Abstract A 77-year-old woman with recently diagnosed breast cancer underwent 68 Ga-labeled DOTA-ibandronic acid ( Ga-DOTA-IBA) PET/CT scan for the evaluation of bone metastases. The examination revealed increased tracer uptake, indicating that cervical vertebrae presented osteoblastic metastasis. Interestingly, also showed enhanced activity Ga-DOTA-IBA.

Few reports exist on the treatment of transverse patellar fractures (TPFs) using absorbable cannulated screws and high-strength sutures, most sutures lack good biomechanics clinical trials. Therefore, this study aimed to demonstrate biomechanical stability efficacy tension-band combined with (TBSAS) in treating TPFs (AO/OTA 34 C1).

Introduction 68 Ga labeled DOTA-Ibandronate ( Ga-DOTA-IBA) positron emission tomography/computed tomography (PET/CT), is a novel bone-targeting imaging tracer and promising diagnostic method for bone metastases detection. Therefore, this study aimed to compare Ga-DOTA-IBA PET/CT the 99m Tc-MDP whole-body scan (WBBS) detecting in breast cancer (BC). Materials methods In prospective study, 45 women with BC underwent via WBBS. Clinical demographic information as well features were recorded. The...

68 Ga-labeled DOTA-ibandronic acid ( Ga-DOTA-IBA) is a novel PET agent developed for bone tumors. In addition, Ga-DOTA-IBA uptake in nonosseous findings has also been reported. Herein, we present case of primary prostate adenocarcinoma.

Osteosarcoma development is a complex set which determined by various factors. Many patients suffered from sustained osteosarcoma growth and revealed poor response to clinical interventions. However, the underlying mechanisms of still remain unclear.In our study, we isolated tissues patients, were divided into high degree group (stage G1~G2) low G0). The expression type I collagen, integrin STAT3 in tumor analyzed immunohistochemistry or immunofluorescence. collagen-induced cells...

In the widespread adoption of chemotherapy, drug resistance has been major obstacle to tumor elimination in cancer patients. Our aim was explore role TGF-β osteosarcoma-associated chemoresistance.We performed a cytotoxicity analysis methotrexate (MTX) and cisplatin (CIS) TGF-β-treated osteosarcoma cells. Then, metabolite profile core metabolic energy pathways Saos-2 MG-63 cell extracts analyzed by 1H-NMR. We detected expression succinate dehydrogenase (SDH), STAT1, hypoxia-inducible factor...

The separate vertical wire (SVW) technique and the improved candy box (CB) have been proposed for treating inferior pole patellar fractures. However, there is still a lack of clear explanation regarding location passing through patella. Five models SVW techniques were established in different positions. Finite element analysis was then conducted to determine optimal bone tunnel position technique. Based on these findings, six groups finite created CB techniques. maximum displacement stress...

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Reportedly, the elevated expression of survivin has been observed in several tumor types, strictly involved development. In present study, we detected tissues derived from patients with chemoresistant osteosarcoma when compared those chemosensitive patients. Importantly, knockdown cells significantly suppressed cell proliferation and chemoresistance both vitro vivo. Simultaneously, chemotherapy mediates upregulation through a survivin-based selective killing effect, resulting development...

We aimed to investigate the adoption of treatment patterns for hip fractures combined with minimally invasive surgical fragility pelvis in older individuals and reviewed analysed efficacy feasibility.From September 2017 February 2021, 135 were admitted our hospital. retrospectively patients who received or conservative treatments. The general preoperative data, including sex, age, disease duration, cause injury, AO/OTA type, BMI, bone mineral density, time from injury admission, surgery, ASA...

There are multiple surgical options for treatment of chronic Achilles tendon (AT) rupture according to the classifications and length defect. However, no gold standard method has been confirmed, there is clear evidence support superiority 1 procedure over others. This study aimed evaluate long-term clinical outcome flexor hallucis longus (FHL) transfer AT with large Clinical data patients treated FHL due between January 2009 October 2019 were reviewed retrospectively. All cases presented...

Reconstruction plates (RPs) are commonly used in scapular neck fractures (SNFs): however, RPs have many defects. In this study, we evaluated a newly designed anatomical locking compression plate (SNALCP).An SNF finite element model (Miller-type IIB) was constructed. Plates were subsequently implanted into the scapula and fixed with screws that grouped according to used: SNALCP (A) RP (B). Finally, loads applied record analyze performance.Under lateral, anteroposterior, vertical loads,...

Diagnosis is widely performed using convolutional neural networks (CNN). There are, however, limitations to CNN in non-Euclidean space. Based on the superiority of graph (GCN) space, GCN was adopted this paper. In order optimize convolution process, kernel approximated by four orthogonal polynomials, Chebyshev, Legendre, Laguerre, and Hermite. Then, ChebyNet, LegenNet, LargerNet, HermiNet models are constructed these polynomials. According experimental results, superior when time-domain...

Abstract 18 F-FDG PET/CT may sometimes not be an ideal imaging method for gastric adenocarcinoma. Because of the unstable physiological uptake in gastrointestinal tract and muscles, it interfere with detection lesions. We present a case intramucosal adenocarcinoma detected by 68 Ga-FAPI patient nasopharyngeal carcinoma.

Abstract Background Maintaining effective reduction and firm fixation in inferior pole patellar fractures is a highly challenging task. There are various treatment methods available; although tension-band wiring combined with cerclage (TBWC) the mainstream approach, its effectiveness limited. Herein, we propose evaluate new technique called candy box (CB), based on separate vertical (SVW), for of fractures. Specifically, provide biomechanical evidence clinical application. Methods Five...

Vibration signals play a crucial role in mechanical fault diagnosis. However, they are susceptible to various noise disturbances, presenting challenges for reliable detection. We propose an end-to-end Cross-task Attention Joint Learning (CTA-JL) model that concurrently denoises and diagnoses faults noisy signals. This utilizes multi-task encoder, composed of task-shared task-specific feature encoding units, along with information exchange unit (CTA) mechanism, fostering across different...