A. Guillaume

ORCID: 0000-0001-8890-8459
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About
Contact & Profiles
Research Areas
  • Archaeology and Historical Studies
  • Visual perception and processing mechanisms
  • Biblical Studies and Interpretation
  • Historical and Linguistic Studies
  • Vestibular and auditory disorders
  • Islamic Studies and History
  • Neural dynamics and brain function
  • Motor Control and Adaptation
  • Ophthalmology and Eye Disorders
  • Glaucoma and retinal disorders
  • African history and culture analysis
  • Tactile and Sensory Interactions
  • Diabetes Management and Education
  • EEG and Brain-Computer Interfaces
  • Hemispheric Asymmetry in Neuroscience
  • Gaze Tracking and Assistive Technology
  • Diabetes Management and Research
  • Neuroscience and Neuropharmacology Research
  • Neural and Behavioral Psychology Studies
  • Spatial Neglect and Hemispheric Dysfunction
  • Neuroscience of respiration and sleep
  • Retinal Development and Disorders
  • Ancient Near East History
  • Foot and Ankle Surgery
  • Advanced Memory and Neural Computing

Université Paris Cité
2016-2022

Laboratoire Vision Action Cognition
2019-2022

Hôpital Pellegrin
2016-2020

Laboratoire de Neurosciences Cognitives
1998-2018

Centre National de la Recherche Scientifique
2006-2018

Aix-Marseille Université
2010-2018

New York University
2014-2018

Centre Hospitalier Universitaire de Bordeaux
2016-2017

Hôpitaux Universitaires de Strasbourg
2014-2016

Institut de Recherche pour le Développement
2016

Physical therapy without anesthesia or plaster casts was used to treat 338 cases of clubfoot (CF). Our technique is based on progressive sequential manipulations at birth. We first reduce the varus and later equinus component CF. The gentle stretches in this are complemented by active physiotherapy stimulating muscles, then a simple splint suited foot fix its degree realignment. When alone, achieves 77% good fair results. In resistant cases, complementary surgery used. obtained 96%

10.1097/01241398-199003000-00010 article EN Journal of Pediatric Orthopaedics 1990-03-01

(1946). The Ḫabiru, the Hebrews, and Arabs. Palestine Exploration Quarterly: Vol. 78, No. 2, pp. 64-85.

10.1179/peq.1946.78.2.64 article EN Palestine Exploration Quarterly 1946-10-01

Abstract Nanosized drug crystals have been reported with enhanced apparent solubility, bioavailability, and therapeutic efficacy compared to microcrystal materials, which are not suitable for parenteral administration. However, nanocrystal design development by bottom‐up approaches challenging, especially considering the non‐standardized process parameters in injection step. This work aims present a systematic step‐by‐step approach through Quality‐by‐Design (QbD) Design of Experiments (DoE)...

10.1002/smll.202306054 article EN cc-by Small 2024-02-01

Studying the transfer of visuomotor adaptation from a given effector (e.g., eye) to another hand) allows us question whether sensorimotor processes influenced by are common both control systems and thus address level where takes place. Previous studies have shown only very weak amplitude reactive saccades--i.e., produced automatically in response sudden appearance visual targets--to hand pointing movements. Here we compared movements recorded before after either or voluntary saccades,...

10.1152/jn.00293.2007 article EN Journal of Neurophysiology 2007-06-07

Sensorimotor adaptation restores and maintains the accuracy of goal-directed movements. It remains unclear whether these adaptive mechanisms modify actions by controlling peripheral premotor stages that send commands to effectors and/or earlier processing involved in registration target location. Here, we studied effect saccadic eye movements, a well-established model sensorimotor adaptation, an antisaccade task. This task introduces clear spatial dissociation between actual direction...

10.1113/jphysiol.2008.159459 article EN The Journal of Physiology 2008-11-18

The interhemispheric transfer of information is a fundamental process in the human brain. When visual stimulus appears eccentrically one visual-hemifield, it will first activate contralateral hemisphere but also ipsilateral with slight delay due to transfer. This believed be faster from right left right-handers. Such an asymmetry considered as relevant fact context lateralization We show here using current source density (CSD) analyses visually evoked potential (VEP) that, right-handers and,...

10.3389/fnins.2018.00072 article EN cc-by Frontiers in Neuroscience 2018-02-16

The aim of this study was to determine, in a population with metastatic breast cancer treated bevacizumab therapy, the incidence wound dehiscence after placement an implantable venous access device (VAD) and risk catheter thrombosis. This enrolled all VADs placed by 14 anesthetists between 1 January 2007 31 December 2009: 273 patients therapy 4196 not therapy. In group, 13 cases occurred 12 requiring removal VAD (4.76%). All when initiated less than 7 days placement. Bevacizumab 150 (13 150:...

10.1097/cad.0b013e328349c7bb article EN Anti-Cancer Drugs 2011-10-04

Treatment of clubfoot requires a detailed knowledge the underlying pathophysiology. We explain concept that led us to propose our technique called functional treatment. It is centered on progressive manipulations correct different deformations step-by-step. These are performed according four stages; treatment completed by light splints, which used between sessions. As this does not give complete reduction foot, complementary surgical correction becomes necessary therapy. Surgical follows...

10.1097/01202412-199403020-00006 article EN Journal of Pediatric Orthopaedics B 1994-01-01

Behavioral studies have suggested that the brain uses a visual estimate of hand to plan reaching movements toward targets and somatosensory inputs in case targets. However, neural correlates for distinct coding according sensory modality target not yet been identified. Here we tested twofold hypothesis input from is facilitated inhibited, respectively, when planning (unseen fingers) or The weight was assessed by measuring amplitude evoked potential (SEP) resulting vibration finger during...

10.1152/jn.00857.2013 article EN Journal of Neurophysiology 2014-08-14

Pélisson, Denis, Laurent Goffart, and Alain Guillaume. Contribution of the rostral fastigial nucleus to control orienting gaze shifts in head-unrestrained cat. J. Neurophysiol. 80: 1180–1196, 1998. The implication caudal part (cFN) saccadic visual axis is now well established. In contrast a possible involvement (rFN) remains unknown. current study we investigated cat contribution rFN visually triggered by measuring deficits after unilateral muscimol injection rFN. A typical dysmetria was...

10.1152/jn.1998.80.3.1180 article EN Journal of Neurophysiology 1998-09-01

Goffart, Laurent, Denis Pélisson, and Alain Guillaume. Orienting gaze shifts during muscimol inactivation of caudalfastigial nucleus in the cat. II. Dynamics eye-head coupling. J. Neurophysiol. 79: 1959–1976, 1998. We have shown companion paper that injection caudal part fastigial (cFN) consistently leads to dysmetria visually triggered depends on movement direction. Based observations a constant error misdirected movements toward inactivated side, we proposed cFN contributes specification...

10.1152/jn.1998.79.4.1959 article EN Journal of Neurophysiology 1998-04-01

Saccade adaptation is the learning process that ensures vision and saccades remain calibrated. The central nervous system network involved in these adaptive processes remains unclear because of difficulties isolating from correlated visual motor processes. Here we imaged human brain during a novel saccade paradigm allowed us to isolate neural signals independent changes amplitude corrective usually with adaptation. We show activation ipsiversive cerebellar vermis track are not driven by thus...

10.1152/jn.00392.2018 article EN Journal of Neurophysiology 2018-09-12

Several studies have suggested that the pattern of neuronal activity in superior colliculus (SC) interacts with well-known topographical coding saccades (motor map). To further describe this interaction, we recorded gaze evoked by electrical microstimulation SC deeper layers head-unrestrained cat and systematically varied collicular locus (25 sites) parameters (intensity, frequency) stimulation. Long stimulation trains were used to avoid saccade truncation. We found direction amplitude...

10.1046/j.0953-816x.2001.01744.x article EN European Journal of Neuroscience 2001-10-01

Abstract Saccadic inhibition refers to the strong temporary decrease in saccadic initiation observed when a visual distractor appears shortly after onset of target. Here, gain better understanding this phenomenon, we assessed whether saccade amplitude changes could accompany these modulations latency distributions. As previous studies on system using backward masking—a protocol which mask target—showed increases and changes, suspected that be condition would inhibition. We show here masking...

10.1167/12.6.5 article EN cc-by-nc-nd Journal of Vision 2012-06-01
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