A5061178060- Magnetic and transport properties of perovskites and related materials
- Electronic and Structural Properties of Oxides
- Advanced Condensed Matter Physics
- Iron-based superconductors research
- Force Microscopy Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- Rare-earth and actinide compounds
- Biochemical and Molecular Research
- Integrated Circuits and Semiconductor Failure Analysis
- Glycosylation and Glycoproteins Research
- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Bacteriophages and microbial interactions
- Immune cells in cancer
- Advanced Materials Characterization Techniques
- Social Media in Health Education
- Semiconductor materials and devices
- Immune Cell Function and Interaction
- RNA and protein synthesis mechanisms
- Inflammasome and immune disorders
- Empathy and Medical Education
- Therapeutic Uses of Natural Elements
- Vehicle License Plate Recognition
- Bat Biology and Ecology Studies
- T-cell and B-cell Immunology
University of Southern California
2022-2023
Nirma University
2022
K J Somaiya Medical College
2021
University of Toronto
2021
Northwestern University
2010-2019
Rice University
2012
A simple approach for creating libraries of circularly permuted proteins is described that called PERMutation Using Transposase Engineering (PERMUTE). In PERMUTE, the transposase MuA used to randomly insert a minitransposon can function as protein expression vector into plasmid contains open reading frame (ORF) being permuted. library vectors express different variants ORF-encoded created by: (i) using bacteria select target acquire an integrated minitransposon; (ii) excising ensemble ORFs...
Ferromagnetism is usually considered to be incompatible with conventional superconductivity, as it destroys the singlet correlations responsible for pairing interaction. Superconductivity and ferromagnetism are known coexist in only a few bulk rare-earth materials. Here we report evidence their coexistence two-dimensional system: interface between two insulators, LaAlO(3) (LAO) SrTiO(3) (STO), system that has been studied intensively recently. Magnetoresistance, Hall, electric-field...
T cells and cancer utilize glycolysis for proliferation. The hexokinase (1-4) family of enzymes catalyze the first step glycolysis. Hexokinase 2 (HK2) is one most highly upregulated metabolic in both activated cells. HK2 required development and/or growth several models, but necessity not fully understood. clinical applicability inhibition may be significantly limited by any potential negative effects on Therefore, we investigated cell function. In order to identify additional therapeutic...
The normal state properties of the recently discovered ferropnictide superconductors might hold key to understanding their exotic superconductivity. Using point-contact spectroscopy we show that Andreev reflection between an epitaxial thin film $\mathrm{Ba}({\mathrm{Fe}}_{0.92}{\mathrm{Co}}_{0.08}{)}_{2}{\mathrm{As}}_{2}$ and a silver tip can be seen in up temperature $T\ensuremath{\sim}1.3{T}_{c}$, where ${T}_{c}$ is critical superconductor. far above understood only when superconducting...
We use a combination of global back-gating and local top-gating to define nanoscale devices in the two-dimensional electron gas at LaAlO3-SrTiO3 interface, demonstrating an efficient way for much finer spatial control over properties as compared alone. The show indications inhomogenous superconducting weak link. variation critical current with perpendicular magnetic field shows evidence oscillations, which hints Josephson coupling. zero bias resistance temperature is consistent short,...
Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement in which native protein termini become linked and new are created elsewhere backbone fission. However, it remains challenging to anticipate protein's functional tolerance permutation. Here, we describe transposons creating libraries of randomly circularly permuted proteins that minimize peptide additions at their termini, use transposase mutagenesis study the thermophilic adenylate kinase...
We present a study of the magnetic field tuned superconductor-to-insulator transition (SIT) in electron gas that forms at LaAlO$_3$/SrTiO$_3$ interface. find induces into weakly insulating state, as is observed for electrostatically SIT this Finite size scaling magnetoresistance yields critical exponent product $z\nu \simeq$ 7/3, indicating governed by quantum percolation effects. While such exponents have been reported previously high resistance films, they not low system like ours, with...
Point-contact spectroscopy is a powerful tool for probing superconductors. One of the most common observations in point-contact spectra on recently discovered ferropnictide superconductors large conductance asymmetry with respect to voltage across point-contact. In this paper we show that antisymmetric part spectrum between silver tip and an epitaxial thin film Ba(Fe$_{0.92}$Co$_{0.08}$)$_2$As$_2$ shows certain unique features. These features have interesting evolution increasing temperature...
Real time computer control is an essential feature of scanning probe microscopes, which have become tools for the characterization and investigation nanometer scale samples. Most commercial (and some open-source) data acquisition software uses digital signal processors (DSPs) to handle real processing control, adds expense complexity software. We describe here scan that a single card acquire data. The runs open-source Linux kernel, permits fast while maintaining responsive graphical user...
M. Mehta has no conflicts to disclose. A.O'Toole been an investigator, speaker or advisory board member for AbbVie, Amgen, Arcutis, Boehringer Ingelheim, BMS, Celgene, Dermira, Galderma, GSK, Eli Lilly, Incyte, Janssen, Leo Pharma, Merck, Novartis, Pfizer, Regeneron, Sanofi Genzyme, Sun UCB, Valeant/Bausch. Gooderham speaker, consultant Akros, Dermavant, Kyowa Kirin, Medimmune,
Non-contact scanning probe microscopy (SPM) has developed into a powerful technique to image many different properties of samples. The conventional method involves monitoring the amplitude, phase, or frequency cantilever oscillating at near its resonant as it is scanned across surface sample. For high Q factor cantilevers, preferred in order obtain reasonable scan times. This can be done by using phase-locked-loop (PLL). PLLs obtained commercial integrated circuits, but these do not have...
International Dermatology Outcome Measures (IDEOM) is a non-profit organization founded in 2013. It composed of researchers and stakeholders who work to develop evidenced-based outcome measures enhance research treatment recommendations dermatologic diseases.The 2021 IDEOM Virtual Annual Meeting occurred from November 19-20, 2021. Contributions were made by leaders the psoriasis, psoriatic arthritis, pediatric hidradenitis suppurativa, acne, vitiligo, actinic keratosis, alopecia areata,...
We demonstrate top-gate tunable Josephson junction like behavior in the two dimensional electron gas at LaAlO$_3$-SrTiO$_3$ interface. A combination of global back-gating and local top-gating is used to define junctions, providing an efficient way for much finer spatial control over properties interface, as compared alone. The variation critical currents zero bias resistances with temperature shows that junctions behave short, overdamped weak links. This technique could be important tool...
The conducting interface formed between the two insulators LaAlO3 (LAO) and SrTiO3 (STO) has been shown to have both magnetic superconducting properties. As was reported in an earlier publication, phases coexist simultaneously this system [1], with superconductivity being tuned by applied gate voltage. Here we report on transverse (Hall) magnetoresistance of as a function voltage, which tunes density carriers at interface. Not only is Hall resistance hysteretic, due order system, but also...
Psoriasis patients may seek information about the SARS-CoV-2 vaccine and their diagnosis from social media platforms. Analyses of interactions help guide dermatologists’ educational efforts during this pandemic.This study analyzed content sentiment online posts medication interaction between vaccines anti-psoriatic therapies among psoriasis patients.Publicly accessible Facebook Reddit groups regarding psoriatic arthritis were identified. Posts uploaded March 1, 2021, July 31, with...