A5036663477- Advanced Image and Video Retrieval Techniques
- Advanced Steganography and Watermarking Techniques
- Virus-based gene therapy research
- Digital Media Forensic Detection
- Geology and Paleoclimatology Research
- Video Analysis and Summarization
- Advanced Image Processing Techniques
- Air Quality and Health Impacts
- Advanced Vision and Imaging
- Nanoparticle-Based Drug Delivery
- Image Retrieval and Classification Techniques
- Image Enhancement Techniques
- Cancer Research and Treatments
- Non-Invasive Vital Sign Monitoring
- Nanoplatforms for cancer theranostics
- Air Quality Monitoring and Forecasting
- Atmospheric chemistry and aerosols
- Land Use and Ecosystem Services
- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Coastal wetland ecosystem dynamics
- Video Surveillance and Tracking Methods
- ECG Monitoring and Analysis
- Pacific and Southeast Asian Studies
- Advanced Optical Imaging Technologies
Tianjin University
2015-2024
Shanxi Agricultural University
2024
China Academy of Space Technology
2024
China University of Geosciences
2022-2023
University of Maryland, College Park
2020-2022
Zhengzhou University
2015-2020
Liaoning University
2019
Shenyang Pharmaceutical University
2017-2018
Chongqing University
2016-2018
University of Waterloo
2016-2017
Interleukin-12 (IL-12) has emerged as one of the most potent agents for anti-tumor immunotherapy. However, potentially lethal toxicity associated with systemic administration IL-12 precludes its clinical application. Here we redesign molecule in such a way that efficacy is not compromised, but toxic effects are eliminated. Deletion N-terminal signal peptide can effect change by preventing secretion from cells. We use newly designed tumor-targeted oncolytic adenovirus (Ad-TD) to deliver...
In this paper, we propose a robust-hash function based on random Gabor filtering and dithered lattice vector quantization (LVQ). order to enhance the robustness against rotation manipulations, conventional filter is adapted be invariant, rotation-invariant randomized facilitate secure feature extraction. Particularly, novel dithered-LVQ-based scheme proposed for robust hashing. The well suited hashing with several desirable features, including better tradeoff between discrimination, higher...
Sonic hedgehog (Shh) is a morphogen critically involved in development that reexpressed atherosclerotic lesions. It also stimulates proliferation of vascular smooth muscle cells (SMCs). Autophagy SMCs known to promote SMC survival and increase plaque stability. The aim this study was investigate whether Shh induces autophagy SMCs. Our showed both protein microtubule-associated 1 light chain 3 (LC3)-II were increased within neointimal lesions mouse common carotid arteries. In cultured aortic...
Abstract A comprehensive investigation using the air quality network and meteorological data of China in 2015 showed that PM 2.5 driven by cold surges from ground level could travel up to 2000 km northern southern within two days. Air pollution is more severe prominent during winter north due seasonal variations energy usage, trade wind movements, industrial emissions. In February 2015, traveling caused a temporary increase concentration Shanghai. Subsequently, Xiamen increased high 80 µg/m...
Background Local recurrence and remote metastasis are major challenges to overcome in order improve the survival of patients with cancer after surgery. Oncolytic viruses a particularly attractive option for prevention postsurgical disease as they offer non-toxic treatment that can directly target residual tumor deposits beneficially modulate systemic immune environment is suppressed post surgery allows escape from control. Here, we report novel Vaccinia virus (VV), VVΔTKΔN1L (with deletion...
Video shot boundary detection is the initial and fundamental step towards video indexing, browsing retrieval. Great efforts have been paid on developing accurate algorithms. However, high computational cost in becomes a bottleneck for real-time applications. The problem of making balance between accuracy speed addressed this paper, novel fast framework presented. general that employs pre-processing techniques can improve both precision. In stage, adaptive local thresholding adopted to...
Robust and compact content representation is a fundamental problem in image processing. The recently proposed polar harmonic transforms (PHTs) have provided set of powerful tools for representation. However, two-dimensional cannot handle color holistic manner. To extend the nice properties PHTs to processing, we generalize from complex field hypercomplex this letter, quaternion (QPHTs) are developed based on algebra. Furthermore, QPHTs studied via computation, including orthogonality...
Robust image hashing, which maps the perceptual contents of to a short digest, is key technique for tackling challenges content-based indexing, searching and copyright protection. In this letter, we propose quaternion invariance based hashing algorithm that can fuse complementary visual features compact hash. The proposed leverages polar cosine transform holistically capture spatial chromatic characteristics digital image, rotation-invariant are derived from phase information in frequency...
MicroRNAs (miRNAs), a class of small noncoding RNA molecules, can manipulate the expressions endogenous tumor-related genes, and are implicated in development progression wide type tumors. In this study, investigation from real-time quantitative PCR revealed that miRNA-16-5p was downregulated breast carcinoma tissues cells, coupled with elevations HIF-α VEGFA protein expressions, compared normal tissues. Lentiviral armed miR-16-5p markedly increased levels MCF-7 MDA-MB-231 to blank NC...
Image fingerprinting is a technique that summarizes the perceptual characteristics of digital image into an invariant digest, and it one most effective solutions for rights management. Most conventional algorithms were developed by assembling manually designed feature extractor quantizer, which requires extensive expert knowledge may not capture intrinsic or abstract visual image. Focusing on content identification related applications, we propose data-driven algorithm in this paper, where...
Most existing dehazing algorithms recover haze-free image by solving the hazy imaging model using estimated transmission map and global atmospheric light. However, inaccurate estimation of these variables strong assumptions result in unrealistic results. In this paper, we use adversarial game between a pair neural networks to accomplish end-to-end photo-realistic dehazing. To avoid uniform contrast enhancement, generator learns simultaneously restore capture non-uniformity haze. The modules...
An emerging research direction considers the inverse problem of inferring electrocardiogram (ECG) from photoplethysmogram (PPG) to bring about synergy between easy measurability PPG and rich clinical knowledge ECG facilitate preventive healthcare. Previous reconstruction using a universal basis has limited accuracy due lack representative power. This paper proposes cross-domain joint dictionary learning (XDJDL) framework maximize expressive power for two signals. Building on K-SVD technique,...
We propose in this paper a low-rank and sparse decomposition based image hashing algorithm, aiming to summarize the structural information salient components of digital compact digest. More specifically, we leverage compressive sampling random projection separately aggregate approximation input spatial layout into binary hash. Owing its capability capturing fusing intrinsic visual characteristics, proposed work demonstrates high robustness discriminability. As observed content identification...
The aim of this study was to prepare and evaluate ion-activated in situ gel ophthalmic drug delivery system based on κ-carrageenan (KC), using acyclovir as a model drug, hydroxypropyl methylcellulose (HPMC) the viscosity agent hydroxypropyl-β-cyclodextrin (HP-β-CD) penetration enhancer. two ternary phase diagrams exhibited effect K+ Ca2+ sol-to-gel transition, which turned out that KC more sensitive K+. optimal matrix (prepared from HPMC) optimized with vitro release test. apparent...
Content fingerprinting recently emerges as an effective nonintrusive solution for copyright protection. Fingerprinting algorithm maps the perceptual contents of media file to invariant digest, so that unauthorized copies can be identified via fingerprint comparison. This letter presents a distortion-resistant sparse coding strategy image simulates hierarchical information processing flow visual system. Sparse coding, which seeks small set atoms best represent input signal, helps detect...
The aim of the study was to develop actarit double-layered osmotic pump tablets overcome weak points common tablets, such as short half-life and large plasma concentration fluctuations. Single factor experiment orthogonal test were applied optimize formulation; pharmacokinetic performed in beagle dogs adopting reference tablets. optimal formulation follows: drug layer: 150 mg actarit, 240 PEO-N80, 50 NaCl; push 140 PEO-WSR303, 20 coating solution: 30 g cellulose acetate 6 PEG 4000 1000 ml...
This paper presents a computational solution that enables continuous cardiac monitoring through cross-modality inference of electrocardiogram (ECG). While some smartwatches now allow users to obtain 30-second ECG test by tapping built-in bio-sensor, these short-term tests often miss intermittent and asymptomatic abnormalities functions. It is also infeasible expect persistently active user participation for long-term in order capture other types abnormalities. To alleviate the need attention...
A schematic illustration of a novel formulation that can be instilled on the surface eyes (A) and results <italic>in vivo</italic> studies (B C).