- Glycosylation and Glycoproteins Research
- Cytokine Signaling Pathways and Interactions
- Viral-associated cancers and disorders
- Adenosine and Purinergic Signaling
- Immune Cell Function and Interaction
- Gut microbiota and health
- Oral microbiology and periodontitis research
- Epigenetics and DNA Methylation
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Genital Health and Disease
- Cancer-related gene regulation
- Cell death mechanisms and regulation
- Head and Neck Cancer Studies
- Diphtheria, Corynebacterium, and Tetanus
- Cancer Cells and Metastasis
- Oral Health Pathology and Treatment
Presidency University
2021-2025
Presidency University
2024
Infection with specific pathogens and alterations in tissue commensal microbial composition are intricately associated the development of many human cancers. Likewise, dysbiosis oral microbiome was also shown to play critical role initiation as well progression cancer. However, there no reports portraying changes community patients Indian subcontinent, which has highest incidence cancer per year, globally. To establish association bacterial squamous cell carcinoma (OSCC) among population,...
Epstein-Barr virus (EBV) contributes to ~1% of all human cancers including several B-cell neoplasms. A characteristic feature EBV life cycle is its ability transform metabolically quiescent B-lymphocytes into hyperproliferating blasts with the establishment viral latency, while intermittent lytic induction necessary for production progeny virus. Our RNA-Seq analyses both latently infected naïve and transformed upon replication indicate a contrasting expression pattern membrane-associated...
Apart from other risk factors, chronic inflammation is also associated with the onset of Prostate Cancer (PCa), wherein pathogen infection and tissue microbiome dysbiosis are known to play a major role in both inflammatory response cancer development. However, except for few studies, link between microbes PCa remained poorly understood. To explore potential signature Indian patients, we investigated differential compositions commensal bacteria among patients benign prostatic hyperplasia...
Abstract c-FLIP (cellular FLICE-Like Inhibitor of Apoptotic protein) which belongs to the negative regulators death receptor pathway, control apoptosis in a number cancers. literatures suggest that its overexpression facilitate cancer progression and also helps drug resistance. However, there is very few data available show how it metastasis. Moreover, cFLIP regulated during into advanced stage mechanism action on tumor cell migration invasion yet be known. Our TCGA analysis has shown...
Abstract Apart from other risk factors, chronic inflammation is also associated with the onset of Prostate Cancer (PCa), wherein pathogen infection and tissue microbiome dysbiosis are known to play a major role for both inflammatory response cancer development. However, except few studies, link between microbes PCa remained poorly understood. To explore potential signature in Indian patients, we investigated differential compositions commensal bacteria among patients benign prostatic...
Abstract Epstein-Barr virus (EBV) contributes to ∼1% of all human cancers including several B-cell neoplasms. A characteristic feature EBV life cycle is its ability transform metabolically quiescent B-lymphocytes into hyperproliferating blasts with the establishment viral latency, while intermittent lytic induction necessary for production progeny virus. Our RNA-Seq analyses both latently infected naïve and transformed upon replication indicate a contrasting expression pattern...