A5089912702- Tryptophan and brain disorders
- Nigella sativa pharmacological applications
- Endometriosis Research and Treatment
- Stress Responses and Cortisol
- Global Maternal and Child Health
- Early Childhood Education and Development
- Pharmacological Effects of Natural Compounds
- Estrogen and related hormone effects
- MicroRNA in disease regulation
- Genetic Associations and Epidemiology
- Infant Development and Preterm Care
- Reproductive Health and Contraception
- Healthcare Systems and Reforms
- Child and Adolescent Psychosocial and Emotional Development
- Lipid Membrane Structure and Behavior
- COVID-19 and Mental Health
- HIV Research and Treatment
- Phytochemical Studies and Bioactivities
- Neuroendocrine regulation and behavior
- Extracellular vesicles in disease
- Inflammatory Biomarkers in Disease Prognosis
- Maternal Mental Health During Pregnancy and Postpartum
- Effects and risks of endocrine disrupting chemicals
- Sphingolipid Metabolism and Signaling
- RNA and protein synthesis mechanisms
National University of Sciences and Technology
2019-2023
University of Health Sciences Lahore
2019-2021
CMH Lahore Medical College and Institute of Dentistry
2018
University of Health Science
2018
University of Health Sciences
2018
Sir Ganga Ram Hospital
2011
Temozolomide (TMZ), the first-line chemotherapeutic drug against glioblastoma multiforme (GBM), often fails to provide desired clinical outcomes due inflammation-induced resistance amid inefficient delivery across blood-brain barrier (BBB). The current study utilized solid lipid nanoparticles (SLNPs) for targeted of TMZ GBM. After successful formulation and characterization SLNPs conjugation with (SLNP-TMZ), their in-vitro anti-cancer efficacy effect on migratory potential cancer cells were...
Inflammatory cascade plays a pivotal role in the onset and progression of major depressive disorder (MDD) glioblastoma multiforme (GBM). Therefore, questing natural compounds with anti-inflammatory activity such as diosgenin can act double-edged sword targeting cancer cancer-induced inflammation simultaneously. The blood-brain barrier limits therapeutic efficiency drugs against intracranial pathologies including depression brain cancers. Encapsulating drug molecule lipid nanoparticles...
<br><b>Background:</b> Endometriosis is one of the common causes infertility with very diverse etiology. In modern lifestyle, humans are exposed to several endocrine-disrupting chemicals (EDCs) which may lead reproductive disturbances. Diethyl hexyl phthalate (DEHP) EDCs women by use cosmetics, perfumes, food packaging, medicine, and insecticides. <b>Aim: </b> The aim this study was measure levels DEHP in diagnosed endometriosis healthy females compare these among different stages...
Global health estimates indicated approximately 322 million people living with depression. Rising cost of depressive illness treatment and non-responsiveness to existing therapies demand continued research explore new more potent therapies. Exploring the potential natural compounds for their antidepressant potentials is becoming topic interest scientists. Anti-inflammatory activity thymoquinone, active ingredient Nigella sativa, has been well documented. Current study tested thymoquinone its...
The present research aimed to study postnatal depression in pregnant mothers and find out its association with the gender of newborn fourth pregnancy. Cohort design purposive sampling technique was used. sample comprised 500 three alive female issues, taken from department gynecology obstetrics, Sir Ganga Ram Hospital, Lahore. assessment tools included a demographic questionnaire, Siddique Shah Depression Scale, Edinburgh Postnatal Scale DSM-IV-TR's criteria depression. subjects were divided...
Background: Endometriosis has a complex multifactorial pathophysiology and is leading cause of female infertility. Emerging evidence suggests the role endocrine disrupting chemicals environmental factors such as Diethyl phthalate (DEP) in disease. Aim: To investigate serum DEP levels females with infertility having endometriosis normal healthy counter parts. Methods: Married (n=50) age 20-40 years, diagnosed history >1 year infertility, were selected cases. Age matched women proven...