- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Anesthesia and Sedative Agents
- Tracheal and airway disorders
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Climate Change and Health Impacts
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Patient Safety and Medication Errors
- Anesthesia and Pain Management
- Family and Patient Care in Intensive Care Units
- Innovations in Medical Education
- Trauma and Emergency Care Studies
- Dysphagia Assessment and Management
- Organ Donation and Transplantation
- Simulation-Based Education in Healthcare
- Neonatal Respiratory Health Research
- Autopsy Techniques and Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
Jawaharlal Institute of Post Graduate Medical Education and Research
2016-2025
Justus-Liebig-Universität Gießen
2025
University of Alabama at Birmingham
2022
Society of Critical Care Medicine
2021
<h3>Importance</h3> Obesity, diabetes, and hypertension are common comorbidities in patients with severe COVID-19, yet little is known about the risk of acute respiratory distress syndrome (ARDS) or death COVID-19 metabolic syndrome. <h3>Objective</h3> To determine whether associated an increased ARDS from COVID-19. <h3>Design, Setting, Participants</h3> This multicenter cohort study used data Society Critical Care Medicine Discovery Viral Respiratory Illness Universal Study collected 181...
Sepsis poses a significant global health challenge in low- and middle-income countries (LMICs). Several aspects of sepsis management recommended international guidelines are often difficult or impossible to implement resource-limited settings (RLS) due issues related cost, infrastructure, lack trained healthcare workers. The Indian Society Critical Care Medicine (ISCCM) drafted position statement for the RLS focusing on India, facilitated by task force 18 intensivists using Delphi process,...
The care bundle approach is a set of evidence-based practices that when performed collectively and reliably have been shown to improve the patient outcome.To evaluate impact on reducing device-associated infections (DAIs).The study was conducted at tertiary hospital, South India. period from January 2016 September which divided into three phases, each comprising 3 months.During implementation phase, forms were implemented in all Intensive Care Units (ICUs) ICU staff given basic education...
Coronavirus disease 2019 (COVID-19) predominantly involves the lungs, albeit many other organ systems, including hypothalamic-pituitary-adrenal (HPA) axis, can be affected due to expression of angiotensin-converting enzyme 2 (ACE2) binding receptor. Few studies have reported involvement adrenal gland and HPA axis during acute phase COVID-19; however, data on long-term effect COVID-19 after infection is scarce.To assess compare changes in mild, moderate severe categories at ≥ 3 months...
BackgroundIn the era of COVID-19 pandemic, there is an upsurge healthcare-associated infections (HAI) in COVID intensive care units (ICUs), which can be reduced by following proper hand hygiene (HH) practice. Performing HH auditing ICU and providing timely feedback to stake holders crucial reduce HAIs.MethodsFrom November 2020- April 2021, audit was conducted ICUs. complete adherence rate (HHCAR), partial (HHPAR) total (HHTAR) were analyzed. Profession-specific HHTAR moment-specific (for...
Background and Aims: Perineural intravenous dexmedetomidine as a local anaesthetic adjunct has not been compared previously in fascia iliaca compartment block (FICB). The aim of this study was to compare the efficacy side effect profile an bupivacaine single dose FICB for femur surgeries two different routes i.e., perineural route. Methods: Eighty American Society Anesthesiologists physical status 1, 2 or 3 patients posted were randomised receive ultrasound guided FICB. Intravenous group(ID)...
Conventional age-based formulae often fail to predict correct size of endotracheal tube (ETT). In this study, we evaluated usefulness ultrasound in determining appropriate and derived a formula which enables us size.A total 41 American Society Anesthesiologists' physical status 1 2 children the age group 2-6 years, undergoing elective surgery under general anaesthesia with uncuffed ETT were included study. Ultrasonography (US) was used measure subglottic diameter after induction anaesthesia....
Abstract Background Hospitalized patients with SARS-CoV2 develop acute kidney injury (AKI) frequently, yet gaps remain in understanding why adults seem to have higher rates compared children. Our objectives were evaluate the epidemiology of SARS-CoV2-related AKI across age spectrum and determine if known risk factors such as illness severity contribute its pattern. Methods Secondary analysis ongoing prospective international cohort registry. was defined by KDIGO-creatinine only criteria....
Puerperal sterilization requires a rapid recovery of the mother so that she can take care her child. Propofol with fentanyl (PF) is an option, but associated intraoperative hypotension, respiratory depression and unsatisfactory postoperative profile. ketamine (PK) appears to be alternative in terms haemodynamic stability analgesia.This randomized clinical trial involved 60 patients who were scheduled undergo puerperal sterilization, belonged American society anaesthesiologists (ASA) physical...
"Experience is the adult learner's living text book." Adults learn best when they are actively engaged in learning process by participating, role playing and experiencing events. This experience accompanied with an intense emotional component results long lasting memory called experiential learning. One of major factors to consider that adults tend base future actions on past experience. Several teachers such as Kolb, Gibbs, Grant, Mardsen have put forward various theories about involved...
Background and Aims: Ventilator-associated pneumonia (VAP) is a major cause of morbidity mortality among patients in the Intensive Care Units (ICUs) results added healthcare costs. One methods preventing VAP to use polyurethane (PU)-cuffed endotracheal tube (ETT). This study compares incidence length ICU stay intubated with conventional polyvinyl chloride (PVC) ETT PU-cuffed ETT. Methods: Eighty post-laparotomy who were mechanically ventilated for >48 h included this randomised controlled...
Context: Methylene blue is an inhibitor of guanylate cyclase and hence prevents vasoplegia mediated by nitric oxide in patients with sepsis. Aims: This study aimed to analyze the effect methylene on blood pressure maintenance following induction anesthesia presenting peritonitis. Subjects Methods: Thirty diagnosed have perforation peritonitis were randomized into two groups (Group MB, Group NS). Patients MB given injection 2 mg/kg over 20 min NS 50 ml normal saline min, before induction....
Purpose: Antimicrobial resistance (AMR) presents a significant threat to human health. The root cause for this global problem is irrational antimicrobial usage. stewardship (AMS) emphasises on the appropriate use of antibiotics and ensures strict implementation policy guidelines. This study was conducted evaluate impact auditing AMS programme regulating adherence usage in hospital intensive care units. Materials Methods: prospective interventional study. It consisted pre-implementation...
Background Arterial sampling, which is the gold standard for measuring lactate levels in sepsis, more painful, requires experience and associated with a higher incidence of morbidity, when compared venous sampling. This study attempted to measure correlation agreement between arterial peripheral (PV) central (CV) lactate, objective test interchangeability two possibly support use resuscitating patients sepsis. Methods Eighty-seven admitted critical care unit our hospital diagnosis sepsis or...
This study attempts to assess the safety of low-flow anaesthesia (LFA) at fixed flow rates with particular reference incidence a decline in FiO(2) below safe levels 0.3 and determine whether LFA can be used safely absence an monitor.A total 100 patients undergoing procedures under general fresh gas flows 300 ml/min O(2) N(2)O were monitored while maintaining dial setting isoflurane 1.5% for 2 h. The changes composition analysed even single recording <0.3 was considered sufficient render...
Introduction: Endotracheal intubation and mechanical ventilation are the most frequently used life-sustaining interventions in critical care. Prolonged can lead to post-extubation dysphagia, affecting individual’s nutritional level communication ability. Thereupon, this study aims assess effectiveness of swallowing oral care resuming intake increasing salivary flow patients. Methods: A randomized controlled trial was conducted units a tertiary setting, where 92 patients who had undergone...
Airway ultrasound (US) provides a dynamic assessment of the airway. In conjunction with other imaging techniques such as computerised tomographic (CT) scan and magnetic resonance (MRI), ultrasonography airway can influence management decisions. There is some evidence to support its use in prediction difficult by measuring pre-tracheal soft-tissue thickness pre-epiglottis space thickness. However, vocal cord movements may replace direct visualisation future. addition, measurements subglottic...
Introduction: During the course of systemic inflammation, most immune cell types get activated to a certain degree as part of, or contributing to, cascade physiopathological events.Whether for some cells, classically phagocytes innate system, it is clear that direct sensing pathogen-associated molecular patterns leads activation initiating picture not so natural killer (NK) cells.While NK cells have been shown express toll-like receptors (TLR), role these on NKs during inflammation has...