Abstract Background Failure mode and effects analysis (FMEA) is a prospective, team based, structured process used to identify system failures of high risk processes before they occur. Medication dispensing risky that should be analysed for its inherent risks using FMEA. The objective this study was possible failure modes, their effects, causes in the selected tertiary care hospital Methods Two independent teams (Team A Team B) pharmacists conducted FMEA two months Department Pharmacy...

<title>Abstract</title> <bold>Background:</bold> Aging is an irreversible process influenced by both internal (genetic) and external (environmental) factors. These factors contribute to differences in how individuals age. not just about a decline physical mental abilities but involves complex biological mechanisms. Two main theories explain aging: 1. Programmed Theories: Suggest that aging follows clock; 2. Error Theories Propose caused environmental damage cells, leading DNA the...

Purpose Recent studies have implicated the human cytomegalovirus (HCMV) as a possible pathogen for causing hypertension. We aimed to study association between HCMV infection and hypertension in United States National Health Nutrition Examination Survey (NHANES). Methods analyzed data on 2979 men 3324 women NHANES 1999–2002. included participants aged 16–49 years who had valid Results Of participants, 54.7% serologic evidence of 17.5% There were ethnic differences prevalence (P<0.001)...

Poor communication of medicines information to patients may cause medication errors. We assessed the completeness and readability dosing instructions provided by pharmacists on dispensing labels knowledge among their medicines.A cross sectional study was conducted in a selected teaching hospital, community pharmacy, 800 through systematic sampling method, during period 2 months. Completeness were against checklist. Patients asked read assess readability. Patient determined questionnaire....

Abstract Haemoglobin A1c (HbA1c) is a marker of glycaemic control in type 2 diabetes mellitus (T2DM). Increased waist circumference (WC) known to be associated with T2DM. Therefore, we investigated the relationship WC HbA1c and explored its optimal cutoff for identifying prediabetes risk. This study included 2339 participants between 18 84 years age [mean (SD) age, 43.5 (11.9) years] valid data on WC, related variables Shenzhen–Hong Kong United Network Cardiovascular Disease study....

There are limited studies on medication errors in South Asian and East regions. To bridge this gap, we assessed prescribing selected medicine administration among inpatients, the level of acknowledgement by specialist physicians a resource-limited hospital setting.The study was conducted two medical wards Sri Lanka. Prescribing were identified medicines prescribed latest prescription randomly inpatients. Medical notes, histories clinic notes information sources. Consistency according to...

Abstract Background ‘Screening tool of older people’s prescriptions (STOPP) and screening to alert right treatment (START)’ criteria is a useful assess the appropriateness medicines among adults. However, original STOPP/START developed in West, may not be directly applicable resource limited healthcare settings like Sri Lanka. Hence, we aimed modify (Version 2) suit Method Two investigators (a clinical pharmacologist pharmacist) reviewed flagged that were unfeasible Lanka based on their...

Purpose: Hypertension is associated with inflammation. Whether the inflammation caused by allergic diseases such as rhinitis can predispose to hypertension controversial. Therefore, we studied association between hay fever and in United States National Health Nutrition Examination Survey (NHANES).Methods: We analyzed data on 1883 men 2029 women NHANES 2005–2006. included participants aged 20 years or older who had valid hypertension.Results: 13.5% of a previous diagnosis 36.2% them...

Introduction and Objectives: Inappropriate abbreviations used in prescriptions have led to medication errors. We investigated the use of error-prone other unapproved prescriptions, assessed attitudes pharmacists on this issue. Methods: A reference list was developed. Prescriptions outpatients specialty clinic patients a teaching hospital Sri Lanka were reviewed during one month. An interviewer administered questionnaire assess pharmacists. Results: 3370 drug items (989 prescriptions)...

We describe our experience of the first 10 years at Sri Lanka Clinical Trials Registry (SLCTR).We analyzed all trial records SLCTR over study period. collected information regarding characteristics and completeness data entry in set.During period, 210 trials (63% applications) were registered with SLCTR. The number showed an increasing trend years. All registrations had complete entries for fields studied. Only 17.6% retrospectively. interventional studies, majority (87.6%) randomized...

There is a debate as to whether some types of oral leucoplakias (OL) are caused by Candida species, and they contribute the malignant transformation, associated with minority such lesions. As no detailed population analysis yeast isolates from OL available, we evaluated virulence attributes, genotypes 35 C. albicans OL, compared their 18 healthy individuals.The traits were esterase, phospholipase, proteinase, haemolysin coagulase production, phenotypic switching activity, adherence biofilm...

Abstract Background Dispensing errors, known to result in significant patient harm, are preventable if their nature is and recognized. However, there a scarcity of such data on dispensing errors particularly resource poor settings, where healthcare provided free-of-charge. Therefore, the purpose this study was determine types, prevalence selected group hospitals Sri Lanka. Methods A prospective, cross sectional, multi-center conducted, single tertiary care, two secondary care hospitals,...

The pharmacist is an important link between doctor and patient. To optimise patient care, it essential that expectations of doctors patients regarding pharmacy services are met. Hence the objective this study was to assess satisfaction levels on currently provided, their from services. This cross sectional conducted in selected clinics a university based teaching hospital. Questionnaires developed in-house by referring previously published resources, content validated group experts, face...

Background: Drug related problems (DRPs) in prescriptions could result patient harm. Objective: To assess the effectiveness of an educational workshop on detecting DRPs by a cohort community pharmacists. Methods: Pharmacists working large pharmacy chain Sri Lanka were invited for prescriptions. Participants asked to review three mock containing hypothetical before workshop. After interactive teaching session, pharmacists same again. Results: All who attended (N=58) participated. The mean...