A5020632877- Helminth infection and control
- Glycosylation and Glycoproteins Research
- Parasite Biology and Host Interactions
- Coccidia and coccidiosis research
- Parasites and Host Interactions
- Carbohydrate Chemistry and Synthesis
- Parasitic Infections and Diagnostics
- Infectious Diseases and Mycology
- Microbial Metabolites in Food Biotechnology
- Mycobacterium research and diagnosis
- Cardiovascular Disease and Adiposity
- Tourism, Volunteerism, and Development
- SARS-CoV-2 and COVID-19 Research
- Immunotherapy and Immune Responses
- Biotin and Related Studies
- Mollusks and Parasites Studies
- Ultrasound in Clinical Applications
- Boron Compounds in Chemistry
- Peptidase Inhibition and Analysis
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Parasitic infections in humans and animals
- Cardiovascular Effects of Exercise
- Veterinary medicine and infectious diseases
- Cardiac Imaging and Diagnostics
Universidade de Santiago de Compostela
2021
University College Dublin
2014-2020
Complexo Hospitalario Universitario A Coruña
2009
AimsAlthough peak may have higher sensitivity than post-treadmill exercise echocardiography (EE) for the detection of coronary artery disease (CAD), its prognostic value remains unknown. We sought to assess relative values and post-EE predicting outcome in patients with known/suspected CAD.
Recently, the prevalence of Fasciola hepatica in some areas has increased considerably and availability a vaccine to protect livestock from infection would represent major advance tools available for controlling this disease. To date, most vaccine-target discovery research on parasite concentrated proteomic transcriptomic approaches whereas little work been carried out glycosylation. As F. tegument (Teg) may contain glycans potentially relevant development Newly Excysted Juvenile (NEJ) is...
The parasitic helminth Fasciola hepatica (liver fluke) causes economic loss to the livestock industry globally and also zoonotic disease. New control strategies such as vaccines are urgently needed, due rise of drug resistance in parasite populations. Vaccine development requires a comprehensive understanding immunological events during infection. Previous vivo studies by our group have investigated global differentially expressed genes (DEGs) ovine peripheral blood mononuclear cells (PBMC)...
Abstract Although the rumen fluke, Calicophoron daubneyi is now very common and widespread throughout Western Europe, reports of clinical cases are still rare. This study explores epidemiological background to a severe fluke outbreak in 6-month-old heifers on dairy farm Ireland. Sequence analysis cytochrome oxidase subunit 1 (Cox1) gene metacercariae pasture failed identify predominant, possibly pathogenic subtypes. However, estimates metacercarial load indicated that animals were exposed...
Abstract To date, there are no recent studies identifying the prevalence of parasites human and veterinary importance in dogs cats Ireland. The interaction between pets wildlife species environment is an important source parasite exposure to canids felines, one likely be heightened stray animal population. This study aimed establish endoparasites unowned County Dublin, Feces from ( n = 627) 289) entering a rehoming centre were collected immediately after defecation. main parasitic agents...
Abstract Glycoproteins secreted by helminth parasites are immunogenic and represent appealing components of vaccine preparations. Our poor knowledge the pathways that mediate protein glycosylation in parasitic flatworms hinders our understanding how proteins synthesised modified, ability to target these for parasite control. Here we provide first detailed description genes associated with a flatworm, focusing on genome liver fluke ( Fasciola hepatica ), which is globally important trematode...
SUMMARY Fasciola hepatica is a parasitic trematode that causes serious losses to livestock producers, and also zoonotic disease. The limitations of chemotherapy for the control fasciolosis have led significant interest in development vaccines protect cattle sheep from infection. However, relatively few studies concentrated on mechanisms invasion gut by newly excysted juvenile liver flukes (NEJ) host response triggered this event. aim work was develop an vitro model study NEJ, while reducing...
Fasciola hepatica has both zoonotic importance and high economic impact in livestock worldwide. After ingestion by the definitive host, Newly Excysted Juveniles (NEJ) penetrate intestine before reaching peritoneal cavity. The role of some NEJ-derived proteins invasion been documented, but NEJ glycans or lectin-binding receptors during initial infection gut is still unknown. To address these questions, migration through rat was recorded at 30 min intervals up to 150 two ex vivo methods....
Fasciola hepatica causes economically important disease in livestock worldwide. The relevance of this parasitic infection extends beyond its direct consequences due to immunoregulatory properties.Given the importance T helper 1 (Th1) immune response controlling infections with Mycobacterium avium subspecies paratuberculosis (MAP) cattle, we aimed establish immunological that co-infection F. might have on course Johne's (JD).This study compared vitro bovine cells MAP or exposure antigens...
Abstract Introduction The first case of COVID-19 infection was described in Wuhan, China, December 20191. Shortly after, cases limited human-to-human transmission were reported other countries, which made the WHO declare outbreak a Public Health Emergency International Concern (ESPII) on January 30, 20202. Recent studies suggest that treatment with angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARAB) during acute has no effect mortality3, but it is...