A5103633202- Influenza Virus Research Studies
- Mercury impact and mitigation studies
- Environmental Toxicology and Ecotoxicology
- Respiratory viral infections research
- Heavy metals in environment
- Retinal Development and Disorders
- Neuroscience and Neuropharmacology Research
- Bacteriophages and microbial interactions
- Tryptophan and brain disorders
- Inhalation and Respiratory Drug Delivery
- Enzyme Production and Characterization
- Virology and Viral Diseases
- Photoreceptor and optogenetics research
- Advanced Nanomaterials in Catalysis
- Ocular Diseases and Behçet’s Syndrome
- Nanoparticles: synthesis and applications
- Biofuel production and bioconversion
- Advanced Chemical Sensor Technologies
- Viral Infections and Vectors
- Protein purification and stability
- Studies on Chitinases and Chitosanases
- Retinal Diseases and Treatments
- Mass Spectrometry Techniques and Applications
- Stress Responses and Cortisol
Aalto University
2025
Australian Nuclear Science and Technology Organisation
2014-2024
The University of Sydney
2011-2018
Often, the value of whole biomass from fermentation processes is not exploited, as commercial interests are focused on main product that typically either accumulated within cells or secreted into medium. One underutilized fraction yeast cell wall contains valuable polysaccharides, such chitin, known for its biocompatibility and biodegradability, which thought properties in diverse industries. Therefore, valorization waste to coproduce chitin could significantly improve overall profitability...
This study used the radioisotopes (109)Cd and (65)Zn to explore uptake, retention organ distribution of these nonessential essential metals from solution by freshwater decapod crustacean Macrobrachium australiense. Three treatments consisting cadmium alone, zinc a mixture were determine differences in uptake efflux rates each metal individually over three-week period, followed depuration for 2 weeks metal-free water using live-animal gamma-spectrometry. Following exposure, prawns...
Purpose: Macular Telangiectasia Type 2 (MacTel-2) is a retinal disease that can cause loss of central vision.To gain better understanding the aetiology and pathogenesis MacTel-2, we investigated antigens which prompt generation autoantibodies in sera MacTel-2 patients. Methods:We screened for presence 45 collected from patients 68 healthy controls by Western Blot.We then isolated identified three proteins are putative targets most frequently detected patients, using chromatographic...
The uptake, depuration, and organ distribution of the radioisotope 109Cd were used to explore internal kinetics this nonessential metal following accumulation from waterborne cadmium by freshwater decapod crustacean Macrobrachium australiense. Short- (6 h) long-term (7 14 days) exposures in solutions 0.56 μg Cd/L followed depuration metal- isotope-free water for up 21 days. anatomical radionuclide was visualized using autoradiography at predefined time points. gills did not become saturated...
Schizophrenia is thought to arise due a complex interaction between genetic and environmental factors during early neurodevelopment. We have recently shown that partial deletion of the schizophrenia susceptibility gene neuregulin 1 (Nrg1) adolescent stress interact disturb sensorimotor gating, neuroendocrine activity dendritic morphology in mice. Both Nrg1 may converging effects upon N-methyl-D-aspartate receptors (NMDARs) which are implicated pathogenesis schizophrenia, gating spine...
Parainfluenza viruses (PIVs) are one of the most common causes respiratory tract infections in children and can be life-threatening when airway becomes obstructed. Infection results a spectrum disease symptoms that makes diagnosis difficult. A new proteotyping approach employing high-resolution mass spectrometry is shown to able distinguish human serotypes PIV from perspective all surface internal viral proteins. The detection signature peptides, conserved sequence unique mass, within...
A proteotyping approach which employs high resolution mass spectrometry is shown to be able differentiate all nine neuraminidase subtypes of type influenza viruses that infect both humans and animals. Conserved sequences among tryptic peptides were identified through alignments across N1–N9 human animal hosts. Those unique in represent signature which, when detected the spectra an or whole virus digest, enable strains subtyped with confidence. The ability distinguish N1 derived from H5N1...