A5100373110- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac Health and Mental Health
- Infective Endocarditis Diagnosis and Management
- Epilepsy research and treatment
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Neuroscience and Neuropharmacology Research
- Heart Rate Variability and Autonomic Control
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Growth Hormone and Insulin-like Growth Factors
- Cardiac Arrhythmias and Treatments
- Pharmacological Effects and Toxicity Studies
- Viral Infections and Immunology Research
- Pituitary Gland Disorders and Treatments
- Vitamin K Research Studies
- Cardiovascular Issues in Pregnancy
- Alcohol Consumption and Health Effects
- Sexual function and dysfunction studies
- Coronary Artery Anomalies
- Venous Thromboembolism Diagnosis and Management
- Medical Imaging and Pathology Studies
- Enhanced Recovery After Surgery
- Receptor Mechanisms and Signaling
West China Hospital of Sichuan University
2011-2024
Fujian Medical University
2024
Sichuan University
2011-2024
Zhejiang University
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2023
Peking Union Medical College Hospital
2023
West China Second University Hospital of Sichuan University
2023
Shandong Provincial Hospital
2023
Shandong First Medical University
2023
Optimal Solutions (United States)
2022
Tranexamic acid is recommended for reducing blood loss and transfusion in cardiac surgery. However, it remains unknown whether a high dose of tranexamic provides better blood-sparing effect than low without increasing the risk thrombotic complications or seizures surgery.To compare efficacy adverse events high-dose vs low-dose patients undergoing surgery with cardiopulmonary bypass.Multicenter, double-blind, randomized clinical trial among adult bypass. The study enrolled 3079 at 4 hospitals...
The aim of this paper is to observe the change mitochondrial aldehyde dehydrogenase 2 (ALDH2) when diabetes mellitus (DM) rat heart was subjected ischemia/reperfusion (I/R) intervention and analyze its underlying mechanisms. DM hearts were 30 min regional ischemia 120 reperfusion in vitro pretreated with ALDH2 activator ethanol (EtOH); cardiomyocyte high glucose (HG) condition Alda-1. In control I/R group, myocardial tissue structure collapse appeared. Compared left ventricular parameters,...
Abstract Objective Epilepsy is associated with progressive cortical atrophy exceeding normal aging. We aimed to explore longitudinal alterations in patients temporal lobe epilepsy (TLE) and distinct surgery outcomes. Methods obtained T1‐weighted MRI data a well‐designed cohort, including 53 operative TLE patients, 23 nonoperative healthy controls. According seizure outcomes at 24 months after surgery, were divided into seizure‐free (SF) nonseizure‐free (NSF) group. Operative scanned before...
This study aimed to investigate the impact of timing interval start AED withdraw (TIW) after surgery on seizure outcome in non-neoplastic drug resistant epilepsy (DRE). TIW were divided into three groups (respectively,<1 year, 1-<2 years, and ≥2 years). The at different time points starting withdrawal compared among groups. Other factors that related recurrence included multiple analysis predictors seizure-free. Altogether, 205 patients involved study. 102 individuals (50%) had 127 (62%)...
This study was aimed to investigate the clinical relevance between glycoprotein Ia (GPIA) rs1126643C/T polymorphism and outcome of coronary artery disease after bypass graft (CABG) surgery explore involved potential mechanisms.
Glioblastoma multiforme (GBM; grade IV glioma) is the most malignant type of primary brain tumor and characterized by rapid proliferation invasive growth. Intermedin (IMD) an endogenous peptide belonging to calcitonin gene-related family has been reported play important role in cell survival invasiveness several types cancers. In this study, we found that expression level IMD was positively related malignancy gliomas. The highest GBM, indicating may glioma malignancy. increased ability cells...
Background: The choice between bioprosthetic and mechanical valves for aortic valve replacement (AVR) mitral (MVR) among patients aged 50–70 years is controversial. We compared the long-term outcomes of using or to provide clinical evidence selection. Methods: From 2002 2007, who underwent isolated AVR MVR at Fuwai Hospital were enrolled. After inverse probability-weighted (IPW) propensity balancing, we evaluated mortality, stroke, bleeding events receiving biological prostheses AVR....
Observation of pituitary neuroendocrine tumors with streaky sign on MRI, analysis their features imaging and further investigation the relationship between direction streak optimal tumor expansion.
Abstract Objective Dystonic posturing (DP) is a common semiology in temporal lobe epilepsy (TLE). We aimed to explore cerebellar gradient alterations functional connectivity TLE patients with and without DP. Methods Resting‐state MRI data were obtained 60 32 matched healthy controls. Patients further divided into two groups: DP (TLE + DP, 31 patients) (TLP‐DP, 29 patients). explored the cerebellum based on cerebellar–cerebral combined independent component analysis evaluate integration...
Journal Article A rare case of haemorrhagic left atrial bouncing ball myxoma Get access Heng Zhang, Zhang Department Cardiovascular Surgery, First Affiliated Hospital, School Medicine, Zhejiang University, 79 Qingchun Rd., Shangcheng District, Hangzhou 310058, China https://orcid.org/0000-0001-8866-0932 Search for other works by this author on: Oxford Academic PubMed Google Scholar Xuelian Ao, Ao Ultrasound, Hangzhou, Haige Zhao Corresponding author. Email: haigezhao@zju.edu.cn...
Myxofibrosarcoma is a rare type of highly malignant sarcoma which easily occur lung metastasis. We report metastatic myxofibrosarcoma generated from the upper and middle lobe lung, invading right superior pulmonary vein, extending to left atrium. A single imaging examination may lead misdiagnosis, so combination computed tomography imaging, magnetic resonance as well positron emission tomographic scan are necessary for perioperative diagnosis surgical planning.
Deep venous thrombosis (DVT) is one of the most common complications after total joint replacement, which also concerned problems for clinicians. Domestic research data shows that incidence DVT in patients without thrombotic prophylaxis replacement surgery are 20.6%-40.0%. The occurrence mechanism explained by Virchow theory, blood stasis, vessel wall damage and coagulation state. diagnostic rate not satisfactory. diagnosis symptomatic depends mainly on clinical symptoms auxiliary...