- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Properties of Aromatic Compounds
- Immunodeficiency and Autoimmune Disorders
- Organic Chemistry Cycloaddition Reactions
- Fullerene Chemistry and Applications
- Advanced Graph Theory Research
- Crystallography and molecular interactions
- Fluid Dynamics and Vibration Analysis
- Organic Electronics and Photovoltaics
- Immune cells in cancer
- Perovskite Materials and Applications
- HVDC Systems and Fault Protection
- Advanced Memory and Neural Computing
- Chronic Lymphocytic Leukemia Research
- Graph Labeling and Dimension Problems
- Blood disorders and treatments
- Graphene research and applications
- Aerodynamics and Fluid Dynamics Research
- Magnetism in coordination complexes
- Nanoplatforms for cancer theranostics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- graph theory and CDMA systems
- Supramolecular Self-Assembly in Materials
- Ferrocene Chemistry and Applications
Nanyang Technological University
2022-2024
Nanjing Forestry University
2024
Beijing University of Technology
2023
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2023
Unité Matériaux et Transformations
2023
State Key Laboratory of Chemical Engineering
2023
Tianjin University
2023
China Special Equipment Inspection and Research Institute
2022
National Taiwan Ocean University
2021
Shanghai Jiao Tong University
2014-2019
X-linked agammaglobulinemia (XLA) is a humoral primary immunodeficiency. XLA patients typically present with very low numbers of peripheral B cells and profound deficiency all immunoglobulin isotypes. Most carry mutations in Bruton tyrosine kinase (BTK) gene. The genetic background clinical features 174 Chinese were investigated. relationship between specific BTK gene severity manifestations was also examined. Mutations graded from mild to severe based on structural functional prediction...
A fully conjugated azacorannulene dimer with a large π-surface (76π system) was successfully synthesized from bifunctional polycyclic aromatic azomethine ylide. This molecule represents an example of diaza[80]fullerene (C78N2) fragment bearing two internal nitrogen atoms. X-ray crystallography analysis shows its boat-shaped structure terminal azacorannulenes bent in the same direction. The molecular shape leads to unique selective association dumbbell-shaped C60 (C120) over through...
X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed clinical and molecular features 20 Chinese patients diagnosed followed up hospitals affiliated to Shanghai Jiao Tong University School Medicine 1999 2013. The median onset age these was 8.5 months (range: days–21 months). Half them had positive family histories, with a shorter diagnosis lag. most common symptoms...
Abstract Sulfur‐embedded polycyclic aromatic compounds have been used as building blocks for numerous organic semiconductors over the past few decades. While success is based on thiophene‐containing compounds, that contain thiepine, a sulfur‐containing seven‐membered‐ring arene, has less well investigated. Here we report synthesis and properties of π‐extended pyrrole‐fused heteropine such thiepine oxepine. A exhibited “pitched π‐stacking” structure in crystal, high charge carrier mobility up...
Photo-induced cancer therapies, mainly including photothermal therapy (PTT) and photodynamic (PDT), have attracted numerous attentions owing to the high selectivity, convenience, few side effects. However, single PTT usually requires laser power density, PDT needs a photosensitizer dosage. Herein, kind of composite nanocarrier based on clay (laponite)-polypyrrole (LP) nanodisks was synthesized via in situ polymerization pyrrole interlayer space laponite. LP were then coated with...
Two nitrogen-doped positively curved aromatic molecules bearing doubly fused pentagonal rings were synthesized and characterized. Crystallographic analysis confirms the formation of a bowl-shaped structure, which is induced by fusion adjacent pentagons to rigid planes. Both compounds demonstrate good photoluminescence. These electron-rich can associate with C
Real-time simulation of modular multilevel converter (MMC)-based HVDC is one the most important and difficult technologies in area power electronics research. This paper presents a methodology for hardware loop (HIL) CPU/FPGA-based real-time one-terminal MMC up to 468 levels using detailed equivalent model, system based on full-scale physical control system, including actual sub module boards. The testing subject accompanying are same symmetric structure, without expensive third part HIL...
Abstract The functionalization of small aromatic heterocycles is a straight and efficient method to access large polycyclic conjugated molecules. However, due its unique reactivity, the derivatization acridone usually gives product in angular shape difficult obtain linear ones. Here we report direct generate linearly fused derivatives containing cyclobutadienoid via palladium‐catalyzed arene‐(oxa)norbornene annulation followed by dehydrated aromatization. experimental characterizations...
The functionalization of N-heterotriangulenes has been extensively investigated for their potentials as optoelectronic materials. However, study on the influence molecular geometry property N-heterotriangulene is still rare....
A nitrogen-doped heptagon-centered molecular bowl that can be viewed as a fragment mapped from fullerene violating the isolated pentagon rule was synthesized and characterized.
Polycyclic aromatic diradical(oid) molecules are attracting significant attention because of their unique electronic and magnetic properties as well applications functional materials. While bearing five‐membered rings have been extensively investigated, those seven‐membered relatively fewer. Herein, we report the synthesis azapentabenzodihomocorannulene dication diradical molecules. The was achieved through a mechanochemical C(sp2)–H/C(sp3)–H coupling in presence sodium key reaction....
Polycyclic aromatic diradical(oid) molecules are attracting significant attention because of their unique electronic and magnetic properties as well applications functional materials. While bearing five‐membered rings have been extensively investigated, those seven‐membered relatively fewer. Herein, we report the synthesis azapentabenzodihomocorannulene dication diradical molecules. The was achieved through a mechanochemical C(sp2)–H/C(sp3)–H coupling in presence sodium key reaction....
Abstract Sulfur‐embedded polycyclic aromatic compounds have been used as building blocks for numerous organic semiconductors over the past few decades. While success is based on thiophene‐containing compounds, that contain thiepine, a sulfur‐containing seven‐membered‐ring arene, has less well investigated. Here we report synthesis and properties of π‐extended pyrrole‐fused heteropine such thiepine oxepine. A exhibited “pitched π‐stacking” structure in crystal, high charge carrier mobility up...