l ‐lactide oligomers are presented, which can be good candidates SLA 3D printing. Linear star‐shaped (3‐ 6‐arm) methacrylated with different molecular weight synthesized cross‐linked conditions. UV‐curing performed...
Polymerization of D,L-lactide was performed in bulk at 160°C the presence bismuth (III) subsalicylate catalyst. Kinetics reaction studied by differential scanning calorimetry isothermal mode and catalyst concentrations 2500, 5000, 7500 ppm. It shown that has a high activity: under this conditions an equilibrium conversion 96% achieved 20–30 min, molecular weight resulting poly(D,L-lactide) reached 118 kDa.
Abstract In this work, the high‐frequency acoustic microscopy is applied for imaging of internal microstructure and measurement elastic characteristics biodegradable polymers based on D,L ‐lactide, L ε‐caprolactone, their copolymers. Acoustic results (images in volume values sound speed) have been supplemented by data gel permeation chromatography, differential scanning calorimetry, mechanical tensile test obtained under hydrolysis range from initial state to 8 weeks with step 2 weeks. The...
Abstract Star-shaped biodegradable poly(L-lactide)s are perspective materials with tailored properties and degradation rates which can be controlled by number length of the arms. 6-arm arm lengths from 10 to 50 units were synthesized ring-opening polymerization studied NMR, GPC DSC. The effect on electrospinning star-shaped polymers was demonstrated. Structure non-woven based PLLA its mixtures linear high molecular weight PEO studied.
Monitoring of kinetics degradation process in polymers is one the attractive possibilities applying ultrasound techniques that provide non-destructive imaging internal microstructure and measurements elastics properties. In this work biodegradable copolymers based on L,L-lactide, D,L-lactide ε-caprolactone were studied at different stages hydrolysis 37°C by high-frequency (100 200 MHz) ultrasound. Acoustic microscopy technique was developed to reveal changes bulk speed sound polymer samples...