- Heart Rate Variability and Autonomic Control
- Neuroscience of respiration and sleep
- Biochemical effects in animals
- Renin-Angiotensin System Studies
- Sodium Intake and Health
- Adenosine and Purinergic Signaling
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiovascular and exercise physiology
- Birth, Development, and Health
- High Altitude and Hypoxia
- Neonatal Respiratory Health Research
- Neuroendocrine regulation and behavior
- Cardiovascular Disease and Adiposity
- Dietary Effects on Health
- Vagus Nerve Stimulation Research
- Hormonal Regulation and Hypertension
- Anesthesia and Neurotoxicity Research
Universidade de São Paulo
2017-2024
Universidade Federal de Ouro Preto
2014-2016
Abstract In this study, we investigated some mechanisms involved in sodium-dependent hypertension of rats exposed to chronic salt (NaCl) intake from weaning until adult age. Weaned male Wistar were placed under high (0.90% w/w, HS) or regular (0.27% Cont) sodium diets for 12 weeks. Water consumption, urine output and excretion higher HS compared control. Blood pressure (BP) was directly measured by the arterial catheter found 13.8% vs Cont rats. Ganglionic blockade with hexamethonium caused...
What is the central question of this study? Is cardiovascular phenotype high blood pressure observed in rats salt loaded with 2% NaCl drinking solution a volume-dependent hypertension? main finding and its importance? Animals exposed to develop hypertension, dominance sympathetic outflow [Na
What is the central question of this study? In study, we sought to investigate whether cardiovascular responses peripheral chemoreflex activation rats recovered from protein restriction are related AT1 receptors. main finding and its importance? This study highlights fact that angiotensinergic mechanisms activated by receptors do not support increased KCN in restriction. Also, found led resting ventilation adult rats, even after recovery. The effects a low-protein diet followed recovery on...
The lateral parafacial region (pF L ) generates the expiratory motor activity during hypercapnia. It was demonstrated that this contains excitatory neurons and interneurons (with local projections), with a population of glutamatergic are silent under resting conditions, but become active at end expiration, simultaneously in response to hypercapnia/acidosis. However, role pF regulating pulmonary ventilation hypercapnia is unclear. Herein, we hypothesized inhibition attenuates ventilatory...
Ectonucleotidases consist of families nucleotide metabolizing enzymes that hydrolyze extracellular nucleotides, such as ATP, to nucleosides. At the CNS level, these can affect excitability hypothalamic neurons by controlling availability ATP and adenosine. acting on P2 receptor in PVN neurons, is involved hyperosmolality‐induced sympathoexcitation hypertension rats. Therefore, we hypothesized elevated sympathetic activity salt‐induced hypertensive rats occurs parallel a suppression...