A5049948311- Pancreatic and Hepatic Oncology Research
- Neurobiology and Insect Physiology Research
- Olfactory and Sensory Function Studies
- Renal cell carcinoma treatment
- MicroRNA in disease regulation
- Adsorption and biosorption for pollutant removal
- Biochemical Analysis and Sensing Techniques
- Esophageal Cancer Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- RNA modifications and cancer
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Cancer, Hypoxia, and Metabolism
- Peptidase Inhibition and Analysis
- Gut microbiota and health
- Apelin-related biomedical research
- Lung Cancer Diagnosis and Treatment
- Advanced Chemical Sensor Technologies
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Phosphorus and nutrient management
- Radiomics and Machine Learning in Medical Imaging
- Cancer Immunotherapy and Biomarkers
- Medicinal Plants and Bioactive Compounds
Shihezi University
2025
Wenzhou University
2025
Lanzhou Petrochemical Polytechnic
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2015-2024
China Southern Power Grid (China)
2024
Southeast University
2024
Nanjing Medical University
2017-2023
Tianjin Medical University Cancer Institute and Hospital
2013-2023
Huaian First People’s Hospital
2019-2023
National Clinical Research
2023
Five structurally diverse small ligands, all binding to the major urinary protein (MUP) of male house mouse, show individually puberty-accelerating pheromonal activity in recipient females. A recombinant MUP (identical natural protein) has shown no biological activity. While four these ligands were previously implicated oestrus synchronization (Whitten effect), same chemosignals now appear responsible for both sexual maturation and cycling adult
Dendritic zinc (Zn) electrodeposition presents a significant obstacle to the large-scale development of rechargeable zinc-ion batteries. To mitigate this challenge, various interfacial strategies have been employed. However, these approaches often involve incorporation foreign materials onto Zn anode surface, resulting in increased material costs and processing complexities, not mention compromised interface endurability due structural compositional heterogeneity. Realizing that Cu atoms...
Improvement of survival for non-small cell lung cancer over time Wenjie Xia,1–3,* Xinnian Yu,4,* Qixing Mao,1–3,* Wenying Xia,5 Anpeng Wang,1–3 Gaochao Dong,1,2 Bing Chen,1–3 Weidong Ma,1–3 Lin Xu,1,2 Feng Jiang1,2 1Department Thoracic Surgery, Nanjing Medical University Affiliated Cancer Hospital; 2Jiangsu Key Laboratory Molecular and Translational Research, Institute Jiangsu Province, 3The Fourth Clinical College University, 4Department Chemotherapy, Hospital 5Department Medicine, the...
Background/Aims: Subclinical hypothyroidism (SCH) plays a crucial role in the development and progression of coronary heart disease (CHD). However, any associated changes circulating microRNAs (miRNAs) levels slightly elevated thyroid stimulating hormone (TSH) CHD patients are unknown. miR-146a is well known miRNA with inflammatory autoimmune diseases. Here, we evaluated expression patients, goal re-evaluating effect SCH on CHD. Methods: A total 192 study subjects who underwent angiography...
A sensitive biosensor has been developed to detect myoglobin (MB), which is an important cardiac biomarker and plays a major role in the diagnosis of acute myocardial infarction (AMI).
In addressing the performance degradation issue of district cooling systems, although various evaluation methods exist, they either neglect design objectives or focus on independent equipment, overlooking synergies between devices. Therefore, study establishes a comprehensive assessment framework, encompassing efficiency, environmental impact, economic factors, and technological aspects. The Analytic Hierarchy Process (AHP) Entropy Weight Method are employed to determine weights for each...
Mature female mice, grouped in the absence of a male stimulus, exhibit suppressed estrous cycle (the so-called Lee-Boot effect). We have designed series experiments to elucidate involvement adrenal gland this phenomenon. Our initial results indicate that adrenalectomized mice regular either isolated or conditions. A single, intact mouse caged with five females showed repeated normal cycles. When urine samples from group-caged were applied external nares singly females, cycles inhibited...
Hypoxia-inducible factor-1 alpha (HIF-1α) is over-expressed in many cancers including pancreatic ductal adenocarcinoma (PDAC) and correlated with poor prognosis. We aim to determine the effect of germline genetic variants on regulation homeostasis miRNA-gene regulatory loop HIF1A gene PDAC risk. rs2057482 single nucleotide polymorphism (SNP) was genotyped 410 cases 490 healthy controls. The CC genotype SNP significantly risk (OR = 1.719, 95% CI: 1.293-2.286) shorter overall survival (OS,...
Pancreatic cancer is one of the most malignant diseases and has a poor prognosis. The screening validation biomarkers with predictive value for prognosis treatment efficacy are important. To identify potential prognostic markers pancreatic patients, we conducted study that included 99 patients. Three patients PFS>18 months were enrolled in treat group, three PFS<12 control group. Differentially expressed genes (DEGs) between these two groups analyzed by whole-genome expression microarray. A...
Inflammatory reactions mediated by the NACHT, LRR, and PYD domain‐containing protein 3 (NLRP3) inflammasome contributes to non‐small‐cell lung cancer (NSCLC) progression, particularly in patients with bacterial infections. Salidroside (SAL) has recently been shown suppress lipopolysaccharide‐ (LPS‐) induced NSCLC proliferation migration, but its mechanism of action remains unclear. It that SAL improves metabolic inflammation diabetic rodents through AMP‐activated kinase‐ (AMPK‐) dependent...
Coordinating the spatial distribution of crop roots with soil nutrients, along selecting appropriate types fertilizers, is an effective strategy to enhance root nutrient absorption and increase yield. In Xinjiang’s current surface drip irrigation practices for rice (Oryza sativa L.), premature leaf senescence N deficiency are common issues, resulting in decreased yields. This study investigated whether different forms under subsurface can modulate morphological strategies delay later growth...
Aim: Primary clear cell carcinoma of the liver (PCCCL) is a subgroup primary hepatocellular (HCC), pathologically characterized by diffuse cells tumor, showing cytoplasm that does not stain with hematoxylin–eosin. At present, its clinicopathological and prognostic features are fully clarified. This study aims to clarify PCCCL. Methods: The data 43 patients PCCCL treated hepatectomy in our hospital from January 1999 December 2003 were retrospectively analyzed. Results: χ 2 ‐test showed...
Geraniin, a typical ellagitannin isolated from Phyllanthus urinaria Linn, has been found to possess range of bioactive properties. In the present study, we that Geraniin showed potent anti-proliferative effects on human breast cancer MCF-7 cells. The IC50 values were 9.94, 17.98 and 42.32 µM after 72-, 48- 24-h treatment, respectively. Meanwhile, could remarkably disrupt mitochondrial membrane potential arrest S phase cell cycle. Western-blot analysis induced phosphorylation anti-apoptotic...
Background We examined the association between numbers of lymph nodes (LNEs) and accurate staging survival to determine optimal LNE count during esophagectomy using data from Surveillance, Epidemiology, End Results (SEER) cancer registry Department Thoracic Surgery a single institution (SI). Methods A total 7356 EC patients met our inclusion criteria SEER database 1275 SI. applied multivariate models investigate relationship LN metastasis cancer‐specific (CSS). Odds ratios (ORs) hazard (HRs)...
Angoroside C is a phenylpropanoid glycoside compound isolated from the dried root of Scrophularia ningpoensis Hemsl., which possesses effects preventing ventricular remodeling, reducing pulmonary oedema, and blood pressure, as well having properties anti-platelet aggregation, hepatoprotection anti-nephritis, etc. However, few investigations have been conducted on absorption, distribution, metabolism, excretion (ADME) study angoroside C. Thus, fast ultra-high performance liquid...
Objective This study aimed to investigate whether the NLRP3 inflammasome in Kupffer cells (KCs) can be activated response high glucose (HG) and evaluate its influence on hepatic insulin sensitivity. Methods Primary KCs hepatocytes were isolated from mice, lipid accumulation, output, sensitivity of investigated after culturing either alone or with exposed HG. The HG‐induced activation was examined. Treatment gadolinium trichloride caused KC depletion, and, subsequently, a...
<b>Background and Purpose:</b> Few data exist regarding to the occurrence of microembolic high-intensity transient signals (HITS) on transcranial Doppler ultrasound (TCD) in unselected acute stroke patients. The aim this study was investigate prospectively frequency determinants HITS carotid territory ischemia. We hypothesized that artery disease, cardiac abnormalities, nonlacunar infarcts were independent predictors stroke. <b>Methods:</b> investigated 145...