A5083273735- Environmental and Ecological Studies
- Building Energy and Comfort Optimization
- Latin American Urban Studies
- Regional Development and Innovation
- Urbanism, Landscape, and Tourism Studies
- Pulmonary Hypertension Research and Treatments
- Architecture, Art, Education
- Solar Thermal and Photovoltaic Systems
- Water Resource Management and Quality
- Solar Energy Systems and Technologies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Educational methodologies and cognitive development
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Business, Innovation, and Economy
- Mediterranean and Iberian flora and fauna
- Environmental and sustainability education
- Urban Heat Island Mitigation
- Inhalation and Respiratory Drug Delivery
- Public Policy and Governance
- Environmental Education and Sustainability
- Historical Studies of Medieval Iberia
- Public Health and Environmental Issues
- Asthma and respiratory diseases
- Vascular Anomalies and Treatments
- Respiratory Support and Mechanisms
Consejo Nacional de Investigaciones Científicas y Técnicas
2013-2024
Universidad Nacional de La Plata
2010-2024
Instituto de Investigaciones y Políticas del Ambiente Construido (IIPAC)
2013-2023
Instituto de Desenvolvimento Sustentável Mamirauá
2020
Universidade Estadual de Ponta Grossa
2020
Centro Regional de Derechos Humanos y Justicia de Género, Corporación Humanas
2020
Hospital General Universitario De Valencia
1987-2019
Hospital de Manises
2017
Instituto de Salud Carlos III
2016
Universitat de València
2000-2014
We studied the effects of acute changes in partial pressure arterial carbon dioxide on diaphragmatic contractility and performance four normal men. To study we measured ability diaphragm to generate at a given level excitation by determining relation between electrical activity transdiaphragmatic during voluntary quasi-isometric inspiratory effort carried out different levels end-tidal dioxide. Our results show that was reduced with hypercapnia (when 7.5 per cent or higher), although...
<h3>Background</h3> Idiopathic pulmonary fibrosis (IPF) is characterised by the aberrant epithelial to mesenchymal transition (EMT) and myofibroblast accumulation. Sphingosine-1-phosphate (S1P) sphingosine kinase 1 (SPHK1) have been implicated in lung transition, but their role EMT expression patients with IPF unknown. <h3>Methods results</h3> S1P levels were measured serum (n=27) bronchoalveolar lavage (BAL; n=15) from controls (n=30 for n=15 BAL studies). SPHK1 was tissue (n=12) (n=15)....
Sildenafil improves the 6-min walking distance in patients with idiopathic pulmonary fibrosis (IPF) and right-sided ventricular systolic dysfunction.We analysed previously unexplored role of sildenafil on vasoconstriction remodelling arteries from IPF hypertension (PH) ex vivo Pulmonary 18 donors without lung disease, nine IPF, eight PH+IPF four PH were isolated to measure vasodilator anti-contractile effects isometric organ bath. Ventilation/perfusion was explored an animal model bleomycin...
Neutrophils and oxidative stress have been implicated in the pathogenesis of COPD. Severe, early-onset COPD is characterized by a rapid decline lung function at an early age; however, nothing known about neutrophil activation patients.The aim this study was to evaluate peripheral blood severe, patients versus healthy non-smokers effect N-acetyl-L-cysteine (NAC) on vitro.Neutrophils were isolated from 15 age-matched subjects stimulated with N-formyl-Met-Leu-Phe (fMLP) presence or absence NAC...
Inhaled corticosteroid (ICS) with long-acting beta-2 agonists is a well-documented combination therapy for chronic obstructive pulmonary disease (COPD) based on its additive anti-inflammatory properties. By contrast, the recommendation of ICS in muscarinic antagonist (LAMA) not evidence-based. In this study, neutrophils obtained from COPD patients were used to compare effects aclidinium bromide (a antagonist) corticosteroids and their potential effect. Human sputum blood isolated healthy...
Idiopathic Pulmonary arterial hypertension (IPAH) is characterized by the obstructive remodelling of pulmonary arteries, and a progressive elevation in pressure (PAP) with subsequent right-sided heart failure dead. Hypoxia induces expression peroxisome proliferator activated receptor γ coactivator-1 α (PGC-1 ) which regulates oxidative metabolism mitochondrial biogenesis. We have analysed PGC-1 , cytochrome C (CYTC), superoxide dismutase (SOD), total antioxidant status (TAS) activity...
Abstract Two asthmatic patients developed unilateral diaphragmatic paralysis from phrenic nerve injury, in one case following cervical chiropractic manipulation and the other after a motorcycle accident. Both presented with increased dyspnea orthopnea. Diagnosis, severity, level of lesion were established by neurophysiological methods, which are preferred to chest radiography ultrasonography. In spite only partial electrophysiological recovery nerve, both asymptomatic 1 year later. Muscle Nerve, 2007
Resumen La carga térmica para climatización de edificios (Q) estima la demanda energía en función un coeficiente global pérdidas (G) y los grados día (GD) refrigeración o calefacción. En general GD se calculan con las temperaturas medias publicadas por organismos oficiales. Sin embargo, ha demostrado que ciudad afecta al clima urbano generando variaciones térmicas debido a sus condiciones morfológicas materiales. Este trabajo analiza externas distintas zonas representativas (mosaicos urbanos...
El artículo expone los fundamentos, la metodología y resultados alcanzados en construcción de un Índice Pobreza Energética Multidimensional Ponderado (IPEMP), para provincia Buenos Aires, Argentina. IPEMP, propone método cálculo ponderación variables, a partir las cuales se evalúan niveles criticidad respecto características socioeconómicas, energéticas constructivas hogares estudio. Su aplicación sobre base datos censales situación pobreza energética, donde destaca partidos que conforman...
A partir de la década los 80, como resultado profunda crisis neoliberal posterior al golpe estado, periferia las ciudades argentinas, particularmente ciudad La Plata (Buenos Aires), ha cambiado su estructura socio espacial, quedando fragmentada y constituida manera informal. Dicha informalidad se debe a características asentamiento, sin ninguna regulación política institucional bajo leyes autogestión popular respecto acceso tierra vivienda. Este trabajo expone una metodología inserta en un...
Como producto de las últimas políticas neoliberales llevadas a cabo en el ámbito urbano, ciudades han crecido manera desigual, fragmentada y desintegrada. Este trabajo, presenta desarrollo un instrumento teórico metodológico para la toma decisiones respecto al origen, crecimiento densificación del hábitat popular Partido La Plata. Se identificado tierras vacantes susceptibles ser ocupadas partir estudio su accesibilidad, servicios básicos infraestructura, equipamiento, espacios recreativos...
Objetivo: este trabajo presenta los resultados de un estudio confort térmico en aulas ventiladas naturalmente cuatro colegios típicos la ciudad Cali, Colombia, Suramérica. Se realizó clima tropical cálido sin estaciones y periodos lluviosos secos. Materiales métodos: total 535 estudiantes entre 6 12 años edad fueron encuestados sobre su sensación térmica. Simultáneamente, se midieron parámetros ambientales interiores exteriores temperatura del aire, humedad relativa, velocidad viento...
Access to housing in low-income sectors brings up the need for a relevant reflection on Latin America. In this context, wood-based Modular Housing Solution (MHS) has been developed neighborhood outskirts of CABA called La Plata, oriented improvement working-class sectors, and managed by labor cooperative, university, scientific-technical sector. The objective is evaluate thermal light behavior airtightness conditions building envelope wooden MHS Plata district warm-temperate climate. For...