A5067542058- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Treatment of Major Depression
- Mental Health and Psychiatry
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Psychosomatic Disorders and Their Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Transcranial Magnetic Stimulation Studies
- Stress Responses and Cortisol
- Electroconvulsive Therapy Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Mental Health Treatment and Access
- Diet and metabolism studies
- Obsessive-Compulsive Spectrum Disorders
- Neurotransmitter Receptor Influence on Behavior
- Genetic Associations and Epidemiology
- Personality Disorders and Psychopathology
- Attention Deficit Hyperactivity Disorder
- Psychoanalysis and Psychopathology Research
- Family Caregiving in Mental Illness
- Neuroscience and Music Perception
- Face Recognition and Perception
- Genomic variations and chromosomal abnormalities
Centre Hospitalier Le Vinatier
2016-2025
Centre de Recherche en Neurosciences de Lyon
2013-2025
Inserm
1991-2025
Centre National de la Recherche Scientifique
1997-2025
Université Claude Bernard Lyon 1
2013-2024
Fondation FondaMental
2015-2024
Hôpital Albert-Chenevier
2016-2024
Lyon College
2007-2023
Institut de Psychiatrie et Neurosciences de Paris
2022
Université Paris Cité
2022
OBJECTIVE: The possibility that delusions of influence could be related to abnormal recognition one's own actions was investigated in persons with schizophrenia. METHOD: Schizophrenic patients (N=6) and without (N=18) were compared normal subjects (N=29) on an action task. image a virtual right hand holding joystick presented the through mirror so superimposed their real joystick. Subjects executed discrete movements different directions. Angular biases temporal delays randomly introduced...
Several groups have reported weak evidence for linkage between schizophrenia and genetic markers located on chromosome 22q using the lod score method of analysis. However these findings involved different methods analysis, so were not directly comparable. To resolve this issue we performed a combined analysis genotypic data from marker D22S278 in multiply affected schizophrenic families derived 11 independent research worldwide. This was chosen because it showed maximum three datasets...
Epidemiological studies of schizophrenia suggest that this disorder has a substantial genetic component. Cognitive and social abilities, as well the volumes brain regions involved in emotion processing, have been found to be distributed along continuum when comparing patients, siblings controls, with showing intermediate scores.To establish whether facial expression recognition is impaired unaffected patients.Emotion gender were evaluated three-group pre-post study design drug-naive patients...
Abnormal decoding of social information has been associated with the conversion from prodromal Alzheimer's disease (AD) to dementia. Since distributed neural networks involved in face processing are differentially affected and dementia states AD Fronto-Temporal Dementia (FTD), we hypothezed a differential impairment these populations. Facial expression, gender gaze direction abilities were examined patients probable amnesic Mild Cognitive Impairment (aMCI, N = 10) fulfilling criteria for AD,...
We report three new mutations in patients with myophosphorylase deficiency (McArdle disease). A splice-junction mutation (G-to-A transition at the 5' end of intron 14) and a missense (CTG to CCG codon 291, changing an encoded leucine proline) were identified Caucasian who heterozygous for common reported elsewhere (CGA [Arg] TGA [stop]) 49. The destroyed consensus sequence splice site, cryptic site 67 bp upstream was recognized instead. As result, there 67-bp deletion 3'-terminal region exon...
As almost all mental disorders are associated with increased suicidal-related behavior, anhedonia might be a trans-diagnostic dimension to target for suicide prevention.For this 3-year-long prospective study, 2,839 outpatients mood were recruited. They divided in: (a) two groups according the occurrence or not of suicidal ideation during follow-up, and (b) attempts follow-up. Anhedonia was assessed using composite score (the French version 14-item Snaith-Hamilton Pleasure Scale item 13 Quick...
Because of an association between sexual aneuploidies and schizophrenia, because schizophrenic siblings have been found to be more often the same than opposite sex, susceptibility locus for schizophrenia is thought lie within pseudoautosomal region sex chromosomes. We analysed 33 sibships comprising 18 pairs, 13 trios, 2 quartets affected siblings, support non-random segregation alleles at DXYS14 in siblings. These findings are consistent with hypothesis favour a genetic linkage disease.
Background: Impaired facial expression recognition in schizophrenia patients contributes to abnormal social functioning and may predict functional outcome these patients. Facial processing involves individual neural networks that have been shown malfunction schizophrenia. Whether a selective deficit or more global impairment face remains controversial. Objective: To investigate whether with exhibit emotional recognition, compared major depression healthy control subjects. Methods: We studied...
Investigating the relative severity of emotion recognition deficit across different clinical and high-risk populations has potential implications not only for prevention, diagnosis treatment these diseases, but also our understanding neurobiological mechanisms perception itself. We reanalyzed data from 4 studies in which we examined facial expression gender using same tasks stimuli. used a standardized bias-corrected measure effect size (Cohen's D) to assess extent impairments frontotemporal...