A5045224092- Insect-Plant Interactions and Control
- Insect behavior and control techniques
- Hemiptera Insect Studies
- Hedgehog Signaling Pathway Studies
- Epigenetics and DNA Methylation
- Acute Myeloid Leukemia Research
- Animal Behavior and Reproduction
- Developmental Biology and Gene Regulation
- Genetic and Kidney Cyst Diseases
- Erythrocyte Function and Pathophysiology
- Neurobiology and Insect Physiology Research
- Maritime Security and History
- Photosynthetic Processes and Mechanisms
- Amino Acid Enzymes and Metabolism
- Phosphodiesterase function and regulation
- Global Political and Social Dynamics
- Genetics and Neurodevelopmental Disorders
- Invertebrate Immune Response Mechanisms
- Hemoglobinopathies and Related Disorders
- Protein Hydrolysis and Bioactive Peptides
- RNA modifications and cancer
- Steroid Chemistry and Biochemistry
University Children’s Hospital Basel
2019-2023
University of Basel
2023
Max Planck Institute of Molecular Cell Biology and Genetics
2019-2022
TU Dresden
2020-2022
National and Kapodistrian University of Athens
2016-2018
Article6 October 2020Open Access Source DataTransparent process Glycolysis regulates Hedgehog signalling via the plasma membrane potential Stephanie Spannl Corresponding Author [email protected] orcid.org/0000-0001-5999-1564 Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany Search for more papers by this author Tomasz Buhl Biotechnologisches Zentrum, Technische Universität Ioannis Nellas Salma A Zeidan K Venkatesan Iyer Physics Complex Systems, Helena Khaliullina...
The NFIA-ETO2 fusion is the product of a t(1;16)(p31;q24) chromosomal translocation, so far, exclusively found in pediatric patients with pure erythroid leukemia (PEL). To address role for pathogenesis disease, we facilitated expression murine erythroblasts (EBs). We observed that significantly increased proliferation and impaired differentiation erythroleukemia cells primary fetal liver-derived EBs. However, NFIA-ETO2-expressing EBs acquired neither aberrant vitro clonogenic activity nor...
Abstract Ecdysteroids secreted by the prothoracic gland (PG) cells of insects control developmental timing their immature life stages. These have been historically considered as carrying out a single function in insects, namely biochemical conversion cholesterol to ecdysteroids and secretion. A growing body evidence shows that PG receive multiple cues during insect development so we tested hypothesis they carry more than just one insects. We characterised molecular nature profiles cell...
The prothoracic gland (PG), the principal steroidogenic organ of insects, has been proposed as a model for steroid hormone biosynthesis and regulation. To validate robustness model, we present an analysis accumulated transcriptomic data from PGs two species, Drosophila melanogaster Bombyx mori. We identify that common core components in both species are encoded by nine genes. Five these Halloween genes whose expression differs substantially between species. conclude can be synthesis...
Report22 September 2022Open Access Transparent process Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc Ioannis Nellas orcid.org/0000-0001-8976-1487 Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany Excellence Cluster, Physics of Life, Technische Universität Contribution: Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Writing - original draft, review & editing Search more papers by...