- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Dental Radiography and Imaging
- Dental materials and restorations
- Bone Metabolism and Diseases
- Orthopaedic implants and arthroplasty
- Cleft Lip and Palate Research
- Facial Trauma and Fracture Management
- RNA modifications and cancer
- Flavonoids in Medical Research
- Magnesium Alloys: Properties and Applications
- Bone Tumor Diagnosis and Treatments
- Craniofacial Disorders and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Scientific and Engineering Research Topics
- 3D Printing in Biomedical Research
- Adrenal and Paraganglionic Tumors
- Carbon and Quantum Dots Applications
- Salivary Gland Disorders and Functions
- Advanced biosensing and bioanalysis techniques
- Advanced Materials Characterization Techniques
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Burn Injury Management and Outcomes
- Dental Anxiety and Anesthesia Techniques
Qingdao University
2016-2025
Affiliated Hospital of Qingdao University
2016-2025
Stomatology Hospital
2021
Manipulating the degradation rate of biomedical magnesium alloys poses a challenge. The characteristics microarc oxidation (MAO), prepared in phytic acid, and poly(L-lactic acid) (PLLA) composite coating, fabricated on novel Mg-1Li-1Ca alloy, were studied through field emission scanning electron microscopy (FE-SEM), probe X-ray microanalysis (EPMA), energy dispersive spectroscopy (EDS) diffraction (XRD). corrosion behaviors samples evaluated via hydrogen evolution, potentiodynamic...
Rationale: Dental implant restoration is essential for rehabilitating dentition defects. However, peri-implantitis (PI) seriously threatens the long-term stability of implants. Treating PI requires complete eradication plaque biofilm and meticulous modulation inflammatory responses. Antibacterial photodynamic therapy (aPDT) presents a promising potential in antibacterial realm. Nonetheless, traditional aPDT faces challenges such as inadequate penetration distribution photosensitizers, well...
Abstract Aims To compare the accuracy of Yakebot dental implant robotic system with that fully guided static computer‐assisted surgery (CAIS) template in edentulous implantation. Materials and Methods Thirteen patients were recruited divided into two groups: Yake group (experimental) ( n = 5) CAIS (control) 8). Postoperative cone‐beam computed tomography (CBCT) was performed immediately, 3‐dimensional positions implants obtained compared preoperative design. The comparison showed platform,...
Enhancing osteointegration of implants in osteoporosis patients is a necessity since implantations frequently fail these patients. The aim this work to study how simvastatin-strontium-hydroxyapatite coated perform rabbits with osteoporosis.Crystalline HA and Sr-HA oxide film were prepared through micro-arc oxidation. Surface characterization including morphology, roughness, element composition, phase hydrophilicity then evaluated. Simvastatin loaded on porous films immersion, the effects...
Microarc oxidation (MAO) has become a promising technique for the surface modification of implants. Therefore, aims this study were to further quantitatively and qualitatively evaluate osteointegration abilities MAO-treated smooth (SF) implants in vivo investigate areas which superiority are displayed. In rabbit model, comprehensive histomorphological, osteogenic, mineralizational, integrative assessment was performed using light microscopy, fluorescence confocal laser scanning radiographic...
The present study aimed to investigate the effect of β‑receptor blocker propranolol on early osseointegration pure titanium implants and underlying molecular regulatory mechanisms. An implant model using tibial metaphysis New Zealand rabbits was established. were divided into control low‑, medium‑ high‑dose groups. formation detected by X‑ray scanning. Mesenchymal stem cells (MSCs) osteoblasts (OBs) isolated cultured in vitro, isoproterenol supplemented simulate sympathetic action...
Abstract Background There is no data available on the long‐term outcomes of a rooted, platform‐switched, microthreaded implant with sandblasted, large‐grid, and acid‐etched surface. Purpose This prospective, longitudinal study evaluated clinical radiographic (SLA) surface implants for 5 years. Materials Methods Sixty were placed in sixty patients partially edentulous maxillae or mandibles. The permanent prostheses inserted 2–4 months after placement. Clinical examinations performed at...
The present research aimed to elucidate a convenient, safe and economic approach induce the growth of endogenous bone tissue regeneration. S-UNL-E was prepared using reverse-phase evaporation, scutellarin encapsulation subsequently compared. Meanwhile, optimal preparation scheme developed an orthogonal method, particle size determined laser light scattering. In osteoblasts cultured in vitro, methyl thiazolyl tetrazolium (MTT), alkaline phosphatase (ALP) staining alizarin red were used detect...
BACKGROUND This study evaluated the clinical efficacy of polylactic acid (PLA) membranes in guiding bone regeneration anterior maxillary implants. MATERIAL AND METHODS Forty-eight participants with tooth loss requiring implantation guided were recruited and randomly divided into 2 groups (n=24): PLA membrane (experimental) Bio-Gide (control) group. Wound healing was observed at 1 week month postoperatively. Cone beam CT performed immediately 6 36 months Soft-tissue parameters measured 18...
Abstract Immediate oral implant placement is a widely accepted technique, known for its efficacy in reducing treatment duration, surgical visits, and overall healing time. One of the primary challenges associated with immediate attainment initial stability. The inevitable loss bone soft tissue after extraction poses risk to osseointegration both vertical horizontal dimensions. Guided regeneration/guided regeneration (GTR/GBR) well‐established method periodontal regeneration. However, current...
Pyroptosis, an inflammatory cell death, plays a pivotal role in activating response, reversing immunosuppression and enhancing anti-tumor immunity. However, challenges remain regarding how to induce pyroptosis efficiently precisely tumor cells amplify immunotherapy. Herein, pH-responsive polydopamine (PDA) nanocluster, perfluorocarbon (PFC)@octo-arginine (R
Autophagy can affect the invasion and metastasis of carcinoma. Our previous study has shown that epithelial-mesenchymal transition in salivary adenoid cystic carcinoma (SACC) be promoted by metabolic reprogramming free fatty acids (FFAs). However, effect FFA metabolism on autophagy SACC remains unknown. In this study, we showed overexpression paired related homeobox 1 (PRRX1) reduced number autophagosomes decreased expression LC3 Beclin-1 patients SACC-83 cells vitro. Moreover,...
Guided bone regeneration (GBR) technique is most commonly used to treat alveolar defect. Polylactic acid (PLA) attracts much attention utilize as a GBR membrane because it has relatively high mechanical strength and biodegradability. However, randomized controlled trials of PLA in animals were rare. The aim this work observe the efficacy polylactic guiding Beagle canine defect restoration compare with collagen membrane, providing an experimental basis for further clinical use membrane. tests...
To investigate the effect of Porphyromonas gingivalis (Pg) with different fimA genotypes on vascular cell adhesion molecule-1 (VCAM-1) and intercellular (ICAM-1) production by human umbilical vein endothelial cells (HUVEC).In present study, PgATCC33277 (type I genotype), WCSP 115 II W83 IV Escherichia coli-lipopolysaccharide (Ec-LPS) were designed as experimental group 1, 2, 3, positive control group, respectively, to stimulate HUVEC, un-stimulated HUVEC analyzed negative group. The three...