- Per- and polyfluoroalkyl substances research
- Gestational Diabetes Research and Management
- Air Quality and Health Impacts
- Pregnancy and preeclampsia studies
- Chemical Analysis and Environmental Impact
- Folate and B Vitamins Research
- Biotin and Related Studies
- Vitamin D Research Studies
- Birth, Development, and Health
- Insect and Pesticide Research
- Cardiovascular Issues in Pregnancy
- Fluorine in Organic Chemistry
Guangdong Provincial People's Hospital
2021-2024
Southern Medical University
2023-2024
Guangdong Academy of Medical Sciences
2021-2024
Shanghai Jiao Tong University
2021-2023
XinHua Hospital
2021-2023
Humans are widely exposed to per- and polyfluoroalkyl substances (PFAS). As fetal stage is a critical window for neurodevelopment, it important know if in utero exposure PFAS affects neurodevelopment. However, previous human studies both limited inconsistent. To investigate the relationship between during early pregnancy neurodevelopmental status at 2 years of age prospective cohort study. We measured 10 maternal plasma samples collected prior 16 weeks gestation Shanghai Birth Cohort Study...
Accumulating evidence suggests that environmental pollutants may contribute to the occurrence of congenital heart defects (CHDs). However, no previous studies have evaluated impact perfluoroalkyl substances (PFAS), persistent pollutants, on CHDs. This exploratory study aimed generate testable hypotheses association between gestational PFAS and risk A nested case-control was conducted in a cohort 11,578 newborns. Exposure odds ratios were compared 158 CHD cases non-malformed controls...
Importance The association of folate supplementation with congenital heart disease (CHD) prevention is controversial. Objective To examine the maternal serum levels at early to midpregnancy CHD risk in offspring. Design, Setting, and Participants This case-control study recruited participants from one China’s largest cardiac referral centers between 2015 2018. cases non-CHD controls were matched according age a ratio 1:4. Data analyzed May August 2023. Exposures Maternal folate, vitamin B 12...
Epidemiological evidence on the association between prenatal exposure to Perfluoroalkyl substances (PFAS) and child cognition remains unclear. Thus, we aimed investigate whether PFAS is associated with intelligence quotient (IQ) in offspring. This study population included 2031 mother-child pairs Shanghai Birth Cohort (SBC) enrolled during 2013–2016. Ten were measured by high-performance liquid chromatography/tandem mass spectrometry (HPLC/MS-MS) maternal plasma samples collected early...
BackgroundHumans are widely exposed to per- and polyfluoroalkyl substances (PFAS). Fetal stage is a critical window for neurodevelopment may have life-time impact. Whether in utero exposure PFAS affects fetal remained uncertain.ObjectivesTo investigate the relationship between during early pregnancy neurodevelopmental status at 2 years of age prospective cohort study.MethodsWe measured 10 maternal plasma samples collected prior 16 weeks gestation Shanghai Birth Cohort Study 2013 2016....