A5070593550- Esophageal and GI Pathology
- Pluripotent Stem Cells Research
- Cardiac electrophysiology and arrhythmias
- CRISPR and Genetic Engineering
- Congenital heart defects research
- Sarcoma Diagnosis and Treatment
- Lower Extremity Biomechanics and Pathologies
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Sports injuries and prevention
- Tracheal and airway disorders
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Cardiac tumors and thrombi
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Bone health and osteoporosis research
- Cardiac Structural Anomalies and Repair
- Pelvic and Acetabular Injuries
- Cancer-related molecular mechanisms research
- Medical Imaging Techniques and Applications
- Total Knee Arthroplasty Outcomes
- Pharmacological Effects of Natural Compounds
- Cancer, Stress, Anesthesia, and Immune Response
- Tissue Engineering and Regenerative Medicine
Southwest Medical University
2022-2025
Zhejiang Chinese Medical University
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Blood Center of Zhejiang Province
2025
Nanjing Tech University
2025
Affiliated Hospital of Southwest Medical University
2021-2024
Chengdu University of Traditional Chinese Medicine
2016-2024
Sichuan Provincial Hospital of Traditional Chinese Medicine
2022-2023
First Affiliated Hospital of Sichuan Medical University
2022-2023
Jiangxi Provincial Children's Hospital
2014-2020
Bone marrow fat increases when bone mass decreases, which could be attributed to the fact that adipogenesis competes with osteogenesis. has potential predict abnormal density and osteoporosis.To investigate predictive value of using vertebral fraction(BMFF) obtained from modified Dixon(mDixon) Quant in determination osteoporosis.Prospective.257 subjects (age: 20-79 years old; BMI: 16.6-32.9 kg/m2 ;181 females,76 males) without known spinal tumor, history trauma, dysplasia, surgery or hormone...
<title>Abstract</title> Background There is evidence that diet and nutrition are modifiable risk factors for several cancers. however, the causal impact of dietary calorie preference on cancer development remains uncertain. Methods In this study, data were sourced from a large-scale genome-wide association study (GWAS) database food liking, while information 18 types was obtained Finger R9 database. Two-sample Mendelian randomization (MR) analysis conducted to assess effects Calorie Dietary...
The ISL LIM homeobox 1 (ISL1) gene belongs to the LIM/homeodomain transcription factor family and plays a pivotal role in conveying multipotent proliferative properties of cardiac precursor cells. Mutations ISL1 are linked congenital heart disease. To further explore ISL1's human heart, we have created homozygous knockout (ISL1-KO) embryonic stem cell line using CRISPR/Cas9 system. Notably, this ISL1-KO retains normal morphology, pluripotency, karyotype. This resource serves as valuable tool...
Abstract Background Existing methods for in vitro differentiation of human pluripotent stem cells (hPSCs) into sinoatrial node-like (SANLCs) require complex and undefined medium constituents. This might hinder the elucidation molecular mechanisms involved cardiac subtype specification prevent translational application. In our study, we aimed to establish a chemically defined generate SANLCs effectively stably. Methods We induced embryonic (hESCs)/induced PSCs (hiPSCs) pan-cardiomyocytes by...
Our previous study used regional homogeneity analysis and found that activity in some brain areas of patients with ischemic stroke changed significantly. In the current study, we examined structural changes these regions by taking magnetic resonance imaging scans 11 15 healthy participants, analyzing data using voxel-based morphometry. Compared exhibited higher gray matter density left inferior occipital gyrus right anterior white tract. contrast, cerebellum, precentral gyrus, middle frontal...
The separate vertical wire (SVW) technique and the improved candy box (CB) have been proposed for treating inferior pole patellar fractures. However, there is still a lack of clear explanation regarding location passing through patella. Five models SVW techniques were established in different positions. Finite element analysis was then conducted to determine optimal bone tunnel position technique. Based on these findings, six groups finite created CB techniques. maximum displacement stress...
With the global outbreak of coronavirus disease 2019 (COVID-19), chest computed tomography (CT) is vital for diagnosis and follow-up. The increasing contribution CT to population-collected dose has become a topic interest. Radiation optimization COVID-19 patients importance in clinical practice. present study aimed investigate factors affecting detection ground-glass nodules exudative lesions among find an appropriate combination imaging parameters that optimize while effectively reducing...
The pomegranate flower is an ancient herb in traditional Chinese medicine with multiple properties. Recent studies have shown that extract beneficial, especially for hyperglycemia. In this experiment, we investigated the diastolic effect of polyphenol (PFP) on isolated thoracic aorta rats both absence and presence high glucose levels. Isotonic contractile forces were recorded from aortic rings (about 3 mm length) using BL-420F Biological Function Test System. Tissues precontracted 60 mM KCl...
Abstract Background Maintaining effective reduction and firm fixation in inferior pole patellar fractures is a highly challenging task. There are various treatment methods available; although tension-band wiring combined with cerclage (TBWC) the mainstream approach, its effectiveness limited. Herein, we propose evaluate new technique called candy box (CB), based on separate vertical (SVW), for of fractures. Specifically, provide biomechanical evidence clinical application. Methods Five...
This study aims to investigate the mechanism of Taohong Siwu Decoction (THSWD) against deep vein thrombosis (DVT) using network pharmacology and molecular docking technology. We used Traditional Chinese Medicine Systems Pharmacology database reviewed literature identify main chemical components THSWD. To find targets for DVT, we consulted GeneCards, Therapeutic Target Database, PharmGKB databases. Cytoscape 3.8.2 software construct herb-disease-gene-target networks. Additionally, integrated...
Abstract This study aims to measure anatomical data of the capitate bone, develop an external fixator for treating late-stage osteonecrosis lunate through Ilizarov technique, and evaluate its biomechanical performance. We selected eight wrist joint specimens various parameters including length, distance from junction head body proximal end, as well width distal body. Additionally, we measured these same indicators in 107 patients who had undergone X-ray examination. Based on our...
To compare the effectiveness of intramedullary nailing fixation via suprapatellar approach and medial parapatellar in semi-extended position treatment multiple tibial fractures.
Long noncoding RNAs (lncRNAs) are potential regulators of a variety cardiovascular diseases. Therefore, there is series differentially expressed lncRNAs in pulmonary arterial hypertension (PAH) that may be used as markers to diagnose PAH and even predict the prognosis. However, their specific mechanisms remain largely unknown. we investigated biological role patients with PAH. First, screened secondary ventricular septal defect (VSD) those VSD without assess differences lncRNA mRNA...
A 44-year-old male patient was referred to our department with unremarkable physical examination and laboratory data due a mass which incidentally found in the right atrial during routine examination. Transthoracic transesophageal echocardiography revealed 46 × 30 mm, well-delimited, nonmobile superior portion of atrium. Besides intracardiac mass, another low density detected adjacent pericardial cavity at cardiac computed tomography; he extracardiac appeared be caused by invasive growth...