A5017476386- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Tunneling and Rock Mechanics
- Drilling and Well Engineering
- Advanced machining processes and optimization
- Neurosurgical Procedures and Complications
- Analytical Chemistry and Chromatography
- Advanced Welding Techniques Analysis
- Welding Techniques and Residual Stresses
- Analytical chemistry methods development
- Traumatic Brain Injury and Neurovascular Disturbances
- Microstructure and Mechanical Properties of Steels
- Kruppel-like factors research
- Extraction and Separation Processes
- Neuropeptides and Animal Physiology
- Mass Spectrometry Techniques and Applications
- Spacecraft and Cryogenic Technologies
- Inflammatory Biomarkers in Disease Prognosis
- Cancer-related gene regulation
- Autophagy in Disease and Therapy
- Heme Oxygenase-1 and Carbon Monoxide
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Diamond and Carbon-based Materials Research
- S100 Proteins and Annexins
Wenzhou Medical University
2022-2025
China Coal Technology and Engineering Group Corp (China)
2011-2024
Quzhou City People's Hospital
2014-2024
China Coal Research Institute (China)
2014-2021
Gas Technology Institute
2014
Intracerebral hemorrhage (ICH) is a common cerebrovascular disease characterized by high mortality and disability rates. Neuritin, significantly expressed in injured brain tissues, implicated the molecular mechanisms underlying acute injury. We aimed to explore prognostic predictive value of serum neuritin ICH. In this prospective cohort study, levels were measured at admission 202 patients, on post-ICH days 1, 3, 5, 7, 10 54 these time enrollment 100 healthy controls. The Glasgow Coma Scale...
Natural gas hydrate (NGH) holds great promise as a source of clean energy. It is critical for acquiring the largest possible in situ NGH core eigen features and resource assessment. However, existing coring technology has limitations, such temperature increments, limited diameters, low rates, complex structures. Therefore, this study designs proposes an freezing (NGHFC) method verifies capacities NGHFC laboratories experimental wells. Results suggest that shows good heat-retention...
Background The neutrophil-to-lymphocyte ratio (NLR) is a biomarker reflecting the balance between inflammation (as indicated by neutrophil count) and adaptive immunity lymphocyte count). We aimed to estimate ability of NLR at admission day 1 for predicting stroke outcome after two reperfusion therapies: intravenous thrombolysis (IVT) mechanical thrombectomy (MT). Methods A retrospective analysis was performed on patients who received recombinant human tissue plasminogen activator and/or...
An ionic liquid foam floatation coupled with dispersive liquid-liquid microextraction method was proposed for the extraction and concentration of 17-α-estradiol, 17-β-estradiol-benzoate, quinestrol in environmental water samples by high-performance chromatography fluorescence detection. 1-Hexyl-3-methylimidazolium tetrafluoroborate applied as foaming agent flotation process solvent microextraction. The introduction ion-pairing salting-out NH4 PF6 beneficial to improvement recoveries...
For hard rock drilling in coal mine, the efficiency and service life of polycrystalline diamond compact bit are very low. To overcome these shortcomings, bionic technology is applied to design processing bit. The body cutter designed as structures, test carried out. Test results show that, when fine sandstone with hardness greater than 9, performance significantly improved. Comparing Φ113-mm concave bit, A-type increase by 54% 230%, respectively, B-type 345% 204%, which that can provide a...
In order to grasp the rock breaking mechanical characteristics of arc-shaped PDC bit, and guide optimization design bit structure, theoretical calculation models cutting parameters cutters were established. Taking Φ94 mm tri-wing as an example, results show that, with increase radial distance, area, arc length force approximately first then decrease; maximum is concentrated on number 5 6 cutters, which makes these two very easy be damaged in advance. Based this, a four-wing was designed,...
Absent in melanoma 2 (AIM2) is implicated inflammatory processes. We measured serum AIM2 with intent to unveil its predictive significance for stroke-associated pneumonia (SAP) and functional prognosis following acute intracerebral hemorrhage (ICH).
Abstract Objective Mesencephalic astrocyte-derived neurotrophic factor (MANF) expressions are dramatically up-regulated in injured brain tissues, thereby conferring neurological protective effects. We intended to determine significance of serum MANF as a prognostic biomarker intracerebral hemorrhage (ICH). Methods In this prospective, observational study done from February 2018 July 2021, 124 patients with new-onset primary supratentorial ICH were consecutively enrolled. Also, group healthy...
Annexin A7 (ANXA7), a calcium-dependent phospholipid-binding protein, may act to aggravate brain injury. This study aimed assess the clinical utility of serum ANXA7 as predictor severity, early neurological deterioration (END), and prognosis after intracerebral hemorrhage (ICH).A total 126 ICH patients healthy controls were enrolled. Symptomatic severity was evaluated utilizing National Institutes Health Stroke Scale (NIHSS) score. The lesion volume measured according ABC/2 method. END...
Isoprene is a typical physiological marker that can be used to screen for chronic liver disease. This work developed portable micro-integrated chromatography analysis system based on micro-electromechanical technology, nanomaterials technology and embedded microcontroller technology. The integrated components such as graphene oxide quantum dots modified semi-packed microcolumn, In2O3nanoflower (NF) gas-sensitive detector 3D printed miniature solenoid valve group. effectiveness of the...
An important way to improve overall drilling efficiency is crease each bit's life and footage,, high matrix diamond coring bits are especially used in deep hole. In this paper, the brazing process of designing manufacturing bit was introduced. Firstly, impregnated blocks were manufactured using hot pressing method; secondly, new drill steel body including waterway processed; end, welded on process. Using process, a φ75/54.5 two-stage developed, its work layer 15 mm, experimental results...
The double-connection structure of bionic joints mining drill pipes has solved the problem drop caused by fatigue cracks. However, with low-melting-point elastic–ductile alloy filling in joint, thread on joint cannot be hardened high-temperature surface hardening treatments such as quenching and nitriding, making it prone to gluing or excessive wear. In this paper, feasibility diamond-like film deposition a pipe was studied. A tungsten transition used improve thickness interfacial bond...
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<title>Abstract</title> 42CrMo medium carbon steel and 36Mn2V alloy were successfully jointed using continuous drive friction welding. The effects of forging pressure post-weld heat treatment on microstructure mechanical properties joints investigated in detail. Results reveal that with increasing the pressure, tensile yield strength increase firstly then decrease. as-welded joint highest (708 MPa), largest elongation (14.2%), high impact toughness (57.24 J) obtained 35MPa pressure. After...
Nuclear factor erythroid 2-related 2 (Nrf2) is a key transcriptional for antioxidant response element-regulated genes. The purpose of this study was to assess the prognostic role serum Nrf2 in intracerebral hemorrhage (ICH).In prospective observational study, levels 115 acute supratentorial ICH patients and controls were gaged. Early neurologic deterioration (END) defined as an increase four or greater points National Institutes Health Stroke Scale (NIHSS) score death at post-stroke 24 h. A...
Fatigue fracture is the main failure form of mining drill pipe joints, which directly leads to occurrence drop accidents. Based on principle engineering bionics, spine structure and kinematic behavior characteristics cheetah were studied; bionic design trial production joints carried out. For joint, it separates torsion transmission function from connection function, when joint fails, still effective, so as achieve effect “breaking bones connecting ribs.” The mechanical flow field properties...