Tuomas Mansikkala

ORCID: 0000-0001-8920-7291
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About
Contact & Profiles
Research Areas
  • X-ray Spectroscopy and Fluorescence Analysis
  • Advanced X-ray Imaging Techniques
  • Magnesium Oxide Properties and Applications
  • Nuclear Physics and Applications
  • Biochemical and biochemical processes
  • X-ray Diffraction in Crystallography
  • Concrete and Cement Materials Research
  • Enzyme Structure and Function
  • Pluripotent Stem Cells Research
  • Advanced MRI Techniques and Applications
  • Plant biochemistry and biosynthesis
  • 3D Printing in Biomedical Research
  • Plant pathogens and resistance mechanisms
  • Tissue Engineering and Regenerative Medicine

University of Oulu
2020-2024

Biocenter Finland
2023

Tampere University
2019

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have the potential to serve as a model for human cardiomyocytes. However, hiPSC-CMs are still considered immature. CMs differentiated from hiPSCs more resemble fetal than adult Putative factors enhancing maturation include in vitro culture duration, surface topography, and mechanical, chemical, electrical stimulation. Stem traditionally cultured on glass surfaces coated with extracellular matrix derivatives such gelatin....

10.3390/ma12111805 article EN Materials 2019-06-03

Lignans are bioactive compounds that especially abundant in the Norway spruce (Picea abies L. Karst.) knotwood. By combining a variety of chromatographic, spectroscopic and imaging techniques, we were able to quantify, qualify localise easily extractable lignans xylem tissue. The knotwood samples contained 15 different according gas chromatography-mass spectrometry analysis. They comprised 16% dry weight 82% acetone extract. main found be hydroxymatairesinols HMR1 HMR2. Cryosectioned...

10.3390/molecules25132997 article EN cc-by Molecules 2020-06-30

A comparative study of normal human fibroblasts and Salla disease patients' reveals changes in the soft X-ray spectroscopic signatures cells. Synchrotron radiation imaging was performed for thin sections grid-grown

10.1039/d4ra05520a article EN cc-by RSC Advances 2024-01-01

Scanning transmission X-ray microscopy (STXM) in the soft range is well-suited to study ultrastructural features of mammalian tissues. Especially at carbon 1s edge, imaging contrast varies drastically across edge due rapid changes absorption cross-section functional groups present tissue samples enabling label-free spectromicroscopic studies. We STXM mouse kidney and liver especially concentrate on abnormalities genetically modified Slc17a5 mice. a promising technique storage diseases...

10.1016/j.elspec.2023.147368 article EN cc-by Journal of Electron Spectroscopy and Related Phenomena 2023-07-01
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